MiP2015

MiP2015

11^th MiPconference on Mitochondrial Physiology

Luční Bouda, Pec pod Snezkou, Czech Republic. 2015 Sep 07-11

Local organizers: Petr Pecina, Tomas Mracek, Josef Houstek (Inst Physiol, Czech Academy of Sciences, Prague, CZ), The MiPsociety.

Email: [email protected]

» MiP2015 Book of Abstracts Open Access

» MiP2015 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ..*

Location: Luční Bouda (Meadows Chalet; 1410 m - http://www.lucnibouda.cz/en ) is located in the Giant Mountains National Park. Luční Bouda is reached from Prague in 2.5 hours. Participants arriving in Prague on Sunday Sep 6 will enjoy a social programme with a visit of the city centre and a boat trip. Transfer by bus from Prague to the conference venue will be arranged with several departures throughout Monday, adjusted to participants’ travel arrangements with arrival before the conference opening in the evening, to enjoy a taste of PAROHÁČ (The STAG) – the locally brewed beer. Bus return transfer to Prague, early morning departure from Luční Bouda.

Programme

Scientific programme

» New: File:MiP2015 Program.pdf

The conference will focus on:

A. Alterations of mitochondrial physiology in pathologic states – mitochondrial diseases, cancer, diabetes etc.

B. Structural basis of mitochondrial physiology – mitochondrial biogenesis, dynamics of mitochondrial supercomplexes, changes of mitochondrial ultrastructure

C. MitoGlobal EAGLE

D. Mitochondrial physiology in life and death of the cell – regulation of mitochondrial energy provision signalling, permeability transition

E. Mitochondria in whole body physiology – exercise physiology, enviromental effects etc.

MiPsociety general assemply

The MiPs general assembly takes place within the MiP2015. MiPconference 2015, Luční Bouda, Pec pod Snezkou, Czech Republic

Date: Thursday, Sept 10

Time: 18:05 - 19:00

Agenda:

1. Report of the Chair

2. Report of the Treasurer

3. Approval of the actions of the Executive MiPcommittee

4. Election of the Executive MiPcommittee

5. MiPmemberships – confirmation of membership fees

6. A new name for the MiPsociety?

7. Upcoming MiPevents

a. MiP2017conference Brazil

b. MiPschool 2017 Egypt

8. Miscellaneous

Social programme

An optional pre-conference social event will be organized in Prague on Sunday 6th evening, including a river boat cruise with dinner and overnight lodging on a boat hotel (80 EUR total).

Registration

Last-minute registrations are encouraged - a special opportunity for students and young investigators:

» Registration & accomodation - until fully booked.

» Abstract submission - closed.

Travel information and additional information

Bus transfer from Prague to the conference venue will be arranged according to participants arrivals in Prague on Monday, September 7th. The conference will start in the evening, and ends on Thursday evening, September 10th. The participants are expected to departure the venue on Friday 11th morning in order to manage departures from Prague in the afternoon. The conference venue is in a National park and cannot be accessed by private vehicles. Private vehicles must be parked in the valley village of Pec pod Snezkou. Transfer up to the venue will be provided by hotel vehicles.

