Malate dehydrogenase: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=MDH | |abbr=MDH | ||
|description=''' | |description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD+ to NADH+H+ in the [[TCA cycle]]. Malate is thus a CI-linked substrate. | ||
|info=[http://www.oroboros.at/?Gnaiger_2012_MitoPathways Gnaiger 2012 MitoPathways] | |info=[http://www.oroboros.at/?Gnaiger_2012_MitoPathways Gnaiger 2012 MitoPathways] | ||
|type=Enzyme | |type=Enzyme | ||
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{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Enzyme | |mitopedia topic=Enzyme | ||
|type=Enzyme | |type=Enzyme | ||
}} | }} |
Revision as of 14:55, 19 July 2014
Description
Mitochondrial malate dehydrogenase is localized in the mitochondrial matrix and oxidizes malate, generated from fumarate by fumarase, to oxaloacetate, reducing NAD+ to NADH+H+ in the TCA cycle. Malate is thus a CI-linked substrate.
Abbreviation: MDH
Reference: Gnaiger 2012 MitoPathways
MitoPedia topics: Enzyme