Kuka Janis

Name	,
Institution	Latvian Institute of Organic Sythesis
Address	Aizkraukles 21, LV1006
City	Riga
State/Province
Country	Latvia
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Publications

	Published	Reference
Gautam 2023 Neurobiol Dis	2023	Gautam M, Genç B, Helmold B, Ahrens A, Kuka J, Makrecka-Kuka M, Günay A, Koçak N, Aguilar-Wickings IR, Keefe D, Zheng G, Swaminathan S, Redmon M, Zariwala HA, Özdinler PH (2023) SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function. https://doi.org/10.1016/j.nbd.2023.106022
Dambrova 2022 Pharmacol Rev	2022	Dambrova M, Makrecka-Kuka M, Kuka J, Vilskersts R, Nordberg D, Attwood MM, Smesny S, Sen ZD, Guo AC, Oler E, Tian S, Zheng J, Wishart DS, Liepinsh E, Schioth HB. (2022) Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials. https://doi.org/10.1124/pharmrev.121.000408
Liepinsh 2021 Free Radic Biol Med	2021	Liepinsh E, Kuka J, Vilks K, Svalbe B, Stelfa G, Vilskersts R, Sevostjanovs E, Goldins NR, Groma V, Grinberga S, Plaas M, Makrecka-Kuka M, Dambrova M (2021) Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage. Free Radic Biol Med 177:370-80.
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Makrecka-Kuka 2020 Cardiovasc Drugs Ther	2020	Makrecka-Kuka Marina, Korzh Stanislava, Videja Melita, Vilks Karlis, Cirule Helena, Kuka Janis, Dambrova Maija, Liepinsh Edgars (2020) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther 34:791-97.
Makrecka-Kuka 2017 Sci Rep	2017	Makrecka-Kuka M, Sevostjanovs E, Vilks K, Volska K, Antone U, Kuka J, Makarova E, Pugovics O, Dambrova M, Liepinsh E (2017) Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues. Sci Rep 7:17528.
Liepinsh 2016 Biochem J	2016	Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.

Abstracts

	Published	Reference
Volska 2018 MiP2018	2018	The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Kuka 2018 MiP2018	2018	The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
Makrecka-Kuka 2017 Abstract MITOEAGLE Barcelona	2017	Fatty acid oxidation evaluation in mitochondria.
Makrecka-Kuka 2016 Abstract MitoFit Science Camp 2016	2016	Long-chain acylCoAs vs acylcarnitines in mitochondrial bioenergetics: from in vitro to in vivo.
Makrecka 2013 Abstract MiP2013	2013	Makrecka-Kuka M, Volska K, Kuka J, Liepins E, Dambrova M (2013) The accumulation of long chain acyl-carnitines is a major cause of mitochondrial damage during ischemia. Mitochondr Physiol Network 18.08.