» More info on arrival and departures

» Additional helpful information for your visit in Czech Republic

Impressions of MiP2015

MiP2015: Abstracts

Alphabetical order

	Presentation	Session
Ali 2015 Abstract MiP2015	Mitochondrial function and ROS homeostasis in young mouse heart and brain: the sex factor!	C1 Oral
Amoedo 2015 Abstract MiP2015	The energy requirement of metastatic cells.	A2 Oral
Aoun 2015 Abstract MiP2015	Cellular and animal models for the study of mitochondrial dysfunctions in Neurodegeneration with brain iron accumulation.	A1 Poster
Arava 2015 Abstract MiP2015	Localized translation near mitochondria: novel factors revive old model.	B1 Oral
Barriocanal-Casado 2015 Abstract MiP2015	Targeting nutrient signaling pathways for the treatment of mitochondrial diseases.	A3 Oral
Binko 2015 Abstract MiP2015	Yeast as a system for modeling mitochondrial disease mechanisms and therapies.	A1 Poster
Blecha 2015 Abstract MiP2015	Modulation of mitochondrial electron transport chain activity differentially regulates cell death in proliferating and quiescent cells.	A2 Poster
Boyle 2015 Abstract MiP2015	Kv1.3 channels in mitochondria: Are they important in cellular proliferation?	D1 Oral
Cagin 2015 Abstract MiP2015	Nuclear adaptation to mitochondrial dysfunction.	A1 Oral
Calzia 2015 Abstract MiP2015	Mitochondrial respiration in homogenized small tissue biopsies from the M. Vastus lateralis of patients with Huntington's Disease before and after cycling exercise.	E1 Oral
Cohen 2015 Abstract MiP2015	Ancient out of Africa mitochondrial DNA variants associate with distinct mitochondrial gene expression patterns.	C1 Oral
Devaux 2015 Abstract MiP2015	Mitochondrial complexes I and II behave differently in two anoxia-tolerant species: adaptive mitochondrial plasticity may be related to the ability to undergo metabolic depression.	D1 Poster P-flash
Doerrier 2015 Abstract MiP2015	Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.	D1 Oral
Enriquez 2015 Abstract MiP2015	Superassembly of respiratory complexes: physiological consequences.	B1 Oral
Flannery 2015 Abstract MiP2015	Quantitative live-cell imaging of mitochondrial network morphology in neurodegenerative conditions.	A1 Poster P-flash
Foriel 2015 Abstract MiP2015	Drosophila as a model to study therapeutic approaches for mitochondrial diseases.	A3 Poster P-flash
Galina 2015 Abstract MiP2015	High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles.	C1 Oral
Gnaiger 2015 Abstract MiP2015	Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.	C1 Oral
Hand 2015 Abstract MiP2015	Liposomes simulating the compositions of outer and inner mitochondrial membranes are protected during desiccation by LEA Proteins from Artemia franciscana.	B1 Oral
Hidalgo-Gutierrez 2015 Abstract MiP2015	Strategies to enhance the endogenous biosynthesis of Coenzyme Q.	A3 Oral
Holzerova 2015 Abstract MiP2015	Impairment of reactive oxygen species defense system affects oxidative phosphorylation and causes early-onset neurodegeneration.	A1 Oral
Hoppel 2015 Abstract MiP2015	Effects of ultramarathon performance on mitochondrial respiration in human platelets.	E1 Poster
Huettemann 2015 Abstract MiP2015	Regulation of mitochondrial respiration and apoptosis by cytochrome c phosphorylation.	C1 Poster
Iannetti 2015 Abstract MiP2015	High-Content Screening of mitochondrial morphofunction in living cells.	B1 Oral
Jacobs 2015 Abstract MiP2015	Alternative respiratory chain enzymes in research and therapy.	A3 Oral
Kaambre 2015 Abstract MiP2015	Quantitative characterization of respiratory parameters of human colorectal and breast cancer clinical material.	A2 Poster P-flash
Kalinovich 2015 Abstract MiP2015	UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice.	E1
Kaplanova 2015 Abstract MiP2015	Functional ablation of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice.	A1 Poster P-flash
Karabatsiakis 2015 Abstract MiP2015	Mitochondrial respiration of peripheral blood mononuclear cells in patients with borderline personality disorder.	C1 Oral
Karbanova 2015 Abstract MiP2015	CD36 does not directly participate in mitochondrial fatty acid transport and oxidation.	E1 Poster
Komelina 2015 Abstract MiP2015	Artificial hypothermia of rats, as opposed to natural hibernation of ground squirrels Spermophilus undulatus, is not accompanied by inhibition of mitochondrial respiration in liver.	E1 Poster
Koopman 2015 Abstract MiP2015	Mitoenergetic dysfunction triggers a rapid compensatory increase in steady-state glucose flux.	D1 Oral
Kovalcikova 2015 Abstract MiP2015	Derangements of myocardial mitochondrial function in patients with end-stage heart failure is associated with reduced endonuclease G.	A1 Oral
Kovarova 2015 Abstract MiP2015	Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.	B1 Poster
Kratochvilova 2015 Abstract MiP2015	Mitochondrial dysfunction in Niemann Pick type C1 patient´s cells and tissues.	A1 Poster
Laner 2015 Abstract MiP2015	Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.	E1 Oral
Lettlova 2015 Abstract MiP2015	Role of the microRNA-301a in the regulation of mitochondrial function in cancer cells.	A2 Poster
Lippe 2015 Abstract MiP2015	The channel function of the F-ATP synthase complex and its role in the mitochondrial permeability transition.	D1 Oral
Lopez 2015 Abstract MiP2015	Unraveling the causes of the clinical heterogeneity of coenzyme Q10 deficiency due to different molecular defects in Coq9 gene.	A1 Oral
Lytovchenko 2015 Abstract MiP2015	Mitochondrial metabolite transport in cancer cells.	A2 Poster
Matakovic 2015 Abstract MiP2015	Cofactor deficiency in mitochondrial diseases.	A1 Oral Poster P-flash
McManus 2015 Abstract MiP2015	The etiology of age-dependent disease: a story of two genomes.	A1 Oral
Mishmar 2015 Abstract MiP2015	Mitochondrial 16S rRNA is methylated (m1A) throughout vertebrate evolution to maintain protein synthesis and cell growth.	C1 Oral
Mracek 2015 Abstract MiP2015	Myocardial iron and mitochondrial function in failing and non-failing human heart: direct tissue analysis.	A1 Poster
Nuskova 2015 Abstract MiP2015	Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies?	B1 Oral
Pecina 2015 Abstract MiP2015	Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells.	A2
Pecinova 2015 Abstract MiP2015	Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue.	E1 Oral Poster
Renshaw 2015 Abstract MiP2015	Mitochondrial responses to thermal stress: is the ability to withstand anoxia-induced stress associated with cross-tolerance to thermal stress?	D1
Rieger 2015 Abstract MiP2015	pH nanoenvironment sensing in actively respiring mitochondria.	B1 Oral
Rodinova 2015 Abstract MiP2015	Altered mitochondrial ultrastructure, reduced respiration and decreased level of PDH subunits in fibroblasts from 10 patients with Huntington’s disease.	A1 Oral
Rohlena 2015 Abstract MiP2015	Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation.	A2 Poster
Rohlenova 2015 Abstract MiP2015	Mitochondrial targeting of tamoxifen enhances its activity against Her2^high breast cancer.	A2 Oral
Salin 2015 Abstract MiP2015	Individual variation in whole-organism performance is related to mitochondrial properties at high temperatures.	E1
Sanchez 2015 Abstract MiP2015	Novel complex I assembly factor mutation leads to adult phenotype.	A1 Poster
Shabalina 2015 Abstract MiP2015	The metabolically inert environmental pollutants perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.	E1
Shevchuk 2015 Abstract MiP2015	Analysis of energy fluxes in colorectal cancer saponin skinned tissues and Caco-2 cells.	A2 Poster
Shoubridge 2015 Abstract MiP2015	Posttranscriptional regulation of mitochondrial gene expression.	A1 Oral
Skulachev 2015 Abstract MiP2015	Moscow news: two more representatives of sodium motive force generators (Na⁺-cbb3 oxidase and Na⁺-bacteriorhodopsin); natural delay of the aging program (neoteny) in mammals, namely in naked mole rat and “naked ape” (human).	D1
Sleiman 2015 Abstract MiP2015	Mitochondrial respiration in sequential biospies from skeletal muscles during hemorrhagic shock and over the course of 48h of reperfusion in pigs.	A1 Poster
Sumbalova 2015 Abstract MiP2015	High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.	D1
Suzuki-Karasaki 2015 Abstract MiP2015	L-type calcium channels prevent mitochondrial network disruption in human cancer cells.	A2 Oral
Takaharu 2015 Abstract MiP2015	Higd1a is a positive regulator of cytochrome c oxidase.	B1 Oral
Taleva 2015 Abstract MiP2015	A new look at the bioenergetics of the bloodstream Trypanosoma brucei mitochondrion.	D1
Tanaka 2015 Abstract MiP2015	GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases.	A3 Oral
Tauchmannova 2015 Abstract MiP2015	Assembly of subunit F_o-a into mammalian ATP synthase.	B1 Oral
Template 2015 Abstract MiP2015
Tepp 2015 Abstract MiP2015	Changes in energy transfer regulation during development and aging.	D1 Poster P-flash
Vatrinet 2015 Abstract MiP2015	Targeting complex I as an anticancer strategy.	A2 Oral
Vidali 2015 Abstract MiP2015	Alterations of the OXPHOS system in rhabdomyosarcomas.	A2 Poster P-flash
Weidgang 2015 Abstract MiP2015	Mitochondrial respiration in homogenized biopsies from kidney, liver, heart and diaphragm from mice after blunt thoracic trauma and hemorrhagic shock. Effects of a novel hydrogen sulfide donor AP39.	A1 Oral

