DTPA: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=DTPA | |abbr=DTPA | ||
|description='''DTPA''' (Diethylentriamin-N,N,N',N,N- | |description='''DTPA''' (Diethylentriamin-N,N,N',N,N-penta acetic acid, "Triplex V") is a chelator of transition metals, not cell membrane permeable. Β | ||
}} | }} | ||
Β | |||
== Description == | |||
Β | |||
::::* CAS: 67-43-6 | |||
::::* Source: EHERE13095000 VWR 0.25 g | |||
::::* M: 393,35 g/mol | |||
::::* Stability constants not included in NIST version of Martell 1989, constants from [http://www.dojindo.com/Images/Product%20Photo/Chelate_Table_of_Stability_Constants.pdf]: Ca2+: 10.74 (EDTA 10.96), Mg2+: 9.3 (EDTA: 8.69) Fe II 16.5 (EDTA 14.3), Fe III 28.6 (EDTA 25.1) Mn II 15.6 (EDTA 14.04), ZN 18.75 (EDTA 16.5), general chelates multivalent ions stronger than EDTA; pKa1 = 2.14, pKa2 = 2.38, pKa3 = 4.26 pKa4 = 8.60, pKa5 = 10.53 | |||
::::* Solubility in H2O: ca 4,8 gΒ·lβ1 bei 25 Β°C = 12 mM | |||
Β | |||
== DTPA in O2k-FluoRespirometry == | |||
::::* Final concentration in O2k-chamber: 15 Β΅M | |||
::::* Stock solution: |
Revision as of 11:11, 22 August 2017
Description
DTPA (Diethylentriamin-N,N,N',N,N-penta acetic acid, "Triplex V") is a chelator of transition metals, not cell membrane permeable.
Abbreviation: DTPA
Description
- CAS: 67-43-6
- Source: EHERE13095000 VWR 0.25 g
- M: 393,35 g/mol
- Stability constants not included in NIST version of Martell 1989, constants from [1]: Ca2+: 10.74 (EDTA 10.96), Mg2+: 9.3 (EDTA: 8.69) Fe II 16.5 (EDTA 14.3), Fe III 28.6 (EDTA 25.1) Mn II 15.6 (EDTA 14.04), ZN 18.75 (EDTA 16.5), general chelates multivalent ions stronger than EDTA; pKa1 = 2.14, pKa2 = 2.38, pKa3 = 4.26 pKa4 = 8.60, pKa5 = 10.53
- Solubility in H2O: ca 4,8 gΒ·lβ1 bei 25 Β°C = 12 mM
DTPA in O2k-FluoRespirometry
- Final concentration in O2k-chamber: 15 Β΅M
- Stock solution: