Semantic search

This page or action requires Javascript to work, please enable Javascript in your browser or use a browser where this is supported so that functionality can be served and is provided as requested. For further assistance, please have a look at the noscript help page.

Search Clear all entries

	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Abid 2020 FASEB J	2020	Abid H, Ryan ZC, Delmotte P, Sieck GC, Lanza IR (2020) Extramyocellular interleukin-6 influences skeletal muscle mitochondrial physiology through canonical JAK/STAT signaling pathways. FASEB J 34:14458-72.	LEAK OXPHOS	N S NS	Intact cells	Mouse	Skeletal muscle
Cubizolle 2020 J Cell Mol Med	2020	Cubizolle A, Cia D, Moine E, Jacquemot N, Guillou L, Rosell M, Angebault-Prouteau C, Lenaers G, Meunier I, Vercauteren J, Durand T, Crauste C, Brabet P (2020) Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal. J Cell Mol Med 24:5057-69.	LEAK OXPHOS ET	N S CIV NS	Permeabilized cells	Rat	Endothelial;epithelial;mesothelial cell
Zhou 2020 Biomed Pharmacother	2020	Zhou J, Zhang Y, Li S, Zhou Q, Lu Y, Shi J, Liu J, Wu Q, Zhou S (2020) Dendrobium nobile Lindl. alkaloids-mediated protection against CCl4-induced liver mitochondrial oxidative damage is dependent on the activation of Nrf2 signaling pathway. Biomed Pharmacother 129:110351.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Liver
Hartmann 2020 Free Radic Res	2020	Hartmann DD, Gonçalves DF, Da Rosa PC, Martins RP, Courtes AA, Franco JL, A Soares FA, Puntel GO (2020) A single muscle contusion promotes an immediate alteration in mitochondrial bioenergetics response in skeletal muscle fibres with different metabolism. Free Radic Res 54:137-49.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Rat	Skeletal muscle
Sharma 2020 Integr Cancer Ther	2020	Sharma P, Singh S (2020) Combinatorial effect of DCA and let-7a on triple-negative MDA-MB-231 cells: A metabolic approach of treatment. Integr Cancer Ther 19:1534735420911437.	LEAK OXPHOS	N S	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Irion 2020 Stem Cells Int	2020	Irion CI, Martins EL, Christie MLA, de Andrade CBV, de Moraes ACN, Ferreira RP, Pimentel CF, Suhett GD, Campos de Carvalho AC, Lindoso RS, Vieyra A, Galina A, Goldenberg RCS (2020) Acute myocardial infarction reduces respiration in rat cardiac fibers, despite adipose tissue mesenchymal stromal cell transplant. Stem Cells Int 2020:4327965 .	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Heart
He 2020 Clin Transl Med	2020	He C, Gao P, Cui Y, Li Q, Li Y, Lu Z, Ma H, Zhao Y, Li L, Sun F, Chen, X, Jia H, Liu D, Yang G, Zheng H, Zhu Z (2020) Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes. Clin Transl Med 10:e205.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Nervous system
Burtscher 2020 eNeuro	2020	Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Chen 2020 Biochim Biophys Acta Mol Basis Dis	2020	Chen T, Hill JT, Moore TM, Cheung ECK, Olsen ZE, Piorczynski TB, Marriott TD, Tessem JS, Walton CM, Bikman BT, Hansen JM, Thomson DM (2020) Lack of skeletal muscle liver kinase B1 alters gene expression, mitochondrial content, inflammation and oxidative stress without affecting high-fat diet-induced obesity or insulin resistance. Biochim Biophys Acta Mol Basis Dis 1866:165805.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Brum 2020 Mol Neurobiol	2020	Brum EDS, Fialho MFP, Fischer SPM, Hartmann DD, Gonçalves DF, Scussel R, Machado-de-Ávila RA, Dalla Corte CL, Soares FAA, Oliveira SM (2020) Relevance of mitochondrial dysfunction in the reserpine-induced experimental fibromyalgia model. Mol Neurobiol 57:4202-17.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Nervous system
Battaglia 2020 Cell Death Dis	2020	Battaglia CR, Cursano S, Calzia E, Catanese A, Boeckers TM (2020) Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons. Cell Death Dis 11:1004.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells	Rat	Nervous system
Jayakumari 2020 J Diabetes	2020	Jayakumari NR, Rajendran RS, Sivasailam A, Vimala SS, Nanda S, Manjunatha S, Pillai VV, Karunakaran J, Gopala S (2020) Impaired substrate-mediated cardiac mitochondrial complex I respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic Asian Indians. J Diabetes 12:542-55.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Human	Heart
Coppin 2020 Cell Death Dis	2020	Coppin L, Jannin A, Ait Yahya E, Thuillier C, Villenet C, Tardivel M, Bongiovanni A, Gaston C, de Beco S, Barois N, van Seuningen I, Durand E, Bonnefond A, Vienne JC, Vamecq J, Figeac M, Vincent A, Delacour D, Porchet N, Pigny P (2020) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death Dis 11:360.	LEAK ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells Intact cells	Human	Islet cell;pancreas;thymus Endothelial;epithelial;mesothelial cell
Hoffmann 2020 J Clin Endocrinol Metab	2020	Hoffmann C, Schneeweiss P, Randrianarisoa E, Schnauder G, Kappler L, Machann J, Schick F, Fritsche A, Heni M, Birkenfeld A, Niess AM, Häring HU, Weigert C, Moller A (2020) Response of mitochondrial respiration in adipose tissue and muscle to 8 weeks of endurance exercise in obese subjects. J Clin Endocrinol Metab 105:dgaa571.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle Fat
Al-Azab 2020 FEBS J	2020	Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X (2020) TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation. FEBS J 287:3088-104.	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Intact cells	Human	Other cell lines
Liu 2020 Am J Physiol Heart Circ Physiol	2020	Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M (2020) Tead1 is essential for mitochondrial function in cardiomyocytes. Am J Physiol Heart Circ Physiol 319:H89-99. https://doi.org/10.1152/ajpheart.00732.2019	LEAK OXPHOS	F N NS	Isolated mitochondria	Mouse	Heart
Hingst 2020 Mol Metab	2020	Hingst JR, Kjøbsted R, Birk JB, Jørgensen NO, Larsen MR, Kido K, Larsen JK, Kjeldsen SAS, Fentz J, Frøsig C, Holm S, Fritzen AM, Dohlmann TL, Larsen S, Foretz M, Viollet B, Schjerling P, Overby P, Halling JF, Pilegaard H, Hellsten Y, Wojtaszewski JFP (2020) Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise. Mol Metab 40:101028.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Severo 2020 Life Sci	2020	Severo L, Godinho D, Machado F, Hartmann D, Fighera MR, Soares FA, Furian AF, Oliveira MS, Royes LF (2020) The role of mitochondrial bioenergetics and oxidative stress in depressive behavior in recurrent concussion model in mice. Life Sci 257:117991.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Deleye 2020 J Biol Chem	2020	Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R (2020) CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway. J Biol Chem 295:17310-22.	LEAK OXPHOS	F N	Homogenate	Mouse	Liver
Pajuelo-Reguera 2020 Cells	2020	Pajuelo Reguera David, Čunátová Kristýna, Vrbacký Marek, Pecinová Alena, Houštěk Josef, Mráček Tomáš, Pecina Petr (2020) Cytochrome c oxidase subunit 4 isoform exchange results in modulation of oxygen affinity. Cells 9:E443.	OXPHOS ET	N S Gp NS Other combinations	Permeabilized cells Oxidase;biochemical oxidation	Human	HEK
Briones-Herrera 2020 Free Radic Biol Med	2020	Briones-Herrera A, Ramírez-Camacho I, Zazueta C, Tapia E, Pedraza-Chaverri J (2020) Altered proximal tubule fatty acid utilization, mitophagy, fission and supercomplexes arrangement in experimental Fanconi syndrome are ameliorated by sulforaphane-induced mitochondrial biogenesis. Free Radic Biol Med 153:54-70.	LEAK OXPHOS	F N S NS ROX	Isolated mitochondria	Rat	Kidney
Davidson 2020 Circ Res	2020	Davidson MT, Grimsrud P, Lai L, Draper J, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM (2020) Extreme acetylation of the cardiac mitochondrial proteome does not promote heart failure. Circ Res 127:1094-108.	LEAK	F N	Isolated mitochondria	Mouse	Heart
McCommis 2020 Nat Metab	2020	McCommis KS, Kovacs A, Weinheimer CJ, Shew TM, Koves TR, Ilkayeva OR, Kamm DR, Pyles KD, King MT, Veech RL, DeBosch BJ, Muoio DM, Gross RW, Finck BN (2020) Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. Nat Metab 2:1232-47. https://doi.org/10.1038/s42255-020-00296-1	LEAK OXPHOS	F N S NS	Permeabilized tissue Isolated mitochondria	Mouse	Heart
Wang 2020 J Mol Med (Berl)	2020	Wang SY, Zhu Siyu, Wu Jian, Zhang Maomao, Xu Yousheng, Xu Wei, Cui Jinjin, Yu Bo, Cao Wei, Liu Jingjin (2020) Exercise enhances cardiac function by improving mitochondrial dysfunction and maintaining energy homoeostasis in the development of diabetic cardiomyopathy. J Mol Med (Berl) 98:245-61.	LEAK OXPHOS	N ROX	Isolated mitochondria	Mouse	Heart
MitoEAGLE muscle 1	2020	Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08	LEAK OXPHOS ET	N NS S ROX	Permeabilized tissue	Human	Skeletal muscle
Boardman 2020 Am J Physiol Heart Circ Physiol	2020	Boardman NT, Pedersen TM, Rossvoll L, Hafstad AD, Aasum E (2020) Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance. Am J Physiol Heart Circ Physiol 319:H682-93.	LEAK OXPHOS	F N	Isolated mitochondria	Mouse	Heart
Baxter 2020 Elife	2020	Baxter M, Voronkov M, Poolman T, Galli G, Pinali C, Goosey L, Knight A, Krakowiak K, Maidstone R, Iqbal M, Zi M, Prehar S, Cartwright EJ, Gibbs J, Matthews LC, Adamson AD, Humphreys NE, Rebelo-Guiomar P, Minczuk M, Bechtold DA, Loudon A, Ray D (2020) Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife 9:e50705.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Heart
Yurre 2020 Arq Bras Cardiol	2020	Yurre AR, Silva JDFD, Torres MKDS, Martins EL, Ramos IP, Silva WSFLD, Sarpa JDS, Guedes CCDS, Napoleão TH, Coelho LCBB, Paiva PMG, Medei E (2020) Evaluation of the cardiac effects of a water-soluble lectin (Wsmol) from Moringa oleifera seeds. Arq Bras Cardiol 114:1029-37.	LEAK OXPHOS	N NS ROX	Isolated mitochondria	Mouse	Heart
Lantier 2020 Diabetes	2020	Lantier Louise, Williams Ashley S, Williams Ian M, Guerin Amanda, Bracy Deanna P, Goelzer Mickael, Foretz Marc, Viollet Benoit, Hughey Curtis C, Wasserman David H (2020) Reciprocity between skeletal muscle AMPK deletion and insulin action in diet-induced obese mice. Diabetes 69:1636-49.	OXPHOS	N	Permeabilized tissue	Mouse	Skeletal muscle
Simard 2020 Metabolites	2020	Simard C, Lebel A, Allain EP, Touaibia M, Hebert-Chatelain E, Pichaud N (2020) Metabolic characterization and consequences of mitochondrial pyruvate carrier deficiency in Drosophila melanogaster. Metabolites 109:E363.	LEAK OXPHOS ET	N S Gp NS ROX	Permeabilized tissue	Drosophila
Politis-Barber 2020 Am J Physiol Endocrinol Metab	2020	Politis-Barber V, Brunetta HS, Paglialunga S, Petrick HL, Holloway GP (2020) Long-term high-fat feeding exacerbates short-term increases in adipose mitochondrial reactive oxygen species, without impairing mitochondrial respiration. Am J Physiol Endocrinol Metab 319:E376-87.	LEAK OXPHOS	F N Gp NS	Permeabilized cells	Mouse	Fat
Lopez 2020 Function (Oxf)	2020	Lopez R, Marzban B, Gao X, Lauinger E, Van den Bergh F, Whitesall SE, Converso-Baran K, Burant CF, Michele DE, Beard DA (2020) Impaired myocardial energetics causes mechanical dysfunction in decompensated failing hearts. Function (Oxf) 1:zqaa018.	LEAK OXPHOS	F N	Isolated mitochondria	Rat	Heart
Li Puma 2020 Am J Physiol Regul Integr Comp Physiol	2020	Li Puma LC, Hedges M, Heckman JM, Mathias AB, Engstrom MR, Brown AB, Chicco AJ (2020) Experimental oxygen concentration influences rates of mitochondrial hydrogen peroxide release from cardiac and skeletal muscle preparations. Am J Physiol Regul Integr Comp Physiol 318:972-80.	LEAK OXPHOS	N NS	Permeabilized tissue Homogenate Isolated mitochondria	Mouse	Heart Skeletal muscle
Weger 2020 Sci Rep	2020	Weger M, Alpern D, Cherix A, Ghosal S, Grosse J, Russeil J, Gruetter R, de Kloet ER, Deplancke B, Sandi C (2020) Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress. Sci Rep 10:18308.	OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Peruzzotti-Jametti 2020 bioRxiv	2020	Peruzzotti-Jametti L, Bernstock JD, Manferrari G, Rogall R, Fernandez-Vizarra E, Williamson JC, Braga A, van den Bosch A, Leonardi T, Kittel A, Benincá C, Vicario N, Tan S, Bastos C, Bicci I, Iraci N, Smith JA, Lehner PJ, Buzas EI, Faria N, Zeviani M, Frezza C, Brisson A, Matheson NJ, Viscomi C, Pluchino S (2020) Neural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells. bioRxiv doi: https://doi.org/10.1101/2020.01.29.923441 .	LEAK	N S Gp CIV ROX	Permeabilized cells	Mouse	Stem cells
Smith 2020 J Biol Chem	2020	Smith CD, Schmidt CA, Lin CT, Fisher-Wellman KH, Neufer PD (2020) Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure. J Biol Chem 295:16207-16.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Skeletal muscle
Cipullo 2020 Nucleic Acids Res	2020	Cipullo M, Pearce SF, Lopez Sanchez IG, Gopalakrishna S, Krüger A, Schober F, Busch JD, Li X, Wredenberg A, Atanassov I, Rorbach J (2020) Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49:354-70.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	HEK
Roginski 2020 Biochim Biophys Acta Mol Basis Dis	2020	Roginski AC, Wajner A, Cecatto C, Wajner SM, Castilho RF, Wajner M, Amaral AU (2020) Disturbance of bioenergetics and calcium homeostasis provoked by metabolites accumulating in propionic acidemia in heart mitochondria of developing rats. Biochim Biophys Acta Mol Basis Dis 1866:165682.	LEAK OXPHOS ET	N S NS	Permeabilized cells Isolated mitochondria Homogenate	Rat	Heart Other cell lines
Schoepf 2020 Nat Commun	2020	Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. https://doi.org/10.1038/s41467-020-15237-5	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Permeabilized tissue	Human	Genital Other cell lines
Makrecka-Kuka 2020 Cardiovasc Drugs Ther	2020	Makrecka-Kuka Marina, Korzh Stanislava, Videja Melita, Vilks Karlis, Cirule Helena, Kuka Janis, Dambrova Maija, Liepinsh Edgars (2020) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther 34:791-97.	OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Heart
Mahalingam 2020 J Physiol	2020	Mahalingam S, Cheviron ZA, Storz JF, McClelland GB, Scott GR (2020) Chronic cold exposure induces mitochondrial plasticity in deer mice native to high altitudes. J Physiol 598:5411-26. https://doi.org/10.1113/JP280298	LEAK OXPHOS	F N S CIV NS	Isolated mitochondria	Mouse	Skeletal muscle
Gvozdjakova 2020 Diagnostics (Basel)	2020	Gvozdjáková A, Sumbalová Z, Kucharská J, Komlósi M, Rausová Z, Vančová O, Számošová M, Mojto V (2020) Platelet mitochondrial respiration, endogenous coenzyme Q₁₀ and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Platelet
Szibor 2020 J Cell Mol Med	2020	Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gaertner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schlueter KD, Jacobs HT(2020) Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. J Cell Mol Med 24:3534-48.	LEAK OXPHOS	N S CIV	Permeabilized tissue Isolated mitochondria	Mouse	Heart
Venediktova 2020 Mitochondrion	2020	Venediktova NI, Mashchenko OV, Talanov EY, Belosludtseva NV, Mironova GD (2020) Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism. Mitochondrion 52:190-96.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Liver
Dawid 2020 Biochim Biophys Acta Bioenerg	2020	Dawid C, Weber D, Musiol E, Janas V, Baur S, Lang R, Fromme T (2020) Comparative assessment of purified saponins as permeabilization agents during respirometry. Biochim Biophys Acta Bioenerg 1861:148251.	LEAK ROUTINE OXPHOS ET	N S Gp NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse	Nervous system HEK
Lensu 2020 Nutrients	2020	Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Lindén J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides ameliorate high-fat-diet-induced hepatic steatosis in rats . Nutrients 12:E3225.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver
Zussman 2020 J Autoimmun	2020	Zussman R, Xu LY, Damani T, Groom KM, Chen Q, Seers B, Viall CA, Chamley LW, Hickey A (2020) Antiphospholipid antibodies can specifically target placental mitochondria and induce ROS production. J Autoimmun 111:102437.	LEAK ET	N S Gp CIV NS ROX	Permeabilized tissue	Human	Genital
Parker 2020 Thesis	2020	Parker EP (2020) The effect of isoleucine supplementation of peripheral blood mononuclear cell metabolism in subjects with type 2 diabetes. URS Thesis 31.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells
Rodriguez 2020 J Gerontol A Biol Sci Med Sci	2020	Rodríguez E, Hakkou M, Hagen TM, Lemieux H, Blier PU (2020) Divergences in the control of mitochondrial respiration are associated with lifespan variation in marine bivalves. J Gerontol A Biol Sci Med Sci 76:796-804.	LEAK OXPHOS ET	F N S Gp CIV ROX	Isolated mitochondria	Molluscs
Xia 2020 Biomed Res Int	2020	Xia W, Wang Q, Lu Y, Hu Y, Zhang X, Zhang J, Liu D, Song J, Zhu Z, Liu D, Zhang H (2020) Transient receptor potential channel canonical type 3 deficiency antagonizes myofibroblast transdifferentiation in vivo. Biomed Res Int 2020:1202189.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Fuchs 2020 J Funct Foods	2020	Fuchs C, Bakuradze T, Steinke R, Grewal R, Eckert GP, Richling E (2020) Polyphenolic composition of extracts from winery by-products and effects on cellular cytotoxicity and mitochondrial functions in HepG2 cells. J Funct Foods 70:103988.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Liver
Chang 2020 J Biol Chem	2020	Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Rodriguez de Yurre 2020 An Acad Bras Cienc	2020	Rodriguez de Yurre A, Martins EGL, Lopez-Alarcon M, Cabral B, Vera N, Lopes JA, Galina A, Takiya CM, Lindoso RS, Vieyra A, SÁenz OC, Medei E (2020) Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model. An Acad Bras Cienc 92:e20191340.	LEAK OXPHOS	N NS ROX	Isolated mitochondria	Mouse	Heart
Tichanek 2020 Sci Rep	2020	Tichanek F, Salomova M, Jedlicka J, Kuncova J, Pitule P, Macanova T, Petrankova Z, Tuma Z, Cendelin J (2020) Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Sci Rep 10:5418.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Keller 2020 Oxid Med Cell Longev	2020	Keller Amy, Hull Sara E, Elajaili Hanan, Johnston Aspen, Knaub Leslie A, Chun Ji hye, Walker Lori, Nozik-Grayck Eva, Reusch Jane EB (2020) (–)-Epicatechin modulates mitochondrial redox in vascular cell models of oxidative stress. Oxid Med Cell Longev 2020:6392629.	LEAK OXPHOS ET	N NS	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Agil 2020 J Clin Med	2020	Agil A, Chayah M, Visiedo L, Navarro-Alarcon M, Rodríguez Ferrer JM, Tassi M, Reiter RJ, Fernández-Vázquez G (2020) Melatonin improves mitochondrial dynamics and function in the kidney of Zücker diabetic fatty rats. J Clin Med 9:E2916.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Kidney
Kuzniewska 2020 EMBO Rep	2020	Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M (2020) Mitochondrial protein biogenesis in the synapse is supported by local translation. EMBO Rep 21:e48882.	LEAK ET	N S	Permeabilized cells	Human Mouse	Nervous system HEK
Kamarauskaite 2020 Biomed Res Int	2020	Kamarauskaite J, Baniene R, Trumbeckas D, Strazdauskas A, Trumbeckaite S (2020) Increased succinate accumulation induces ROS generation in in vivo ischemia/reperfusion-affected rat kidney mitochondria. Biomed Res Int 2020:8855585.	LEAK OXPHOS	N S		Rat	Kidney
Frambach 2020 Biochim Biophys Acta Mol Basis Dis	2020	Frambach SJCM, van de Wal MAE, van den Broek PHH, Smeitink JAM, Russel FGM, de Haas R, Schirris TJJ (2020) Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165727.	LEAK OXPHOS	F N S Gp CIV Other combinations ROX	Permeabilized tissue	Mouse	Skeletal muscle
Mahul-Mellier 2020 Proc Natl Acad Sci U S A	2020	Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Mouse	Nervous system
Ulgherait 2020 Nat Commun	2020	Ulgherait Matt, Chen Anna, McAllister Sophie F, Kim Han X, Delventhal Rebecca, Wayne Charlotte R, Garcia Christian J, Recinos Yocelyn, Oliva Miles, Canman Julie C, Picard Martin, Owusu-Ansah Edward, Shirasu-Hiza Mimi (2020) Circadian regulation of mitochondrial uncoupling and lifespan. Nat Commun 11:1927.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Drosophila
Courtes 2020 Brain Res Bull	2020	Courtes AA, Gonçalves DF, Hartmann DD, da Rosa PC, Cassol G, Royes LFF, de Carvalho NR, Soares FAA (2020) Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injury. Brain Res Bull 163:31-39.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Kunz 2020 J Biol Chem	2020	Kunz HE, Dorschner JM, Berent TE, Meyer T, Wang X, Jatoi A, Kumar R, Lanza IR (2020) Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting. J Biol Chem 295:17441-59.	LEAK ROUTINE OXPHOS ET	N NS ROX S	Permeabilized tissue Intact cells	Mouse	Skeletal muscle
Monaco 2020 Am J Physiol Endocrinol Metab	2020	Monaco CMF, Bellissimo CA, Hughes MC, Ramos SV, Laham R, Perry CGR, Hawke TJ (2020) Sexual dimorphism in human skeletal muscle mitochondrial bioenergetics in response to type 1 diabetes. Am J Physiol Endocrinol Metab 318:E44-E51.	OXPHOS	N S	Permeabilized tissue	Human	Skeletal muscle
Brand 2020 J Clin Med	2020	Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.	LEAK OXPHOS ET	N CIV ROX	Permeabilized cells	Human	Lymphocyte
Jian 2020 Cell Metab	2020	Jian C, Fu J, Cheng X, Shen LJ, Ji YX, Wang X, Pan S, Tian H, Tian S, Liao R, Song K, Wang HP, Zhang X, Wang Y, Huang Z, She ZG, Zhang XJ, Zhu L, Li H (2020) Low-dose sorafenib acts as a mitochondrial uncoupler and ameliorates nonalcoholic steatohepatitis. Cell Metab 31:892-908. https://doi.org/10.1016/j.cmet.2020.04.011	LEAK OXPHOS ET	N S CIV ROX	Permeabilized cells	Mouse	Liver
Guo 2020 Hum Gene Ther	2020	Guo Y, Zhang K, Gao X, Zhou Z, Liu Z, Yang K, Huang K, Yang Q, Long Q (2020) Sustained oligomycin sensitivity conferring protein expression in cardiomyocytes protects against cardiac hypertrophy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Heart
Baggio 2020 Neurotoxicology	2020	Baggio S, Zenki K, Martins Silva A, Dos Santos TG, Rech G, Lazzarotto G, Dias RD, Mussulini BH, Rico EP, de Oliveira DL (2020) Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish. Neurotoxicology 78:152-160.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Zebrafish	Nervous system
Fisher 2020 Placenta	2020	Fisher J, McKeating D, Pennell E, Cuffe J, Holland O, Perkins A (2020) Mitochondrial isolation, cryopreservation and preliminary biochemical characterisation from placental cytotrophoblast and syncytiotrophoblast. Placenta 82:1-4.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Human	Genital
Mikulas 2020 Materials	2020	Mikulás K, Komlódi T, Földes A, Sváb G, Horváth G, Nagy AM, Ambrus A, Gyulai-Gaál Sz, Gera I, Hermann P, Varga G, Tretter L (2020) Bioenergetic Impairment of triethylene glycol dimethacrylate- (TEGDMA-) treated dental pulp stem cells (DPSCs) and isolated brain mitochondria are amended by redox compound methylene blue. Materials (Basel) 13(16):3472.	OXPHOS ET ROUTINE	N S ROX	Isolated mitochondria Permeabilized cells Intact cells	Guinea pig Human	Stem cells
Falcao-Tebas 2020 J Physiol	2020	Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK (2020) Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol 598:4251-70.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Chandramouleeswaran 2020 PLoS One	2020	Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H (2020) Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PLoS One 15:e0239625.	ROUTINE OXPHOS	N S CIV ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell
Grewal 2020 Exp Neurol	2020	Grewal R, Reutzel M, Dilberger B, Hein H, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C, Eckert GP (2020) Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol 328:113248.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Neuroblastoma
Carvalho 2020 BMC Nutr	2020	Carvalho E, Adams SH, Borsheim E, Blackburn ML, Ono-Moore KD, Cotter M, Bowlin AK, Yeruva L (2020) Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk. BMC Nutr 6:13.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Pig	Liver
Edmunds 2020 Mol Metab	2020	Edmunds LR, Xie B, Mills AM, Huckestein BR, Undamatla R, Murali A, Pangburn MM, Martin J, Sipula I, Kaufman BA, Scott I, Jurczak MJ (2020) Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance. Mol Metab 41:101051.	LEAK OXPHOS ET	F N ROX	Homogenate	Mouse	Liver
Risiglione 2020 Int J Mol Sci	2020	Risiglione P, Leggio L, Cubisino SAM, Reina S, Paternò G, Marchetti B, Magrì A, Iraci N, Messina A (2020) High-resolution respirometry reveals MPP⁺ mitochondrial toxicity mechanism in a cellular model of parkinson's disease. Int J Mol Sci 21:E7809. https://doi.org/10.3390/ijms21217809	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Neuroblastoma
McLaughlin 2020 Sci Rep	2020	McLaughlin KL, Kew KA, McClung JM, Fisher-Wellman KH (2020) Subcellular proteomics combined with bioenergetic phenotyping reveals protein biomarkers of respiratory insufficiency in the setting of proofreading-deficient mitochondrial polymerase. Sci Rep 10:3603.	LEAK	F N S	Isolated mitochondria	Mouse	Heart Skeletal muscle
Sowton 2020 Mol Genet Metab Rep	2020	Sowton AP, Padmanabhan N, Tunster SJ, McNally BD, Murgia A, Yusuf A, Griffin JL, Murray AJ, Watson ED (2020) Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice. Mol Genet Metab Rep 23:100580.	LEAK OXPHOS	N NS	Homogenate	Mouse	Liver
Heinonen 2020 Sci Rep	2020	Heinonen I, Sorop O, van Dalen BM, Wüst RCI, van de Wouw J, de Beer VJ, Octavia Y, van Duin RWB, Hoogstrate Y, Blonden L, Alkio M, Anttila K, Stubbs A, van der Velden J, Merkus D, Duncker DJ (2020) Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement. Sci Rep 10:13173.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Pig	Heart
Gnaiger 2020 BEC MitoPathways	2020	Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5^th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells	Human Mouse	Heart Skeletal muscle Fibroblast
Cecatto 2020 Mitochondrion	2020	Cecatto C, Amaral AU, Wajner A, Wajner SM, Castilho RF, Wajner M (2020) Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats. Mitochondrion 50:1-13.	LEAK OXPHOS ET	N S	Permeabilized cells Isolated mitochondria	Rat	Liver Other cell lines
Larsen 2020 Acta Physiol (Oxf)	2020	Larsen FJ, Schiffer TA, Zinner C, Willis SJ, Morales-Alamo D, Calbet J, Boushel R, Holmberg HC (2020) Mitochondrial oxygen affinity increases after sprint interval training and is related to the improvement in peak oxygen uptake. https://doi.org/10.1111/apha.13463	OXPHOS	N NS	Isolated mitochondria	Human	Skeletal muscle
Bhaskaran 2020 Aging Cell	2020	Bhaskaran S, Pollock N, C Macpherson P, Ahn B, Piekarz KM, Staunton CA, Brown JL, Qaisar R, Vasilaki A, Richardson A, McArdle A, Jackson MJ, Brooks SV, Van Remmen H (2020) Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. Aging Cell 19:e13225.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
De-Souza 2020 J Biol Chem	2020	De-Souza EA, Pimentel FSA, De-Queiroz ALFV, Camara H, Felix-Formiga ML, Machado CM, Pinto S, Galina A, Mori MA, Montero-Lomelí M, Masuda CA (2020) The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response. J Biol Chem 295:3773-82.	LEAK OXPHOS	N Gp NS ROX	Isolated mitochondria Intact cells	Caenorhabditis elegans Saccharomyces cerevisiae
Rebane-Klemm 2020 Cancers (Basel)	2020	Rebane-Klemm E, Truu L, Reinsalu L, Puurand M, Shevchuk I, Chekulayev V, Timohhina N, Tepp K, Bogovskaja J, Afanasjev V, Suurmaa K, Valvere V, Kaambre T (2020) Mitochondrial respiration in KRAS and BRAF mutated colorectal tumors and polyps. Cancers (Basel) 12:E815.	LEAK OXPHOS	N NS	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Ehrlicher 2020 FASEB J	2020	Ehrlicher SE, Stierwalt HD, Miller BF, Newsom SA, Robinson MM (2020) Mitochondrial adaptations to exercise do not require Bcl2-mediated autophagy but occur with BNIP3/Parkin activation. FASEB J 34:4602-18.	LEAK OXPHOS ET	F N S NS	Isolated mitochondria	Mouse	Skeletal muscle
Song 2020 Life Sci	2020	Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633.	LEAK OXPHOS ET	F N NS	Homogenate	Mouse	Liver
Pereira 2020 PLoS One	2020	Pereira GC, Lee L, Rawlings N, Ouwendijk J, Parker JE, Andrienko TN, Henley JM, Halestrap AP (2020) Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia. PLoS One 15:e0234653.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Hroudova 2020 Mol Neurobiol	2020	Hroudová J, Nováková T, Korábečný J, Maliňák D, Górecki L, Fišar Z (2020) Effects of novel tacrine derivatives on mitochondrial energy metabolism and monoamine oxidase activity-in vitro study. Mol Neurobiol 58:1102-13.	OXPHOS	N S ROX	Isolated mitochondria	Pig	Nervous system
Szibor 2020 J Biol Chem	2020	Szibor Marten, Gizatullina Zemfira, Gainutdinov Timur, Endres Thomas, Debska-Vielhaber Grazyna, Kunz Matthias, Karavasili Niki, Hallmann Kerstin, Schreiber Frank, Bamberger Alexandra, Schwarzer Michael, Doenst Torsten, Heinze Hans-Jochen, Leßmann Volkmar, Vielhaber Stefan, Kunz Wolfram S, Gellerich Frank Norbert (2020) Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply. J Biol Chem 295:4383-97.	LEAK OXPHOS	N S Gp CIV NS ROX	Isolated mitochondria Intact cells	Mouse	Nervous system
Feng 2020 Int J Biol Macromol	2020	Feng Q, Shao M, Han J, Tang T, Zhang Y, Liu F (2020) TFAM, a potential oxidative stress biomarker used for monitoring environment pollutants in Musca domestica. Int J Biol Macromol 155:524-34.	LEAK OXPHOS	N S ROX	Isolated mitochondria	Hexapods
Belosludtsev 2020 Biochimie	2020	Belosludtsev KN, Belosludtseva NV, Kosareva EA, Talanov EY, Gudkov SV, Dubinin MV (2020) Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver mitochondria. Biochimie 176:150-57.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Rat	Liver
Wen 2020 Biomedicines	2020	Wen JJ, Cummins CB, Williams TP, Radhakrishnan RS (2020) The genetic evidence of burn-induced cardiac mitochondrial metabolism dysfunction . Biomedicines 8:E566.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Rat	Heart
Zhang 2020 Chemosphere	2020	Zhang Y, Li Y, Feng Q, Shao M, Yuan F, Liu F (2020) Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae. Chemosphere 248:126009.	LEAK OXPHOS	N S ROX	Isolated mitochondria	Hexapods
Alexopoulos 2020 Nat Commun	2020	Alexopoulos SJ, Chen SY, Brandon AE, Salamoun JM, Byrne FL, Garcia CJ, Beretta M, Olzomer EM, Shah DP, Philp AM, Hargett SR, Lawrence RT, Lee B, Sligar J, Carrive P, Tucker SP, Philp A, Lackner C, Turner N, Cooney GJ, Santos WL, Hoehn KL (2020) Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice. Nat Commun 11:2397.	LEAK	N	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver Fat
Magnesa 2020 Thesis	2020	Magnesa B (2020) Skeletal muscle mitochondrial oxidative phosphorylation plasticity in two studies on humans: exercise training effect in obese subjects and bed rest effect in healthy subjects. PhD Thesis 81.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Nascimento-Dos-Santos 2020 Biochim Biophys Acta Mol Basis Dis	2020	Nascimento-Dos-Santos G, de-Souza-Ferreira E, Lani R, de Faria CC, Araujo VG, Teixeira-Pinheiro LC, de Souza Vasconcelos T, Leandro TG, Santiago MF, Linden R, Galina A, Petrs-Silva H (2020) Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. Biochim Biophys Acta Mol Basis Dis 1866:165686.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Isolated mitochondria Intact cells	Rat	Liver Nervous system
Vaccari 2020 Eur J Appl Physiol	2020	Vaccari F, Passaro A, D'Amuri A, Sanz JM, Di Vece F, Capatti E, Magnesa B, Comelli M, Mavelli I, Grassi B, Fiori F, Bravo G, Avancini A, Parpinel M, Lazzer S (2020) Effects of 3-month high-intensity interval training vs. moderate endurance training and 4-month follow-up on fat metabolism, cardiorespiratory function and mitochondrial respiration in obese adults. Eur J Appl Physiol 120:1787-803.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Rodrigues 2020 J Appl Physiol (1985)	2020	Rodrigues GC, Rocha NN, Maia LA, Melo I, Simões AC, Antunes MA, Bloise FF, Woyames J, da-Silva WS, Capelozzi VL, Abela G, Ball L, Pelosi P, Rocco PRM, Silva PL (2020) Impact of experimental obesity on diaphragm structure, function and bioenergetics. J Appl Physiol (1985) 129:1062-74.	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue	Rat	Skeletal muscle
Pena 2020 Int J Chronic Dis	2020	Pena GS, Paez HG, Johnson TK, Halle JL, Carzoli JP, Visavadiya NP, Zourdos MC, Whitehurst MA, Khamoui AV (2020) Hippocampal growth factor and myokine cathepsin B expression following aerobic and resistance training in 3xTg-AD mice. Int J Chronic Dis 2020:Article ID 5919501.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Eshima 2020 J Appl Physiol (1985)	2020	Eshima H, Siripoksup P, Mahmassani ZS, Johnson JM, Ferrara PJ, Verkerke ARP, Salcedo A, Drummond MJ, Funai K (2020) Neutralizing mitochondrial ROS does not rescue muscle atrophy induced by hindlimb unloading in female mice. J Appl Physiol (1985) 129:124-32.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Skeletal muscle
Bose 2020 Aging Cell	2020	Bose C, Alves I, Singh P, Palade PT, Carvalho E, Børsheim E, Jun SR, Cheema A, Boerma M, Awasthi S, Singh SP (2020) Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell 19:e13261.	LEAK OXPHOS	F N CIV NS ROX	Permeabilized tissue	Mouse	Heart
Hafstad 2020 Antioxidants (Basel)	2020	Hafstad AD, Hansen SS, Lund J, Santos CXC, Boardman NT, Shah AM, Aasum E (2020) NADPH oxidase 2 mediates myocardial oxygen wasting in obesity. Antioxidants (Basel) 9:E171.	LEAK OXPHOS	F N	Isolated mitochondria	Mouse	Heart
MitoEAGLE blood cells 1	2020	Åsander Frostner Eleonor, Aburel Oana M, Avram Vlad F, Calabria Elisa, Castelo Rueda Maria Paulina, Chamkha Imen, Čižmárová Beata, Danila Maria-Daniela, Doerrier Carolina, Eckert Gunter P, Ehinger Johannes K, Elmer Eskil, Garcia-Souza Luiz F, Gnaiger Erich, Hoppel Florian, Karabatsiakis Alexander, Keppner Gloria, Kidere Dita, Krako Jakovljević Nina, Labieniec-Watala Magdalena, Lelcu Theia, Micankova Petra, Michalak Slawomir, Molina Anthony JA, Pavlovic Kasja, Pichler Irene, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina, Silaidos Carmina, Sjövall Fredrik, Sobotka Ondrej, Sumbalova Zuzana, Swiniuch Daria, Vernerova Andrea, Volani Chiara, Vujacic-Mirski Ksenija, Watala Cezary (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS Other combinations ROX	Intact cells Permeabilized cells	Human	Blood cells Platelet
Burtscher 2020 Int J Mol Sci	2020	Burtscher J, Di Pardo A, Maglione V, Schwarzer C, Squitieri F (2020) Mitochondrial respiration changes in R6/2 Huntington's Disease model mice during aging in a brain region specific manner. Int J Mol Sci 21:5412.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Matsuo 2020 Am J Physiol Endocrinol Metab	2020	Matsuo FS, Araújo PHC, Mota RF, Carvalho AJR, Queiroz MS, Almeida BB, Ferreira KCOS, Metzner RJM, Ferrari GD, Alberici LC, Osako MK (2020) RANKL induces beige adipocyte differentiation in preadipocytes. Am J Physiol Endocrinol Metab 318:E866-77.	LEAK OXPHOS	N	Permeabilized cells	Mouse	Fat
Weber 2020 FASEB J	2020	Weber M, Mera P, Casas J, Salvador J, Rodríguez A, Alonso S, Sebastián D, Soler-Vázquez MC, Montironi C, Recalde S, Fucho R, Calderón-Domínguez M, Mir JF, Bartrons R, Escola-Gil JC, Sánchez-Infantes D, Zorzano A, Llorente-Cortes V, Casals N, Valentí V, Frühbeck G, Herrero L, Serra D (2020) Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD. FASEB J 34:11816-37.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Liver
Contreras Mostazo 2020 Cancers (Basel)	2020	Mostazo MGC, Kurrle N, Casado M, Fuhrmann D, Alshamleh I, Häupl B, Martín-Sanz P, Brüne B, Serve H, Schwalbe H, Schnütgen F, Marin S, Cascante M (2020) Metabolic plasticity is an essential requirement of acquired tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Cancers (Basel) 12:E3443.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV ROX	Permeabilized cells Intact cells	Human	Blood cells
Skemiene 2020 J Bioenerg Biomembr	2020	Skemiene K, Pampuscenko K, Rekuviene E, Borutaite V (2020) Protective effects of anthocyanins against brain ischemic damage. J Bioenerg Biomembr 52:71-82.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Nervous system
Buch 2020 FASEB J	2020	Buch BT, Halling JF, Ringholm S, Gudiksen A, Kjøbsted R, Olsen MA, Wojtaszewski JFP, Pilegaard H (2020) Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. FASEB J 34:8653-70.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Visavadiya 2020 Mol Cell Biochem	2020	Visavadiya NP, Pena GS, Khamoui AV (2020) Mitochondrial dynamics and quality control are altered in a hepatic cell culture model of cancer cachexia. Mol Cell Biochem 476:23-34.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Mouse	Liver
Purhonen 2020 Nat Commun	2020	Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, Kallijärvi J (2020) A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Nat Commun 11:322.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Liver Kidney
Bloise 2020 Thyroid	2020	Bloise FF, Santos AT, Brito JT, Andrade CBV, Oliveira TS, Souza AF, Fontes KN, Silva JD, Blanco NG, Silva PL, Rocco PRM, Fliers E, Boelen A, da-Silva WS, Ortiga-Carvalho TM (2020) Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse diaphragm. Thyroid 30:1079-90.	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue	Mouse	Skeletal muscle
Barsottini 2020 Commun Biol	2020	Barsottini MRO, Copsey A, Young L, Baroni RM, Cordeiro AT, Pereira GAG, Moore AL (2020) Biochemical characterization and inhibition of the alternative oxidase enzyme from the fungal phytopathogen Moniliophthora perniciosa. Commun Biol 3:263.	OXPHOS	F N S CIV		Protists
Musi 2020 Aging Cell	2020	Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2020) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Hardee 2020 Mol Metab	2020	Hardee JP, Martins KJB, Miotto PM, Ryall JG, Gehrig SM, Reljic B, Naim T, Chung JD, Trieu J, Swiderski K, Philp AM, Philp A, Watt MJ, Stroud DA, Koopman R, Steinberg GR, Lynch GS (2020) Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity. Mol Metab 45:101157.	OXPHOS LEAK	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Dulac 2020 J Physiol	2020	Dulac M, Leduc-Gaudet JP, Reynaud O, Ayoub MB, Guérin A, Finkelchtein M, Hussain SN, Gouspillou G (2020) Drp1 knockdown induces severe muscle atrophy and remodelling, mitochondrial dysfunction, autophagy impairment and denervation . J Physiol 598:3691-710.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Avila-Rojas 2020 Food Chem Toxicol	2020	Avila-Rojas SH, Aparicio-Trejo OE, Briones-Herrera A, Medina-Campos ON, Reyes-Fermín LM, Martínez-Klimova E, León-Contreras JC, Hernández-Pando R, Tapia E, Pedraza-Chaverri J (2020) Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin. Food Chem Toxicol 145:111774.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Kidney
Cornelissen 2020 Hum Mol Genet	2020	Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W (2020) CHCHD2 harboring the Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet 29:1096-106.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Fibroblast
Silaidos 2020 Mitochondrion	2020	Silaidos C, Grube J, Muley C, Eckert GP (2020) Time-dependent melatonin secretion is associated with mitochondrial function in peripheral blood mononuclear cells (PBMC) of male volunteers. Mitochondrion 53:21-29.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells
Wefers 2020 Mol Metab	2020	Wefers J, Connell NJ, Fealy CE, Andriessen C, de Wit V, van Moorsel D, Moonen-Kornips E, Jörgensen JA, Hesselink MKC, Havekes B, Hoeks J, Schrauwen P (2020) Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals. Mol Metab 41:101050.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Palavicini 2020 JCI Insight	2020	Palavicini JP, Chen J, Wang C, Wang J, Qin C, Baeuerle E, Wang X, Woo JA, Kang DE, Musi N, Dupree JL, Han X (2020) Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes. JCI Insight 5:137286.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Nervous system