» MiP2015 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ..*

^* Further information - Make full use of the MiPMap

Sessions

» MiP2015 Book of Abstracts Open Access

Session A

Session A1

Tuesday, Sep 08 »Help - Further information - Make full use of the MiPMap

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Aoun 2015 Abstract MiP2015	A1 Poster	Cellular and animal models for the study of mitochondrial dysfunctions in Neurodegeneration with brain iron accumulation.	Respiration mtDNA;mt-genetics nDNA;cell genetics Exercise physiology;nutrition;life style Patients	Human Mouse	Nervous system Blood cells Fibroblast		Neurodegenerative
Binko 2015 Abstract MiP2015	A1 Poster	Yeast as a system for modeling mitochondrial disease mechanisms and therapies.	mt-Membrane mtDNA;mt-genetics Patients	Saccharomyces cerevisiae		Mitochondrial disease
Cagin 2015 Abstract MiP2015	A1 Oral	Nuclear adaptation to mitochondrial dysfunction.	mt-Membrane mtDNA;mt-genetics nDNA;cell genetics
Flannery 2015 Abstract MiP2015	A1 Poster P-flash	Quantitative live-cell imaging of mitochondrial network morphology in neurodegenerative conditions.	Instruments;methods mt-Structure;fission;fusion mt-Membrane mtDNA;mt-genetics mt-Medicine		Fibroblast	Mitochondrial disease	Other
Holzerova 2015 Abstract MiP2015	A1 Oral	Impairment of reactive oxygen species defense system affects oxidative phosphorylation and causes early-onset neurodegeneration.	nDNA;cell genetics mt-Medicine Patients			Oxidative stress;RONS	Neurodegenerative
Kratochvilova 2015 Abstract MiP2015	A1 Poster	Mitochondrial dysfunction in Niemann Pick type C1 patient´s cells and tissues.	Respiration nDNA;cell genetics Patients	Human	Nervous system Liver Fibroblast	Mitochondrial disease	Neurodegenerative
Lopez 2015 Abstract MiP2015	A1 Oral	Unraveling the causes of the clinical heterogeneity of coenzyme Q10 deficiency due to different molecular defects in Coq9 gene.	Respiration nDNA;cell genetics	Mouse	Skeletal muscle	Mitochondrial disease	Other
Matakovic 2015 Abstract MiP2015	A1 Oral Poster P-flash	Cofactor deficiency in mitochondrial diseases.	Respiration mtDNA;mt-genetics mt-Medicine Patients	Human		Mitochondrial disease
McManus 2015 Abstract MiP2015	A1 Oral	The etiology of age-dependent disease: a story of two genomes.	mtDNA;mt-genetics nDNA;cell genetics	Human			Aging;senescence Cardiovascular
Rodinova 2015 Abstract MiP2015	A1 Oral	Altered mitochondrial ultrastructure, reduced respiration and decreased level of PDH subunits in fibroblasts from 10 patients with Huntington’s disease.	Respiration mtDNA;mt-genetics Patients	Human Pig	Endothelial;epithelial;mesothelial cell Fibroblast	Mitochondrial disease	Neurodegenerative
Sanchez 2015 Abstract MiP2015	A1 Poster	Novel complex I assembly factor mutation leads to adult phenotype.	mtDNA;mt-genetics Patients	Human
Sleiman 2015 Abstract MiP2015	A1 Poster	Mitochondrial respiration in sequential biospies from skeletal muscles during hemorrhagic shock and over the course of 48h of reperfusion in pigs.	Respiration	Pig	Skeletal muscle	Ischemia-reperfusion
Weidgang 2015 Abstract MiP2015	A1 Oral	Mitochondrial respiration in homogenized biopsies from kidney, liver, heart and diaphragm from mice after blunt thoracic trauma and hemorrhagic shock. Effects of a novel hydrogen sulfide donor AP39.	Respiration Comparative MiP;environmental MiP	Mouse	Heart Skeletal muscle Liver Kidney	Ischemia-reperfusion
Shoubridge 2015 Abstract MiP2015	A1 Oral	Posttranscriptional regulation of mitochondrial gene expression.	mt-Biogenesis;mt-density mtDNA;mt-genetics			Mitochondrial disease
Kaplanova 2015 Abstract MiP2015	A1 Poster P-flash	Functional ablation of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice.	Respiration mt-Biogenesis;mt-density mt-Membrane Genetic knockout;overexpression	Mouse	Heart
Mracek 2015 Abstract MiP2015	A1 Poster	Myocardial iron and mitochondrial function in failing and non-failing human heart: direct tissue analysis.	Respiration mt-Medicine Patients	Human	Heart		Cardiovascular Diabetes
Kovalcikova 2015 Abstract MiP2015	A1 Oral	Derangements of myocardial mitochondrial function in patients with end-stage heart failure is associated with reduced endonuclease G.	Respiration Patients	Human	Heart	Ischemia-reperfusion	Cardiovascular

