Bioblast: Difference between revisions
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[[Image:MitoPedia.jpg|left|100px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]] Β | [[Image:MitoPedia.jpg|left|100px|link=http://www.bioblast.at/index.php/MitoPedia|MitoPedia]] Β | ||
<big>Dear colleagues: | Β | ||
<br /> | <big><big>Dear colleagues: | ||
<br /><br /> | |||
Over the past years, there was a continuous struggle to find a language for translating our experimental findings obtained from [[SUIT protocols]] into useful information. Β | Over the past years, there was a continuous struggle to find a language for translating our experimental findings obtained from [[SUIT protocols]] into useful information. Β | ||
<br /> | <br /><br /> | ||
Still our standard terminology and some even less consistent variations are not commonly understandable. Despite all efforts, including sequential editions of βMitoPathwaysβ ([[Gnaiger 2014 MitoPathways |The Blue Book]]), those attempts were basically a failure: We cannot expect any audience to grasp our message, if we say βComplex Iβ β | Still our standard terminology and some even less consistent variations are not commonly understandable. Despite all efforts, including sequential editions of βMitoPathwaysβ ([[Gnaiger 2014 MitoPathways |The Blue Book]]), those attempts were basically a failure: We cannot expect any audience to grasp our message, if we say βComplex Iβ β yet actually have in mind the pathway from NADH-linked substrates to CI - CIII - CIV. Should we rather say CI-CIII-CIV-linked ??? | ||
<br /> | <br /><br /> | ||
Or even worse (my mistake!): We say βCI<small>&</small>IIβ (and worse: βCI+IIβ: are the two enzymes added??), but we actually mean CI<small>&</small>II - CIII - CIV !!! | Or even worse (my mistake!): We say βCI<small>&</small>IIβ (and worse: βCI+IIβ: are the two enzymes added??), but we actually mean CI<small>&</small>II - CIII - CIV !!! | ||
<br /> | <br /><br /> | ||
I invite you to challenge fundamentally the way we think and talk and write about our results. To drop the CI-linked, CII-linked, CI<small>&</small>II (CI+II) terminology is not trivial but is a necessary step. At this stage, you and many colleagues will not like to make a real change. But such a change is not only important but necessary to make ourselves understood by a general audience, to make our field of mitochondrial physiology less confusing and more attractive. Perhaps we can even attain a deeper understanding among the involved specialists - the Bioblasts. | I invite you to challenge fundamentally the way we think and talk and write about our results. To drop the CI-linked, CII-linked, CI<small>&</small>II (CI+II) terminology is not trivial but is a necessary step. At this stage, you and many colleagues will not like to make a real change. But such a change is not only important but necessary to make ourselves understood by a general audience, to make our field of mitochondrial physiology less confusing and more attractive. Perhaps we can even attain a deeper understanding among the involved specialists - the Bioblasts. | ||
<br /> | <br /><br /> | ||
If you agree that in mitochondrial respiratory physiology we should '''not say βComplex Iβ for what IS NOT Complex I''', that we should not talk about a subset of '''enzyme complexes''' when we have in mind much more '''complicated pathways''' fuelled by a selection and combination of specific '''substrate types''', then I seriously ask you to stop for a moment and take a look at some new entries into MitoPedia which I have prepared during the past months. | If you agree that in mitochondrial respiratory physiology we should '''not say βComplex Iβ for what IS NOT Complex I''', that we should not talk about a subset of '''enzyme complexes''' when we have in mind much more '''complicated pathways''' fuelled by a selection and combination of specific '''substrate types''', then I seriously ask you to stop for a moment and take a look at some new entries into MitoPedia which I have prepared during the past months. | ||
<br /> | <br /> | ||
Β | :Β» Substrate types and pathway types: [[Substrate types]]<br /> | ||
:Β» Substrate types and pathway types: [[Substrate types]] | :Β» [[Categories of SUIT protocols]]<br /> | ||
<br /> | :Β» [[SUIT protocol names]]<br /> | ||
:Β» [[Categories of SUIT protocols]] | |||
<br /> | |||
:Β» [[SUIT protocol names]] | |||
<br /> | <br /> | ||
I am looking forward to your feedback. Your input will be essential to find a common language for communication with the people whom we want to reach with our research in mitochondrial physiology. Lets cooperate in an effort on quality management of reporting our results. The messages of mitochondrial physiology need to be understood on a global scale, to support the various health systems in encouraging modern populations to become and stay [[MitoFit]]. Β | I am looking forward to your feedback. Your input will be essential to find a common language for communication with the people whom we want to reach with our research in mitochondrial physiology. Lets cooperate in an effort on quality management of reporting our results. The messages of mitochondrial physiology need to be understood on a global scale, to support the various health systems in encouraging modern populations to become and stay [[MitoFit]]. | ||
<br /> | </big><br /> | ||
With best wishes and kind regards, | With best wishes and kind regards, | ||
<br /> | <br /><br /> | ||
[[Gnaiger E |Erich]] | [[Gnaiger E |Erich]] |
Revision as of 22:04, 10 February 2016
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Bioblast alert 2016(01): 2016-02-10
Over the past years, there was a continuous struggle to find a language for translating our experimental findings obtained from SUIT protocols into useful information.
Still our standard terminology and some even less consistent variations are not commonly understandable. Despite all efforts, including sequential editions of βMitoPathwaysβ (The Blue Book), those attempts were basically a failure: We cannot expect any audience to grasp our message, if we say βComplex Iβ β yet actually have in mind the pathway from NADH-linked substrates to CI - CIII - CIV. Should we rather say CI-CIII-CIV-linked ???
Or even worse (my mistake!): We say βCI&IIβ (and worse: βCI+IIβ: are the two enzymes added??), but we actually mean CI&II - CIII - CIV !!!
I invite you to challenge fundamentally the way we think and talk and write about our results. To drop the CI-linked, CII-linked, CI&II (CI+II) terminology is not trivial but is a necessary step. At this stage, you and many colleagues will not like to make a real change. But such a change is not only important but necessary to make ourselves understood by a general audience, to make our field of mitochondrial physiology less confusing and more attractive. Perhaps we can even attain a deeper understanding among the involved specialists - the Bioblasts.
If you agree that in mitochondrial respiratory physiology we should not say βComplex Iβ for what IS NOT Complex I, that we should not talk about a subset of enzyme complexes when we have in mind much more complicated pathways fuelled by a selection and combination of specific substrate types, then I seriously ask you to stop for a moment and take a look at some new entries into MitoPedia which I have prepared during the past months.
I am looking forward to your feedback. Your input will be essential to find a common language for communication with the people whom we want to reach with our research in mitochondrial physiology. Lets cooperate in an effort on quality management of reporting our results. The messages of mitochondrial physiology need to be understood on a global scale, to support the various health systems in encouraging modern populations to become and stay MitoFit.
With best wishes and kind regards,
Erich
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