Groennebaek 2020 Cells	2020	Groennebaek T, Billeskov TB, Schytz CT, Jespersen NR, Bøtker HE, Olsen RKJ, Eldrup N, Nielsen J, Farup J, De Paoli FV, Vissing K (2020) Mitochondrial structure and function in the metabolic myopathy accompanying patients with critical limb ischemia. Cells 9:E570.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Reutzel 2020 Oxid Med Cell Longev	2020	Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769.	LEAK ET OXPHOS	N S CIV ROX	Isolated mitochondria	Mouse	Nervous system
Larsen 2020 Cardiovasc Drugs Ther	2020	Larsen AH, Wiggers H, Dollerup OL, Jespersen NR, Hansson NH, Frøkiær J, Brøsen K, Nørrelund H, Bøtker HE, Møller N, Jessen N (2020) Metformin lowers body weight but fails to increase insulin sensitivity in chronic heart failure patients without diabetes: a randomized, double-blind, placebo-controlled study. Cardiovasc Drugs Ther 35:491-503.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Oellermann 2020 Sci Rep	2020	Oellermann M, Hickey AJR, Fitzgibbon QP, Smith G (2020) Thermal sensitivity links to cellular cardiac decline in three spiny lobsters. Sci Rep 10:202.	LEAK OXPHOS ET	N S NS	Homogenate	Crustaceans	Heart
Khamoui 2020 Physiol Genomics	2020	Khamoui AV, Tokmina-Roszyk D, Rossiter HB, Fields GB, Visavadiya NP (2020) Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. Physiol Genomics 52:203-16.	LEAK OXPHOS ET	N NS	Intact cells	Mouse	Liver
Brunetta 2020 J Physiol	2020	Brunetta HS, Politis-Barber V, Petrick HL, Dennis KMJH, Kirsh AJ, Barbeau PA, Nunes EA, Holloway GP (2020) Nitrate attenuates HFD-induced glucose intolerance in association with reduced epididymal adipose tissue inflammation and mitochondrial ROS emission. J Physiol 598:3357-71.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Fat
Bundgaard 2020 J Exp Biol	2020	Bundgaard A, Qvortrup K, Rasmussen LJ, Fago A (2020) Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia. J Exp Biol 222:jeb200410.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Amphibians	Heart
Duong 2020 Mitochondrion	2020	Duong QV, Hoffman A, Zhong K, Dessinger MJ, Zhang Y, Bazil JN (2020) Calcium overload decreases net free radical emission in cardiac mitochondria. Mitochondrion 51:126-39.	LEAK OXPHOS ET	F N S	Isolated mitochondria	Guinea pig	Heart
Kanellopoulos 2020 Cell	2020	Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Drosophila	Nervous system Other cell lines
Lensu 2020 Preprints	2020	Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Linden J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides targeting Faecalibacterium prausnitzii prevent high fat diet-induced hepatic steatosis in rats. Preprints 2020:2020090241.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver
Ost 2020 EMBO Rep	2020	Ost M, Igual Gil C, Coleman V, Keipert S, Efstathiou S, Vidic V, Weyers M, Klaus S (2020) Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Cecatto 2020 Toxicol In Vitro	2020	Cecatto C, Amaral AU, Roginski AC, Castilho RF, Wajner M (2020) Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy. Toxicol In Vitro 62:104665.	LEAK OXPHOS ET	N S	Permeabilized tissue Isolated mitochondria	Rat	Skeletal muscle
Woodhead 2020 J Appl Physiol (1985)	2020	Woodhead JST, D'Souza RF, Hedges CP, Wan J, Berridge MV, Cameron-Smith D, Cohen P, Hickey AJR, Mitchell CJ, Merry TL (2020) High-intensity interval exercise increases humanin, a mitochondrial encoded peptide, in the plasma and muscle of men. J Appl Physiol (1985) 128:1346-54.	OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Jespersen 2020 Sci Rep	2020	Jespersen NR, Hjortbak MV, Lassen TR, Støttrup NB, Johnsen J, Tonnesen PT, Larsen S, Kimose HH, Bøtker HE (2020) Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus. Sci Rep 10:10344.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Rat	Heart
McLaughlin 2020b Sci Rep	2020	McLaughlin KL, Hagen JT, Coalson HS, Nelson MAM, Kew KA, Wooten AR, Fisher-Wellman KH (2020) Novel approach to quantify mitochondrial content and intrinsic bioenergetic efficiency across organs. Sci Rep 10:17599.	LEAK OXPHOS ET	F N S Gp CIV ROX	Isolated mitochondria	Mouse	Heart Liver Kidney Fat
Bertero 2020 Circ Res	2020	Bertero E, O'Rourke B, Maack C (2020) Mitochondria do not survive calcium overload during transplantation. Circ Res 126:784-86.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Gvozdjakova 2020 Can J Physiol Pharmacol	2020	Gvozdjakova A, Kucharska J, Kura B, Vancova O, Rausova Z, Sumbalova Z, Ulicna O, Slezak J (2020) A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. Can J Physiol Pharmacol 98: 29–34. doi: 10.1139/cjpp-2019-0281.		N S		Rat	Heart
Hassan 2020 MitoFit Preprint Arch	2020	Hassan Hazirah, Gnaiger Erich, Zakaria Fazaine, Makpol Suzana, Abdul Karim Norwahidah (2020) Alterations in mitochondrial respiratory capacity and membrane potential: a link between mitochondrial dysregulation and autism. https://doi.org/10.26124/mitofit:200003	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human
Pelster 2020 PLoS One	2020	Pelster B, Wood CM, Campos DF, Val AL (2020) Cellular oxygen consumption, ROS production and ROS defense in two different size-classes of an Amazonian obligate air-breathing fish (Arapaima gigas). PLoS One 15:e0236507.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Kidney Lung;gill
Makrecka-Kuka 2020 Sci Rep	2020	Makrecka-Kuka M, Dimitrijevs P, Domracheva I, Jaudzems K, Dambrova M, Arsenyan P (2020) Fused isoselenazolium salts suppress breast cancer cell growth by dramatic increase in pyruvate-dependent mitochondrial ROS production. https://doi.org/10.1038/s41598-020-78620-8.	LEAK OXPHOS	N S NS ROX	Permeabilized cells	Mouse	Endothelial;epithelial;mesothelial cell
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1	LEAK OXPHOS ET	F N S Gp DQ CIV NS Other combinations ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria
Hosmann 2020 Acta Neurochir (Wien)	2020	Hosmann A, Milivojev N, Dumitrescu S, Reinprecht A, Weidinger A, Kozlov AV (2020) Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach. Acta Neurochir (Wien) 163:139-49.	OXPHOS	N S CIV ROX	Homogenate	Rat	Nervous system
Esselun 2020 Neuromolecular Med	2020	Esselun C, Dilberger B, Silaidos CV, Koch E, Schebb NH, Eckert GP (2020) A walnut diet in combination with enriched environment improves cognitive function and affects lipid metabolites in brain and liver of aged NMRI mice. Neuromolecular Med 23:140-60.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Tepp 2020 Biochim Biophys Acta Gen Subj	2020	Tepp K, Puurand M, Timohhina N, Aid-Vanakova J, Reile I, Shevchuk I, Chekulayev V, Eimre M, Peet N, Kadaja L, Paju K, Kaambre T (2020) Adaptation of striated muscles to Wolframin deficiency in mice: Alterations in cellular bioenergetics. Biochim Biophys Acta Gen Subj 1864:129523.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Mouse	Heart Skeletal muscle
Hayes 2020 Nutrients	2020	Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871.	LEAK ROUTINE OXPHOS ET	N S Gp CIV ROX	Permeabilized cells Intact cells	Human	HeLa
Rondot 2020 Thesis	2020	Rondot A (2020) Fuels for winter: the role of proline in overwintering bumblebee queens (Bombus impatiens). Master's Thesis 41.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Hexapods	Skeletal muscle
MiPNet18.05 Amplex-Mouse-heart	2019-06-24	O2k-Fluorometry: HRR and H₂O₂ production in mouse cardiac tissue homogenate.	LEAK OXPHOS ET	N S NS	Homogenate	Mouse	Heart
Altinok 2019 J Cell Physiol	2019	Altinok O, Poggio JL, Stein DE, Bowne WB, Shieh AC, Snyder NW, Orynbayeva Z (2019) Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria. J Cell Physiol 235:2569-81.	LEAK OXPHOS	N S	Isolated mitochondria	Human	Other cell lines
Lewis 2019 Am J Physiol Regul Integr Comp Physiol	2019	Lewis MT, Kasper JD, Bazil JN, Frisbee JC, Wiseman RW (2019) Skeletal muscle energetics are compromised only during high-intensity contractions in the Goto-Kakizaki rat model of type 2 diabetes. Am J Physiol Regul Integr Comp Physiol 317:R356-68.	LEAK OXPHOS	F N	Isolated mitochondria	Rat	Skeletal muscle
McManus 2019 Cell Metab	2019	McManus MJ, Picard M, Chen HW, De Haas HJ, Potluri P, Leipzig J, Towheed A, Angelin A, Sengupta P, Morrow RM, Kauffman BA, Vermulst M, Narula J, Wallace DC (2019) Mitochondrial DNA variation dictates expressivity and progression of nuclear DNA mutations causing cardiomyopathy. Cell Metab 29:78-90.	LEAK OXPHOS	N ROX	Isolated mitochondria	Mouse	Heart
Dlaskova 2019 Biochim Biophys Acta Bioenerg	2019	Dlasková A, Špaček T, Engstová H, Špačková J, Schröfel A, Holendová B, Smolková K, Plecitá-Hlavatá L, Ježek P (2019) Mitochondrial cristae narrowing upon higher 2-oxoglutarate load. Biochim Biophys Acta Bioenerg 1860:659-78.	LEAK ET	N ROX	Intact cells	Human	Liver
Cornacchia 2019 Cell Stem Cell	2019	Cornacchia D, Zhang C, Zimmer B, Chung SY, Fan Y, Soliman MA, Tchieu J, Chambers SM, Shah H, Paull D, Konrad C, Vincendeau M, Noggle SA, Manfredi G, Finley LWS, Cross JR, Betel D, Studer L (2019) Lipid deprivation induces a stable, naive-to-primed intermediate state of pluripotency in human PSCs. Cell Stem Cell 25:120-36.	LEAK ET	N CIV	Intact cells	Human	Stem cells
Hunter 2019 J Appl Physiol	2019	Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between V̇o2peak, cycle economy, and mitochondrial respiration in untrained/trained. J Appl Physiol 127:1562-8.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Skeletal muscle
Bettinazzi 2019 Proc Biol Sci	2019	Bettinazzi S, Rodríguez E, Milani L, Blier PU, Breton S (2019) Metabolic remodelling associated with mtDNA: insights into the adaptive value of doubly uniparental inheritance of mitochondria. Proc Biol Sci 286:20182708.	LEAK OXPHOS ET	N Gp CIV NS ROX	Permeabilized cells	Molluscs	Lung;gill Genital
Sundstroem 2019 Acta Neuropathol Commun	2019	Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Bahador M, Bernatz S, Braun Y, Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam S, Tepper CG, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen F (2019) Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis. Acta Neuropathol Commun 7:55.	ET LEAK	N S NS ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Germain 2019 Int J Med Sci	2019	Germain N, Dessein AF, Vienne JC, Dobbelaere D, Mention K, Joncquel M, Dekiouk S, Laine W, Kluza J, Marchetti P (2019) First-line screening of OXPHOS deficiencies using microscale oxygraphy in human skin fibroblasts: A preliminary study. Int J Med Sci 16:931-38.	LEAK ET	ROX N	Intact cells	Human	Fibroblast
Wolf 2019 Cells	2019	Wolf C, Zimmermann R, Thaher O, Bueno D, Wüllner V, Schäfer MKE, Albrecht P, Methner A (2019) The Charcot-Marie tooth disease mutation R94Q in MFN2 decreases ATP production but increases mitochondrial respiration under conditions of mild oxidative stress. Cells 8:E1289.	LEAK ROUTINE ET OXPHOS	ROX N NS	Intact cells Permeabilized cells	Mouse	Fibroblast
Cesnekova 2019 Thesis	2019	Cesnekova J (2019) Functional characterization of LACE1 APTase and mitochondrial AAA proteases YME1L and AFG3L2 in mitochondrial protein homeostasis. PhD Thesis 133.	OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	HEK
Manfredini 2019 Clin Sci (Lond)	2019	Manfredini A, Constantino L, Pinto MC, Michels M, Burger H, Kist LW, Silva MC, Gomes LM, Dominguini D, Steckert A, Simioni C, Bogo M, Streck E, Barichello T, de Quevedo J, Singer M, Ritter C, Dal-Pizzol F (2019) Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model. Clin Sci (Lond) 133:1993-2004.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Nervous system
Detaille 2019 PLoS One	2019	Detaille D, Pasdois P, Sémont A, Dos Santos P, Diolez P (2019) An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals. PLoS One 14:e0216385.	LEAK OXPHOS	N S NS ROX	Isolated mitochondria	Rat	Heart
Jaiswal 2019 Mol Metab	2019	Jaiswal N, Gavin MG, Quinn WJ 3rd, Luongo TS, Gelfer RG, Baur JA, Titchenell PM (2019) The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis. Mol Metab 28:1-13.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Fang 2019 Nat Commun	2019	Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA (2019) NAD⁺ augmentation restores mitophagy and limits accelerated aging in Werner syndrome. Nat Commun 10:5284.	LEAK OXPHOS	F N S CIV ROX	Homogenate	Mouse	Heart Nervous system Liver
Zhu 2019 Aging Cell	2019	Zhu B, Li Y, Xiang L, Zhang J, Wang L, Guo B, Liang M, Chen L, Xiang L, Dong J, Liu M, Mei W, Li H, Xiang G (2019) Alogliptin improves survival and health of mice on a high-fat diet. Aging Cell 18:e12883.	LEAK OXPHOS ET	N NS S ROX	Isolated mitochondria	Mouse	Liver
Tufi 2019 Cell Rep	2019	Tufi R, Gleeson TP, von Stockum S, Hewitt VL, Lee JJ, Terriente-Felix A, Sanchez-Martinez A, Ziviani E, Whitworth AJ (2019) Comprehensive genetic characterization of mitochondriaasl Ca²⁺ uniporter components reveals their different physiological requirements in vivo. https://doi.org/10.1016/j.celrep.2019.04.033	OXPHOS	N S	Homogenate	Drosophila
Paradis 2019 Antioxidants (Basel)	2019	Paradis S, Charles AL, Georg I, Goupilleau F, Meyer A, Kindo M, Laverny G, Metzger D, Geny B (2019) Aging exacerbates ischemia-reperfusion-induced mitochondrial respiration impairment in skeletal muscle. Antioxidants (Basel) 8:E168.	LEAK OXPHOS	N S CIV	Permeabilized tissue	Mouse	Skeletal muscle
Shirakawa 2019 Sci Rep	2019	Shirakawa R, Yokota T, Nakajima T, Takada S, Yamane M, Furihata T, Maekawa S, Nambu H, Katayama T, Fukushima A, Saito A, Ishimori N, Dela F, Kinugawa S, Anzai T (2019) Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients. Sci Rep 9:14709.	LEAK OXPHOS ET	N S NS	Permeabilized cells	Human	Blood cells
Miranda Mendonca 2019 Neurochem Int	2019	Miranda Mendonça AP, Hoppe LY, Gaviraghi A, Araújo-Jorge TC, de Oliveira GM, Felippe RM, Oliveira MF, da Silva Fragoso VM (2019) Highly aggressive behavior induced by social stress is associated to reduced cytochrome c oxidase activity in mice brain cortex. Neurochem Int 126:210-17.	LEAK OXPHOS ET	N CIV ROX	Permeabilized tissue	Mouse	Nervous system
Powers 2019 Neurourol Urodyn	2019	Powers SA, Ryan TE, Pak ES, Fraser MO, McClung JM, Hannan JL (2019) Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions. Neurourol Urodyn 38:1524-32.	LEAK OXPHOS	N S CIV NS	Homogenate	Mouse	Other cell lines
Martines 2019 Sci Rep	2019	Martines AMF, Gerding A, Stolle S, Vieira-Lara MA, Wolters JC, Jurdzinski A, Bongiovanni L, de Bruin A, van der Vlies P, van der Vries G, Bloks VW, Derks TGJ, Reijngoud DJ, Bakker BM (2019) Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD⁺ in medium-chain acyl-CoA dehydrogenase knockout mice. Sci Rep 9:14539.	LEAK OXPHOS	F N	Isolated mitochondria	Mouse	Liver
Langley 2019 Biochim Biophys Acta Mol Basis Dis	2019	Langley MR, Yoon H, Kim HN, Choi CI, Simon W, Kleppe L, Lanza IR, LeBrasseur NK, Matveyenko A, Scarisbrick IA (2019) High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Acta Mol Basis Dis 1866:165630.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Nervous system
Monteiro 2019 Thesis	2019	Monteiro ARB (2019) Effects of resistance training on mitochondrial function and gene expression of UCP-3 in muscles of ovariectomized rats. Dissertation 82.	LEAK OXPHOS ET	N	Permeabilized tissue	Rat	Skeletal muscle
Fink 2019 FASEB J	2019	Fink BD, Yu L, Sivitz WI (2019) Modulation of complex II-energized respiration in muscle, heart, and brown adipose mitochondria by oxaloacetate and complex I electron flow. FASEB J 33:11696-705.	OXPHOS	N S	Isolated mitochondria	Mouse	Heart Skeletal muscle Fat
Mazzoli 2019 Nutrients	2019	Mazzoli A, Crescenzo R, Cigliano L, Spagnuolo MS, Cancelliere R, Gatto C, Iossa S (2019) Early hepatic oxidative stress and mitochondrial changes following western diet in middle aged rats. Nutrients 11:E2670.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver
Douros 2019 JCI Insight	2019	Douros JD, Niu J, Sdao SM, Gregg T, Fisher-Wellman KH, Bharadwaj MS, Molina A, Arumugam R, Martin MD, Petretto E, Merrins MJ, Herman MA, Tong J, Campbell JE, D'Alessio D (2019) Sleeve gastrectomy rapidly enhances islet function independently of body weight. JCI Insight 4:126688.	LEAK OXPHOS ET	N Gp NS	Permeabilized tissue	Mouse	Islet cell;pancreas;thymus
Halle 2019 Am J Physiol Regul Integr Comp Physiol	2019	Halle JL, Pena GS, Paez HG, Castro AJ, Rossiter HB, Visavadiya NP, Whitehurst MA, Khamoui AV (2019) Tissue-specific dysregulation of mitochondrial respiratory capacity and coupling control in colon-26 tumor-induced cachexia. Am J Physiol Regul Integr Comp Physiol 317:R68-R82.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue Intact cells	Mouse	Skeletal muscle Liver Fat
Campos 2019 Thesis	2019	Campos DF (2019) Os peixes amazônicos vivem perto dos seus limites térmicos? O efeito das mudanças climáticas sobre a ecofisiologia de peixes de Igarapé da Amazônia Central. PhD Thesis 106.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells	Fishes	Lung;gill
Dannheisig 2019 Cells	2019	Dannheisig DP, Beck E, Calzia E, Walther P, Behrends C, Pfister AS (2019) Loss of Peter Pan (PPAN) affects mitochondrial homeostasis and autophagic flux. Cells 8:E894.	LEAK ROUTINE ET	N S CIV NS ROX	Intact cells Permeabilized cells	Human	HeLa
Datzmann 2019 Pharmacol Res	2019	Datzmann T, Hoffmann A, McCook O, Merz T, Wachter U, Preuss J, Vettorazzi S, Calzia E, Gröger M, Kohn F, Schmid A, Denoix N, Radermacher P, Wepler M (2019) Effects of sodium thiosulfate (Na₂S₂O₃) during resuscitation from hemorrhagic shock in swine with preexisting atherosclerosis. Pharmacol Res 151:104536.	LEAK OXPHOS	N NS	Homogenate	Pig	Heart Liver Kidney
Weinstein 2019 bioRxiv	2019	Weinstein RN, Crawford DL (2019) Effect of EBV-transformation on oxidative phosphorylation physiology in human cell lines. bioRxiv doi: https://doi.org/10.1101/2019.12.16.878025 .	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Other cell lines Lymphocyte
Lefranc 2019 Hypertension	2019	Lefranc C, Friederich-Persson M, Braud L, Palacios-Ramirez R, Karlsson S, Boujardine N, Motterlini R, Jaisser F, Nguyen Dinh Cat A (2019) MR (mineralocorticoid receptor) induces adipose tissue senescence and mitochondrial dysfunction leading to vascular dysfunction in obesity. Hypertension 73:458-68.	OXPHOS LEAK	N	Isolated mitochondria	Mouse	Fat
Carteri 2019 Toxicol Lett	2019	Carteri RB, Kopzynski A, Menegassi LN, Rodolphi MS, Strogulski NR, Portela LV (2019) Anabolic-androgen steroids effects on bioenergetics responsiveness of synaptic and extrasynaptic mitochondria. Toxicol Lett 307:72-80.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Nervous system
Fiorenza 2019 FASEB J	2019	Fiorenza M, Lemminger AK, Marker M, Eibye K, Iaia FM, Bangsbo J, Hostrup M (2019) High-intensity exercise training enhances mitochondrial oxidative phosphorylation efficiency in a temperature-dependent manner in human skeletal muscle: implications for exercise performance. FASEB J 33:8976-89.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Chabi 2019 MitoFit Preprint Arch EA	2019	Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. https://doi.org/10.26124/mitofit:ea19.MitoEAGLE.0001	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Nunes 2019 Oxid Med Cell Longev	2019	Nunes MEM, Schimith LE, da Costa-Silva DG, Lopes AR, Leandro LP, Martins IK, de Mello RS, Hartmann DD, de Carvalho NR, Carvalho da Rosa P, Trevisan R, Di Giulio RT, Posser T, Franco JL (2019) Acute exposure to permethrin modulates behavioral functions, redox, and bioenergetics parameters and induces DNA damage and cell death in larval zebrafish. Oxid Med Cell Longev 2019:9149203.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Homogenate	Zebrafish
Hughes 2019 J Physiol	2019	Hughes MC, Ramos SV, Turnbull PC, Edgett BA, Huber JS, Polidovitch N, Schlattner U, Backx PH, Simpson JA, Perry CGR (2019) Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy. J Physiol 598:1377-92.	OXPHOS LEAK	N NS	Permeabilized tissue	Mouse	Heart
Petrick 2019 J Physiol	2019	Petrick HL, Pignanelli C, Barbeau PA, Churchward-Venne TA, Dennis KMJH, van Loon LJC, Burr JF, Goossens GH, Holloway GP (2019) Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H₂O₂ emission rates in human skeletal muscle. J Physiol 597:3985-97.	LEAK OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Ederle 2019 J Clin Med	2019	Ederle C, Charles AL, Khayath N, Poirot A, Meyer A, Clere-Jehl R, Andres E, De Blay F, Geny B (2019) Mitochondrial function in peripheral blood mononuclear cells (PBMC) is enhanced, together with increased reactive oxygen species, in severe asthmatic patients in exacerbation. J Clin Med 8:E1613.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Blood cells
Kwak 2019 Int J Environ Res Public Health	2019	Kwak HB, Woodlief TL, Green TD, Cox JH, Hickner RC, Neufer PD, Cortright RN (2019) Overexpression of long-chain acyl-CoA synthetase 5 increases fatty acid oxidation and free radical formation while attenuating insulin signaling in primary human skeletal myotubes. Int J Environ Res Public Health 16:E1157.	LEAK OXPHOS ET	F N NS	Permeabilized cells	Human	Skeletal muscle
Azevedo 2019 Food Chem Toxicol	2019	Azevedo LF, Porto Dechandt CR, Cristina de Souza Rocha C, Hornos Carneiro MF, Alberici LC, Barbosa F Jr (2019) Long-term exposure to bisphenol A or S promotes glucose intolerance and changes hepatic mitochondrial metabolism in male Wistar rats. Food Chem Toxicol 132:110694.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Rat	Liver
Cannon 2019 J Appl Physiol (1985)	2019	Cannon DT, Rodewohl L, Adams V, Breen EC, Bowen TS (2019) Skeletal myofiber VEGF deficiency leads to mitochondrial, structural and contractile alterations in mouse diaphragm. J Appl Physiol (1985) 127:1360-69.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Zhao 2019 Basic Res Cardiol	2019	Zhao J, Gao JL, Zhu JX, Zhu HB, Peng X, Jiang M, Fu Y, Xu J, Mao XH, Hu N, Ma MH, Dong DL (2019) The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3. Basic Res Cardiol 114:12.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Rat	Heart Fibroblast
Calabria 2019 Front Neurosci	2019	Calabria Elisa, Scambi Ilaria, Bonafede Roberta, Schiaffino Lorenzo, Peroni Daniele, Potrich Valentina, Capelli Carlo, Schena Federico, Mariotti Raffaella (2019) ASCs-exosomes recover coupling efficiency and mitochondrial membrane potential in an in vitro model of ALS. Front Neurosci 13:1070.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Mouse	Nervous system
Pedrotti 2019 Sci Adv	2019	Pedrotti S, Caccia R, Neguembor MV, Garcia-Manteiga JM, Ferri G, de Palma C, Canu T, Giovarelli M, Marra P, Fiocchi A, Molineris I, Raso M, Sanvito F, Doglioni C, Esposito A, Clementi E, Gabellini D (2019) The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli. Sci Adv 5:eaav1472.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells	Mouse	Fat
Wang 2019 Life Sci	2019	Wang JW, Xue ZY, Wu AS (2019) Mechanistic insights into δ-opioid-induced cardioprotection: Involvement of caveolin translocation to the mitochondria. Life Sci 247:116942.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Heart
Ahmed 2019 Mol Nutr Food Res	2019	Ahmed N, Tcheng M, Roma A, Buraczynski M, Jayanth P, Rea K, Akhtar TA, Spagnuolo PA (2019) Avocatin B protects against lipotoxicity and improves insulin sensitivity in diet-induced obesity. Mol Nutr Food Res 63:e1900688.	LEAK ROUTINE ET	N ROX	Intact cells	Mouse Rat	Skeletal muscle Islet cell;pancreas;thymus
Robinson 2019 Am J Physiol Cell Physiol	2019	Robinson MM, Sather BK, Burney ER, Ehrlicher SE, Stierwalt HD, Franco MC, Newsom SA (2019) Robust intrinsic differences in mitochondrial respiration and H₂O₂ emission between L6 and C2C12 cells. Am J Physiol Cell Physiol 317:C339-C347.	LEAK OXPHOS ET	F N S Gp NS Other combinations ROX	Permeabilized cells	Mouse Rat	Skeletal muscle
Esteves 2019 Oncogene	2019	Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, Dumon E, Izotte J, Bonneu M, Lacombe D, Dupuy JW, Amoedo N, Rossignol R (2019) Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F. Oncogene 39:617-36.	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell
Glombik 2019 Neurotox Res	2019	Głombik K, Detka J, Góralska J, Kurek A, Solnica B, Budziszewska B (2019) Brain metabolic alterations in rats showing depression-like and obesity phenotypes. Neurotox Res 37:406-24.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Paumelle 2019 J Hepatol	2019	Paumelle R, Haas J, Hennuyer N, Bauge E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B (2019) Hepatic PPARα is critical in the metabolic adaptation to sepsis. J Hepatol 70:963-73.	OXPHOS LEAK	F N	Homogenate	Human	Liver
Ferey 2019 Am J Physiol Heart Circ Physiol	2019	Ferey J, Boudoures AL, Reid M, Drury A, Scheaffer S, Modi Z, Kovacs A, Pietka T, DeBosch BJ, Thompson MD, Diwan A, Moley KH (2019) Maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independent of maternal mitochondrial inheritance. Am J Physiol Heart Circ Physiol 316:H1202-H1210.	LEAK OXPHOS	N S NS	Permeabilized tissue	Mouse	Heart
Zhou 2019 Int J Mol Sci	2019	Zhou X, Luethi D, Sanvee GM, Bouitbir J, Liechti ME, Krähenbühl S (2019) Molecular toxicological mechanisms of synthetic cathinones on C2C12 myoblasts. Int J Mol Sci 20:E1561.	OXPHOS	N	Permeabilized cells	Mouse	Skeletal muscle
Teulier 2019 Comp Biochem Physiol A Mol Integr Physiol	2019	Teulier L, Thoral E, Queiros Q, McKenzie DJ, Roussel D, Dutto G, Gasset E, Bourjea J, Saraux C (2019) Muscle bioenergetics of two emblematic Mediterranean fish species: Sardina pilchardus and Sparus aurata. Comp Biochem Physiol A Mol Integr Physiol 235:174-79.	LEAK OXPHOS ET	F N NS ROX	Intact cells	Fishes	Skeletal muscle
Kim 2019 Biochim Biophys Acta Mol Basis Dis	2019	Kim HK, Jeon J, Song IS, Heo HJ, Jeong SH, Long LT, Thu VT, Ko TH, Kim M, Kim N, Lee SR, Yang JS, Kang MS, Ahn JM, Cho JY, Ko KS, Rhee BD, Nilius B, Ha NC, Shimizu I, Minamino T, Cho KI, Park YS, Kim S, Han J (2019) Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling. Biochim Biophys Acta Mol Basis Dis 1865:165524.	LEAK OXPHOS	N	Isolated mitochondria Permeabilized tissue	Mouse	Heart
Bodis 2019 J Clin Endocrinol Metab	2019	Bodis K, Jelenik T, Lundbom J, Markgraf DF, Strom A, Zaharia OP, Karusheva Y, Burkart V, Muessig K, Kupriyanova Y, Ouni M, Wolkersdorfer M, Hwang JH, Ziegler D, Schuermann A, Roden M, Szendroedi J (2019) Expansion and impaired mitochondrial efficiency of deep subcutaneous adipose tissue in recent-onset type 2 diabetes. J Clin Endocrinol Metab 105:dgz267.	LEAK OXPHOS ET	F N NS	Permeabilized cells	Human	Fat
Friederich 2019 Mol Genet Metab	2019	Friederich MW, Perez FA, Knight KM, Van Hove RA, Yang SP, Saneto RP, Van Hove JLK (2019) Pathogenic variants in NUBPL result in failure to assemble the matrix arm of complex I and cause a complex leukoencephalopathy with thalamic involvement. Mol Genet Metab 129:236-42.	OXPHOS ET	N S CIV NS		Human	Fibroblast
Ahn 2019 J Cachexia Sarcopenia Muscle	2019	Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, Griffin TM, Freeman WM, Richardson A, Brooks SV, Van Remmen H (2019) Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fiber branching. J Cachexia Sarcopenia Muscle 10:411-28.	OXPHOS LEAK	N S CIV NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Koop 2019 Int J Cardiol	2019	Koop AMC, Hagdorn QAJ, Bossers GPL, van Leusden T, Gerding A, van Weeghel M, Vaz FM, Koonen DPY, Silljé HHW, Berger RMF, Bartelds B (2019) Right ventricular pressure overload alters cardiac lipid composition. Int J Cardiol 287:96-105.	OXPHOS	F N	Isolated mitochondria	Rat	Heart
Majiene 2019 Nutrients	2019	Majiene D, Kuseliauskyte J, Stimbirys A, Jekabsone A (2019) Comparison of the effect of native 1,4-naphthoquinones plumbagin, menadione, and lawsone on viability, redox status, and mitochondrial functions of C6 glioblastoma cells. Nutrients 11:E1294.	LEAK OXPHOS ET	N NS	Permeabilized cells	Rat	Nervous system
Latham 2019 J Anim Sci	2019	Latham CM, Fenger CK, White SH (2019) Rapid Communication: Differential skeletal muscle mitochondrial characteristics of weanling racing-bred horses. J Anim Sci [Epub ahead of print].	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Holsgrove 2019 Thesis	2019	Holsgrove A (2019) The effect of temperature on cardiac energetics in the rainbow trout, Onchorhynchus mykiss. Phd Thesis 166.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Fishes	Heart
Stepanova 2019 Antioxid Redox Signal	2019	Stepanova Anna, Sosunov S, Niatsetskaya Z, Konrad Csaba, Starkov AA, Manfredi G, Wittig I, Ten V, Galkin A (2019) Redox-dependent loss of flavin by mitochondrial complex I in brain ischemia/reperfusion injury. Antioxid Redox Signal 31:608-22.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Nervous system
Papadimitriou 2019 Sci Rep	2019	Papadimitriou ID, Eynon N, Yan X, Munson F, Jacques M, Kuang J, Voisin S, North KN, Bishop DJ (2019) A "human knockout" model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations. Sci Rep 9:12688.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Wang 2019 Metabolism	2019	Wang D, Liu CD, Li HF, Tian ML, Pan JQ, Shu G, Jiang QY, Yin YL, Zhang L (2019) LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue. Metabolism 102:154011.	LEAK	F N	Isolated mitochondria	Mouse	Fat
Mann 2019 Oncogene	2019	Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (2019) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene 38:3325-39.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX F	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell
Rodriguez-Enriquez 2019 Toxicol Appl Pharmacol	2019	Rodríguez-Enríquez S, Pacheco-Velázquez SC, Marín-Hernández Á, Gallardo-Pérez JC, Robledo-Cadena DX, Hernández-Reséndiz I, García-García JD, Belmont-Díaz J, López-Marure R, Hernández-Esquivel L, Sánchez-Thomas R, Moreno-Sánchez R (2019) Resveratrol inhibits cancer cell proliferation by impairing oxidative phosphorylation and inducing oxidative stress. Toxicol Appl Pharmacol 370:65-77.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Heart Liver
Desquiret-Dumas 2019 Biochim Biophys Acta Mol Basis Dis	2019	Desquiret-Dumas V, Leman G, Wetterwald C, Chupin S, Lebert A, Khiati S, Le Mao M, Geffroy G, Kane MS, Chevrollier A, Goudenege D, Gadras C, Tessier L, Barth M, Leruez S, Amati-Bonneau P, Henrion D, Bonneau D, Procaccio V, Reynier P, Lenaers G, Gueguen N (2019) Warburg-like effect is a hallmark of complex I assembly defects. Biochim Biophys Acta Mol Basis Dis 1865:2475-89.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Hunter 2019 J Appl Physiol (1985)	2019	Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between VO_2max, cycle economy & mitochondrial respiration in untrained/trained. J Appl Physiol (1985) 127:1562-68.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Chang 2019 Br J Anaesth	2019	Chang L, Daly C, Miller DM, Allen PD, Boyle JP, Hopkins PM, Shaw MA (2019) Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals. Br J Anaesth 122:613-21.	LEAK OXPHOS ET	N S CIV NS ROX		Human	Skeletal muscle
Doerrier 2019 MitoFit Preprint Arch EA	2019	Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Trevino 2019 Am J Physiol Endocrinol Metab	2019	Trevino MB, Zhang X, Standley RA, Wang M, Han X, Reis FCG, Periasamy M1, Yu G, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2019) Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy. Am J Physiol Endocrinol Metab 317:E899-910.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Shrum 2019 Biomolecules	2019	Shrum S, Rusch NJ, MacMillan-Crow LA (2019) Specific BK channel activator NS11021 protects rat renal proximal tubular cells from cold storage-induced mitochondrial injury in vitro. Biomolecules 9:E825.	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Rat	Kidney
Fisher-Wellman 2019 Cell Rep	2019	Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM (2019) Respiratory phenomics across multiple models of protein hyperacylation in cardiac mitochondria reveals a marginal impact on bioenergetics. Cell Rep 26:1557-72.	LEAK OXPHOS ET	F N S Gp	Isolated mitochondria	Mouse	Heart Skeletal muscle
Power 2019 PLoS One	2019	Power AS, Norman R, Jones TLM, Hickey AJ, Ward ML (2019) Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment. PLoS One 14:e0214740.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Heart
Tarpey 2019 J Biol Chem	2019	Tarpey MD, Amorese AJ, Balestrieri NP, Fisher-Wellman KH, Spangenburg EE (2019) Doxorubicin causes lesions in the electron transport system of skeletal muscle mitochondria that are associated with a loss of contractile function. J Biol Chem 294:19709-22.	LEAK ET	F N S CIV	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Chiba 2019 J Am Soc Nephrol	2019	Chiba T, Peasley KD, Cargill KR, Maringer KV, Bharathi SS, Mukherjee E, Zhang Y, Holtz A, Basisty N, Yagobian SD, Schilling B, Goetzman ES, Sims-Lucas S (2019) Sirtuin 5 regulates proximal tubule fatty acid oxidation to protect against AKI. J Am Soc Nephrol 30:2384-98.	OXPHOS	N S	Homogenate	Mouse	Kidney
Hafen 2019 J Appl Physiol (1985)	2019	Hafen PS, Abbott K, Bowden JA, Lopiano R, Hancock CR, Hyldahl RD (2019) Daily heat treatment maintains mitochondrial function and attenuates atrophy in human skeletal muscle subjected to immobilization. J Appl Physiol (1985) 127:47-57. https://doi.org/10.1152/japplphysiol.01098.2018	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Pignanelli 2019 Thesis	2019	Pignanelli CJ (2019) Muscular adaptations to low-load resistance training to repetition failure with and without blood flow restriction. Master's Thesis 80.	LEAK OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Grauso 2019 Sci Rep	2019	Grauso M, Lan A, Andriamihaja M, Bouillaud F, Blachier F (2019) Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro. Sci Rep 9:11360.	LEAK ROUTINE OXPHOS ET	N NS	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Wiberg 2019 Eur Heart J Acute Cardiovasc Care	2019	Wiberg S, Stride N, Bro-Jeppesen J, Holmberg MJ, Kjærgaard J, Larsen S, Donnino MW, Hassager C, Dela F (2019) Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest. Eur Heart J Acute Cardiovasc Care 9:S138-44.	OXPHOS ET LEAK	N NS	Permeabilized tissue	Human	Skeletal muscle
Chroeis 2019 Eur J Sport Sci	2019	Chrøis KM, Dohlmann TL, Søgaard D, Hansen CV, Dela F, Helge JW, Larsen S (2019) Mitochondrial adaptations to high intensity interval training in older females and males. Eur J Sport Sci 20:135-45.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Cooper 2019 Exp Physiol	2019	Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2019) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12.	LEAK OXPHOS ET	F N	Permeabilized tissue	Mouse	Nervous system
Poudel 2019 Can J Physiol Pharmacol	2019	Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L (2019) Berberine hydrochloride protects against cytokine-induced inflammation through multiple pathways in undifferentiated C2C12 myoblast cells. Can J Physiol Pharmacol 97:699-707.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Mouse	Skeletal muscle
Kappler 2019 Am J Physiol Endocrinol Metab	2019	Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, Häring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R (2019) Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints. Am J Physiol Endocrinol Metab 317:E374-E387.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue Isolated mitochondria	Human Mouse	Skeletal muscle Liver
Gvozdjakova 2019 Bratisl Lek Listy	2019	Gvozdjakova A, Sumbalova Z, Kucharska J, Chladekova A, Rausova Z, Vancova O, Komlosi M, Ulicna O, Mojto V (2019) Platelet mitochondrial bioenergetic analysis in patients with nephropathies and non-communicable diseases: a new method. Bratisl Lek Listy 120:630-35.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human	Platelet Blood cells
Svensson 2019 Am J Physiol Endocrinol Metab	2019	Svensson K, Tahvilian S, Martins VF, Dent JR, Lemanek A, Barooni N, Greyslak K, McCurdy CE, Schenk S (2019) Combined overexpression of SIRT1 and knockout of GCN5 in adult skeletal muscle does not affect glucose homeostasis or exercise performance in mice. Am J Physiol Endocrinol Metab 318:E145-51.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Courtes 2019 Biomed Pharmacother	2019	Courtes AA, de Carvalho NR, Gonçalves DF, Hartmann DD, da Rosa PC, Dobrachinski F, Franco JL, de Souza DOG, Soares FAA (2019) Guanosine protects against Ca²⁺-induced mitochondrial dysfunction in rats. Biomed Pharmacother 111:1438-46.	OXPHOS LEAK	N S NS ROX	Isolated mitochondria	Rat	Liver
Sukovas 2019 J Bioenerg Biomembr	2019	Sukovas A, Silkuniene G, Trumbeckaite S, Jasukaitiene A, Degutyte-Fomins L, Mildaziene V, Gulbinas A, Baniene R, Dambrauskas Z, Paskauskas S (2019) Hyperthermia potentiates cisplatin cytotoxicity and negative effects on mitochondrial functions in OVCAR-3 cells. J Bioenerg Biomembr 51:301-10.	LEAK OXPHOS	N	Permeabilized cells	Human	Genital
Mejia 2019 Reprod Biol Endocrinol	2019	Mejia JF, Hirschi KM, Tsai KYF, Long MG, Tullis BC, Bitter EEK, Bikman BT, Reynolds PR, Arroyo JA (2019) Differential placental ceramide levels during gestational diabetes mellitus (GDM). Reprod Biol Endocrinol 17:81.	LEAK OXPHOS ET	N NS	Permeabilized cells	Human	Genital
Zhang 2019 Nephron	2019	Zhang R, Wang X, Gao Q, Jiang H, Zhang S, Lu M, Liu F, Xue X (2019) Taurine supplementation reverses diabetes-induced podocytes injury via modulation of the CSE/TRPC6 axis and improvement of mitochondrial function. Nephron 144:84-95.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells	Mouse	Kidney
Scheiber 2019 Exp Mol Med	2019	Scheiber D, Jelenik T, Zweck E, Horn P, Schultheiss HP, Lassner D, Boeken U, Saeed D, Kelm M, Roden M, Westenfeld R, Szendroedi J (2019) High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure. Exp Mol Med 51:16.	LEAK OXPHOS ET	F N NS	Permeabilized tissue Isolated mitochondria	Human	Heart
Anton 2019 Front Physiol	2019	Anton L, DeVine A, Polyak E, Olarerin-George A, Brown AG, Falk MJ, Elovitz MA (2019) HIF-1α stabilization increases miR-210 eliciting first trimester extravillous trophoblast mitochondrial dysfunction. Front Physiol 10:699.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Genital
Bettinazzi 2019 Cryobiology	2019	Bettinazzi S, Gendron AD, Breton S (2019) The effect of cryopreservation on mitochondrial function in freshwater mussel tissue samples (Bivalvia: Unionida). Cryobiology 88:106-109.	LEAK OXPHOS ET	N Gp CIV NS ROX S Other combinations	Permeabilized tissue	Molluscs	Lung;gill
Dechandt 2019 Front Neurol	2019	Dechandt CRP, Ferrari GD, Dos Santos JR, de Oliveira JAC, da Silva-Jr RMP, Cunha AOS, Garcia-Cairasco N, Alberici LC (2019) Energy metabolism and redox state in brains of wistar audiogenic rats, a genetic model of epilepsy. Front Neurol 10:1007.	LEAK OXPHOS ET	N ROX	Permeabilized tissue	Rat	Nervous system
Flis 2019 Int J Mol Sci	2019	Flis DJ, Dzik K, Kaczor JJ, Cieminski K, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2019) Swim training modulates mouse skeletal muscle energy metabolism and ameliorates reduction in grip strength in a mouse model of amyotrophic lateral sclerosis. Int J Mol Sci 20:E233.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Thomas 2019 Redox Biol	2019	Thomas NO, Shay KP, Hagen TM (2019) Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I. Redox Biol 22:101155.	LEAK OXPHOS ET	N S NS ROX	Intact cells	Rat	Liver
Cedrone 2019 Thesis	2019	Cedrone M (2019) Low birth weight and post-natal diet induced alterations in skeletal muscle oxygen consumption and fiber type composition. Master's Thesis 83.	LEAK OXPHOS	N S	Permeabilized tissue Intact cells	Guinea pig Mouse	Skeletal muscle
Lemieux 2019 bioRxiv	2019	Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 .	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Blood cells
Axton 2019 J Nutr	2019	Axton ER, Beaver LM, St Mary L, Truong L, Logan CR, Spagnoli S, Prater MC, Keller RM, Garcia-Jaramillo M, Ehrlicher SE, Stierwalt HD, Newsom SA, Robinson MM, Tanguay RL, Stevens JF, Hord NG (2019) Treatment with nitrate, but not nitrite, lowers the oxygen cost of exercise and decreases glycolytic intermediates while increasing fatty acid metabolites in exercised zebrafish. J Nutr 00:1–13.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Zebrafish	Skeletal muscle

Semantic search

Query log