Session A2

Tuesday, Sep 08 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Amoedo 2015 Abstract MiP2015	A2 Oral	The energy requirement of metastatic cells.	Respiration mt-Biogenesis;mt-density mt-Membrane	Mouse Rat	Other cell lines		Cancer
Lettlova 2015 Abstract MiP2015	A2 Poster	Role of the microRNA-301a in the regulation of mitochondrial function in cancer cells.	mt-Biogenesis;mt-density mtDNA;mt-genetics Pharmacology;toxicology mt-Awareness			Oxidative stress;RONS	Cancer
Lytovchenko 2015 Abstract MiP2015	A2 Poster	Mitochondrial metabolite transport in cancer cells.	mt-Membrane		Other cell lines	Oxidative stress;RONS	Cancer
Rohlena 2015 Abstract MiP2015	A2 Poster	Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation.	Respiration mt-Membrane	Human	Other cell lines	Cell death Oxidative stress;RONS
Kaambre 2015 Abstract MiP2015	A2 Poster P-flash	Quantitative characterization of respiratory parameters of human colorectal and breast cancer clinical material.	Respiration Instruments;methods mt-Membrane	Human	Endothelial;epithelial;mesothelial cell		Cancer
Shevchuk 2015 Abstract MiP2015	A2 Poster	Analysis of energy fluxes in colorectal cancer saponin skinned tissues and Caco-2 cells.	Respiration Instruments;methods Comparative MiP;environmental MiP mt-Medicine Patients	Human	Endothelial;epithelial;mesothelial cell		Cancer
Vatrinet 2015 Abstract MiP2015	A2 Oral	Targeting complex I as an anticancer strategy.	nDNA;cell genetics Genetic knockout;overexpression mt-Medicine	Human		Oxidative stress;RONS	Cancer
Vidali 2015 Abstract MiP2015	A2 Poster P-flash	Alterations of the OXPHOS system in rhabdomyosarcomas.	Respiration Genetic knockout;overexpression Comparative MiP;environmental MiP Patients	Human Mouse	Skeletal muscle		Cancer
Rohlenova 2015 Abstract MiP2015	A2 Oral	Mitochondrial targeting of tamoxifen enhances its activity against Her2^high breast cancer.	mt-Medicine Pharmacology;toxicology			Oxidative stress;RONS	Cancer
Suzuki-Karasaki 2015 Abstract MiP2015	A2 Oral	L-type calcium channels prevent mitochondrial network disruption in human cancer cells.	Comparative MiP;environmental MiP mt-Medicine	Human		Cell death	Cancer
Pecina 2015 Abstract MiP2015	A2	Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells.	Respiration Instruments;methods nDNA;cell genetics Pharmacology;toxicology	Human		Cell death	Cancer
Blecha 2015 Abstract MiP2015	A2 Poster	Modulation of mitochondrial electron transport chain activity differentially regulates cell death in proliferating and quiescent cells.	Respiration			Cell death Oxidative stress;RONS

Session A3

