ZA Cape Town Mendham A
| O2k-Network Lab | Division of Physiological Sciences, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, ZA |
|---|---|
| Address | Boundary Rd, Newlands, 7945 |
| City | Cape Town |
| State/Prov | |
| Country | South Africa |
| Weblink | |
| Contact | Mendham Amy |
| Team | Andrew Brittany, Feldmann Daneil, George Siddiqah, Leith David, Madlala Hlengiwe, Osiki Prisca, Webster Christopher, Kariem Neezaam. |
| Team previous | Smith James, Bezuidenhout Nicole, Maarman Gerald |
| Status | 3 Power-O2k 2017-; previous: ZA Cape Town Ojuka EO |
| Oroboros Events | MitoEAGLE 2018 LV, MiPschool 2017, IOC122, MitoFit Science Camp 2016, IOC106, MiPschool 2015, IOC99, IOC96, MiP2014, IOC95 |
| Topics |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Madlala 2019 Integr Food Nutr Metab | 2019 | Madlala HP, Maarman GJ, Ojuka E (2019) Fructose impairs mitochondrial respiration and substrate utilization in hepatocytes via the enzyme, glutamate oxaloacetate transaminase. Integr Food Nutr Metab doi: 10.15761/IFNM.1000228. |
| Kriel 2018 Sci Rep | 2018 | Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348. |
| Victor 2017 Thesis | 2017 | Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76. |
| Osiki 2016 FASEB J | 2016 | Osiki PO, Ojuka E, Marmaan G (2016) An investigation of the suitability of using octanoylcarnitine together with malate as a substrate combination for assessing Beta-oxidation using High Resolution Respirometry. FASEB J 30: 1015.12 . |
| Ojuka 2016 Am J Physiol Endocrinol Metab | 2016 | Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of Ξ²-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015 |
O2k-Abstracts
| Published | Reference | |
|---|---|---|
| Bezuidenhout 2016a Abstract MitoFit Science Camp 2016 | 2016 | Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin. |
| Bezuidenhout 2016b Abstract MitoFit Science Camp 2016 | 2016 | Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers. |
| Osiki 2016 Abstract MitoFit Science Camp 2016 | 2016 | Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples. |
| Madlala 2016 Abstract MitoFit Science Camp 2016 | 2016 | Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates. |
| Maarman 2016 Abstract MitoFit Science Camp 2016 | 2016 | Melatonin rescues uric acid-induced impairment of respiration in myotubes. |
| Madlala 2015 Abstract MiPschool Cape Town 2015 | 2015 | Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-Ξ²1. |
| Ojuka 2015 Abstract MiPschool Cape Town 2015 | 2015 | Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation. |
| Bezuidenhout 2015 Abstract MiPschool Cape Town 2015 | 2015 | A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle. |
| George 2015 Abstract MiPschool Cape Town 2015 | 2015 | Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats. |
| Maarman 2015 Abstract MiPschool Cape Town 2015 | 2015 | Characterisation of mitochondrial function in a model of pulmonary hypertension-induced right ventricular failure. |
