Outlier-skewness index |

**MitoPedia O2k and high-resolution respirometry:**
O2k-Open Support

## Description

An **outlier-skewness index** *OSI* is defined for evaluation of the distribution of data sets with outliers including separate clusters or skewness in relation to a normal distribution with equivalence of the average and median. The *OSI* is derived from Pearsonβs coefficient of skewness 2:

- Pearson 2 coefficient = 3 Β· (average-median)/SD

The outlier-skewness index *OSI* introduces the absolute value of the arithmetic mean, *m* = ABS(average + median)/2, for normalization:

*OSI*= (average-median)/(*m*+ SD)

*OSI*= (average-median)/[ABS(average+median)/2 + SD]

At the limit of a zero value of *m*, the *OSI* equals the Pearson 2 coefficient (without the multiplication factor of 3). At high *m* with small standard deviation (SD), the *OSI* is effectively the difference between the average and the median normalized for *m*, (average-median)/*m*.

**Abbreviation:** *OSI*, *OI*

Communicated by Gnaiger E (2016-10-03) updated 2021-06-26

- Β» Doane DP, Seward LE (2011) Measuring skewness: a forgotten statistic?. J Statistics Education 19,2:1-18. β Β»Bioblast linkΒ«
- Β» Pearsonβs coefficient of skewness

## The outlier index in DatLab

- In Marks - DatLab opened by clicking on the bar of a mark in the DatLab window, the outlier index
*OI*(equivalent to*OSI*) is shown for the data set selected by the mark on a specific plot. It is more specific than Pearsonβs coefficient of skewness for targeting outliers or separate clusters in data series recorded with the O2k. The threshold of the absolute value of the*OSI*(*OI*) is set at 0.05. If ABS(*OSI*)>0.05 calculated for the data points within a defined Mark, the Mark window indicates the likely occurrence of outliers in the data sequence. In the Mark window the 'Outlier index threshold' can be set to a lab-specific or session-specific value (Lab-default or Session value) different from the System default.

- In Marks - DatLab opened by clicking on the bar of a mark in the DatLab window, the outlier index

**MitoPedia O2k and high-resolution respirometry:**
DatLab,
Oroboros QM