Tuesday, Sep 08 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Barriocanal-Casado 2015 Abstract MiP2015	A3 Oral	Targeting nutrient signaling pathways for the treatment of mitochondrial diseases.	Respiration mtDNA;mt-genetics Pharmacology;toxicology	Mouse		Mitochondrial disease
Foriel 2015 Abstract MiP2015	A3 Poster P-flash	Drosophila as a model to study therapeutic approaches for mitochondrial diseases.	Instruments;methods mtDNA;mt-genetics mt-Medicine Pharmacology;toxicology			Mitochondrial disease
Hidalgo-Gutierrez 2015 Abstract MiP2015	A3 Oral	Strategies to enhance the endogenous biosynthesis of Coenzyme Q.	mtDNA;mt-genetics mt-Medicine Pharmacology;toxicology	Mouse	Skeletal muscle Nervous system Kidney Fibroblast	Mitochondrial disease	Other
Tanaka 2015 Abstract MiP2015	A3 Oral	GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases.	Respiration mtDNA;mt-genetics nDNA;cell genetics Patients		Other cell lines	Mitochondrial disease
Jacobs 2015 Abstract MiP2015	A3 Oral	Alternative respiratory chain enzymes in research and therapy.	nDNA;cell genetics mt-Medicine mt-Awareness	Human Mouse Drosophila Other invertebrates		Mitochondrial disease	Alzheimer's Neurodegenerative Parkinson's

Session B

Wednesday, Sep 09 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Arava 2015 Abstract MiP2015	B1 Oral	Localized translation near mitochondria: novel factors revive old model.	mt-Membrane mtDNA;mt-genetics nDNA;cell genetics
Hand 2015 Abstract MiP2015	B1 Oral	Liposomes simulating the compositions of outer and inner mitochondrial membranes are protected during desiccation by LEA Proteins from Artemia franciscana.	mt-Membrane
Takaharu 2015 Abstract MiP2015	B1 Oral	Higd1a is a positive regulator of cytochrome c oxidase.	mtDNA;mt-genetics	Rat	Heart	Oxidative stress;RONS
Rieger 2015 Abstract MiP2015	B1 Oral	pH nanoenvironment sensing in actively respiring mitochondria.	mt-Structure;fission;fusion mt-Membrane	Human	HeLa
Iannetti 2015 Abstract MiP2015	B1 Oral	High-Content Screening of mitochondrial morphofunction in living cells.	Instruments;methods mt-Medicine Pharmacology;toxicology			Mitochondrial disease
Enriquez 2015 Abstract MiP2015	B1 Oral	Superassembly of respiratory complexes: physiological consequences.
Tauchmannova 2015 Abstract MiP2015	B1 Oral	Assembly of subunit F_o-a into mammalian ATP synthase.	mt-Biogenesis;mt-density mt-Membrane mtDNA;mt-genetics Genetic knockout;overexpression	Human	Other cell lines HEK
Nuskova 2015 Abstract MiP2015	B1 Oral	Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies?	Genetic knockout;overexpression	Human	HEK	Oxidative stress;RONS
Kovarova 2015 Abstract MiP2015	B1 Poster	Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.	mtDNA;mt-genetics Comparative MiP;environmental MiP Patients	Human Mouse	Fibroblast		Neurodegenerative

