From Bioblast

high-resolution terminology - matching measurements at high-resolution



Peripheral blood mononuclear cells (PBMC) are a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets (PLT) can be found in the PBMC fraction, where PLT are considered as a contamination.

Abbreviation: PBMC

Reference: MiPNet21.17 BloodCellsIsolation

Cell size

  • Lymphocytes: 210 fL volume; 7 to 10 Β΅m diameter [1]
  • Monocytes: 180 fL volume; 15 to 25 Β΅m diameter [2]


  1. Segel GB, Cokelet GR, Lichtman MA (1981) The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood 57:894-9
  2. Mardi D, Fwity B, Lobmann R, Ambrosch A (2010) Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8
Β» O2k-Publications: PBMC
Cookies help us deliver our services. By using our services, you agree to our use of cookies.