LEAK state without adenylates: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=L<sub>N</sub> | |abbr=''L''<sub>N</sub> | ||
|description='''LEAK state without adenylates''' or [[State 2']]. | |description='''LEAK state without adenylates''' or [[State 2']]. | ||
Respiration after addition of substrates, which decreases slowly to the [[LEAK state]] after oxidation of endogenous substrates with no [[adenylate|adenylates]] (L<sub>N</sub>); [[State 2']]. [[State 2]] was re-defined as functionally the same as [[State 4]] (Nicholls and Ferguson 2002), with reference to Chance and Williams (1956). State 2 (Chance and Williams 1955, 1956), however, is substrate-limited residual oxygen consumption at high ADP (ROXD), whereas State 2' (L<sub>N</sub>) and State 4 (L<sub>T</sub>) are LEAK states in the absence of adenylates (L<sub>N</sub>: no ADP, no ATP) or presence of ATP (L<sub>T</sub>). | Respiration after addition of substrates, which decreases slowly to the [[LEAK state]] after oxidation of endogenous substrates with no [[adenylate|adenylates]] (L<sub>N</sub>); [[State 2']]. [[State 2]] was re-defined as functionally the same as [[State 4]] (Nicholls and Ferguson 2002), with reference to Chance and Williams (1956). State 2 (Chance and Williams 1955, 1956), however, is substrate-limited residual oxygen consumption at high ADP (ROXD), whereas State 2' (L<sub>N</sub>) and State 4 (''L''<sub>T</sub>) are LEAK states in the absence of adenylates (''L''<sub>N</sub>: no ADP, no ATP) or presence of ATP (''L''<sub>T</sub>). | ||
|info=[[MiPNet12.15]] | |info=[[MiPNet12.15]] | ||
|type=Respiration | |type=Respiration | ||
}} | }} | ||
{{Labeling}} | {{Labeling | ||
|discipline=Mitochondrial Physiology | |||
|topics=Respiration; OXPHOS; ETS Capacity, Coupling; Membrane Potential, ATP; ADP; AMP; PCr | |||
|instruments=Theory | |||
|type=Respiration | |||
}} |
Revision as of 14:34, 21 October 2010
- high-resolution terminology - matching measurements at high-resolution
LEAK state without adenylates
Description
LEAK state without adenylates or State 2'. Respiration after addition of substrates, which decreases slowly to the LEAK state after oxidation of endogenous substrates with no adenylates (LN); State 2'. State 2 was re-defined as functionally the same as State 4 (Nicholls and Ferguson 2002), with reference to Chance and Williams (1956). State 2 (Chance and Williams 1955, 1956), however, is substrate-limited residual oxygen consumption at high ADP (ROXD), whereas State 2' (LN) and State 4 (LT) are LEAK states in the absence of adenylates (LN: no ADP, no ATP) or presence of ATP (LT).
Abbreviation: LN
Reference: MiPNet12.15
Labels:
Regulation: Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Coupling; Membrane Potential"Coupling; Membrane Potential" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., ATP; ADP; AMP; PCr"ATP; ADP; AMP; PCr" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
HRR: Theory