Session C

Thursday, Sep 10 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Cohen 2015 Abstract MiP2015	C1 Oral	Ancient out of Africa mitochondrial DNA variants associate with distinct mitochondrial gene expression patterns.	mtDNA;mt-genetics nDNA;cell genetics Comparative MiP;environmental MiP	Human
Gnaiger 2015 Abstract MiP2015	C1 Oral	Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.	Respiration Instruments;methods mt-Membrane	Human	HEK	Cryopreservation Oxidative stress;RONS
Karabatsiakis 2015 Abstract MiP2015	C1 Oral	Mitochondrial respiration of peripheral blood mononuclear cells in patients with borderline personality disorder.	Respiration Patients	Human	Blood cells	Cryopreservation	Other
Ali 2015 Abstract MiP2015	C1 Oral	Mitochondrial function and ROS homeostasis in young mouse heart and brain: the sex factor!	Respiration Gender	Mouse	Heart Nervous system
Mishmar 2015 Abstract MiP2015	C1 Oral	Mitochondrial 16S rRNA is methylated (m1A) throughout vertebrate evolution to maintain protein synthesis and cell growth.	Instruments;methods mtDNA;mt-genetics Comparative MiP;environmental MiP	Human Eubacteria
Huettemann 2015 Abstract MiP2015	C1 Poster	Regulation of mitochondrial respiration and apoptosis by cytochrome c phosphorylation.			Kidney	Cell death	Obesity
Galina 2015 Abstract MiP2015	C1 Oral	High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles.	Respiration Exercise physiology;nutrition;life style	Rat	Skeletal muscle

Session D

Thursday, Sep 10 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Boyle 2015 Abstract MiP2015	D1 Oral	Kv1.3 channels in mitochondria: Are they important in cellular proliferation?	Respiration mt-Membrane	Human	Endothelial;epithelial;mesothelial cell HEK
Devaux 2015 Abstract MiP2015	D1 Poster P-flash	Mitochondrial complexes I and II behave differently in two anoxia-tolerant species: adaptive mitochondrial plasticity may be related to the ability to undergo metabolic depression.	Respiration Comparative MiP;environmental MiP	Fishes	Nervous system	Ischemia-reperfusion Oxidative stress;RONS
Doerrier 2015 Abstract MiP2015	D1 Oral	Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.	Respiration Instruments;methods Exercise physiology;nutrition;life style	Mouse	Heart	Oxidative stress;RONS
Koopman 2015 Abstract MiP2015	D1 Oral	Mitoenergetic dysfunction triggers a rapid compensatory increase in steady-state glucose flux.			Skeletal muscle Other cell lines
Renshaw 2015 Abstract MiP2015	D1	Mitochondrial responses to thermal stress: is the ability to withstand anoxia-induced stress associated with cross-tolerance to thermal stress?	Respiration Comparative MiP;environmental MiP	Fishes	Nervous system	Oxidative stress;RONS Temperature
Skulachev 2015 Abstract MiP2015	D1	Moscow news: two more representatives of sodium motive force generators (Na⁺-cbb3 oxidase and Na⁺-bacteriorhodopsin); natural delay of the aging program (neoteny) in mammals, namely in naked mole rat and “naked ape” (human).	Respiration nDNA;cell genetics Comparative MiP;environmental MiP	Human Other mammals Eubacteria	Heart Nervous system	Cell death Oxidative stress;RONS	Aging;senescence
Sumbalova 2015 Abstract MiP2015	D1	High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.	Respiration Instruments;methods mt-Membrane	Mouse	Nervous system
Taleva 2015 Abstract MiP2015	D1	A new look at the bioenergetics of the bloodstream Trypanosoma brucei mitochondrion.	mt-Biogenesis;mt-density mtDNA;mt-genetics Comparative MiP;environmental MiP	Protists
Tepp 2015 Abstract MiP2015	D1 Poster P-flash	Changes in energy transfer regulation during development and aging.	Respiration		Heart		Aging;senescence
Lippe 2015 Abstract MiP2015	D1 Oral	The channel function of the F-ATP synthase complex and its role in the mitochondrial permeability transition.	Respiration mt-Membrane mtDNA;mt-genetics

Session E

Thursday, Sep 10 »Help

	Session	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states
Calzia 2015 Abstract MiP2015	E1 Oral	Mitochondrial respiration in homogenized small tissue biopsies from the M. Vastus lateralis of patients with Huntington's Disease before and after cycling exercise.	Respiration Exercise physiology;nutrition;life style Patients	Human	Skeletal muscle		Other
Hoppel 2015 Abstract MiP2015	E1 Poster	Effects of ultramarathon performance on mitochondrial respiration in human platelets.	Respiration Exercise physiology;nutrition;life style	Human	Blood cells Platelet	Oxidative stress;RONS
Laner 2015 Abstract MiP2015	E1 Oral	Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.	Respiration Instruments;methods Comparative MiP;environmental MiP	Dog	Skeletal muscle
Kalinovich 2015 Abstract MiP2015	E1	UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice.	Respiration mt-Membrane nDNA;cell genetics Genetic knockout;overexpression Comparative MiP;environmental MiP	Mouse	Fat
Komelina 2015 Abstract MiP2015	E1 Poster	Artificial hypothermia of rats, as opposed to natural hibernation of ground squirrels Spermophilus undulatus, is not accompanied by inhibition of mitochondrial respiration in liver.	Respiration Comparative MiP;environmental MiP	Rat Other mammals	Liver	Oxidative stress;RONS Temperature
Salin 2015 Abstract MiP2015	E1	Individual variation in whole-organism performance is related to mitochondrial properties at high temperatures.	Respiration Comparative MiP;environmental MiP Exercise physiology;nutrition;life style	Fishes	Skeletal muscle Liver	Temperature
Shabalina 2015 Abstract MiP2015	E1	The metabolically inert environmental pollutants perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.	mt-Membrane Comparative MiP;environmental MiP Pharmacology;toxicology	Mouse	Fat
Karbanova 2015 Abstract MiP2015	E1 Poster	CD36 does not directly participate in mitochondrial fatty acid transport and oxidation.	mt-Membrane nDNA;cell genetics Comparative MiP;environmental MiP	Rat	Fat
Pecinova 2015 Abstract MiP2015	E1 Oral Poster	Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue.	Comparative MiP;environmental MiP	Rat	Fat		Diabetes Obesity

» MitoPedia: Respiratory states     -

Invited speakers

* Eric A. Shoubridge - McGill University, Montreal, Canada (cancelled)

Meagan McManus - Children's Hospital of Philadelphia, USA
Ali S. Sameh - Helmy Institute of Medical Sciences, Giza, Egypt
Jose A. Enriquez - Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
Antonio Galina, Universidade Federal do Rio de Janeiro, Brazil
Giovanna Lippe – University of Udine, Italy
Howard Jacobs – University of Tampere, Finland
Maik Hüttemann – Wayne State University, Detroit, USA