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From Bioblast
 YearReferenceMammal and modelTissue and cellStressDiseases
Distefano 2016 J Gerontol A Biol Sci Med Sci2016Distefano G, Standley RA, Dubé JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42.HumanSkeletal muscleAging;senescence
Iglesias-Gonzalez 2016 Mol Neurobiol2016Iglesias-Gonzålez J, Sånchez-Iglesias S, Beiras-Iglesias A, Méndez-Álvarez E, Soto-Otero R (2016) Effects of aluminium on rat brain mitochondria bioenergetics: an in vitro and in vivo study. Mol Neurobiol 54:563-70.RatNervous systemAlzheimer's
Neurodegenerative
Parkinson's
Leucci 2016 Nature2016Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22.HumanEndothelial;epithelial;mesothelial cell
Other cell lines		Cancer
Lores-Arnaiz 2016 Neurochem Res2016Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63.MouseNervous systemAging;senescence
Shama 2016 Evol Appl2016Shama LNS, Mark FC, Strobel A, Lokmer A, John U, Wegner KM (2016) Transgenerational effects persist down the maternal line in marine sticklebacks: gene expression matches physiology in a warming ocean. Evol Appl 10013/epic.47323.FishesHeartTemperature
Khattar 2016 J Neurosci Methods2016Khattar NK, Yablonska S, Baranov SV, Baranova OV, Kretz ES, Larkin TM, Carlisle DL, Richardson RM, Friedlander RM (2016) Isolation of functionally active and highly purified neuronal mitochondria from human cortex. J Neurosci Methods 263:1-6.Human
Mouse		Nervous system
Price 2016 J Thermal Biol2016Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11.ReptilesHeart
Skeletal muscle		Temperature
Roy 2016 Free Radic Biol Med2016Roy J, Fauconnier J, Oger C, Farah C, Angebault-Prouteau C, Thireau J, Bideaux P, Scheuermann V, Bultel-Poncé V, Demion M, Galano JM, Durand T, Lee JC, Le Guennec JY (2016) Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury. Free Radic Biol Med 102:229-39.RatHeartIschemia-reperfusion
Permeability transition
Oxidative stress;RONS		Cardiovascular
Gemmink 2016 Diabetologia2016Gemmink A, Bosma M, Kuijpers HJ, Hoeks J, Schaart G, van Zandvoort MA, Schrauwen P, Hesselink MK (2016) Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia 59:1040-8.HumanSkeletal muscleDiabetes
Yavari 2016 Cell Metab2016Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of Îł2 AMPK induces obesity and reduces ÎČ cell function. Cell Metab 23:821-36.MouseNervous systemAging;senescence
Obesity
Dechandt 2016 Anal Biochem2016Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60.RatFat
Witt 2016 Metab Brain Dis2016Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70.RatNervous systemOther
Amaral 2016 J Neurochem2016Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.RatNervous systemPermeability transitionNeurodegenerative
Seiferling 2016 EMBO Rep2016Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, König T, Kukat A, Trifunovic A (2016) Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep 17:953-64.MouseHeartCardiovascular
Keller 2016 Oxid Med Cell Longev2016Keller AC, Knaub LA, McClatchey PM, Connon CA, Bouchard R, Miller MW, Geary KE, Walker LA, Klemm DJ, Reusch JE (2016) Differential mitochondrial adaptation in primary vascular smooth muscle cells from a diabetic rat model. Oxid Med Cell Longev 2016:8524267.RatEndothelial;epithelial;mesothelial cellOxidative stress;RONSDiabetes
McCurdy 2016 JCI Insight2016McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE (2016) Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight 1:e86612.Other mammalsSkeletal muscleInherited
Obesity
Other
Asseburg 2016 Neuromolecular Med2016Asseburg H, SchĂ€fer C, MĂŒller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95.MouseNervous systemAging;senescence
Chu 2016 World J Gastroenterol2016Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84.RatLiverIschemia-reperfusionObesity
Other
Volt 2016 J Pineal Res2016Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.MouseHeartAging;senescence
Sepsis
Moore 2016 Cryobiology2016Moore DS, Hand SC (2016) Cryopreservation of lipid bilayers by LEA proteins from Artemia franciscana and trehalose. Cryobiology 73:240-7.RatLiverCryopreservation
Santos 2016 Insect Biochem Mol Biol2016Santos DE, Alberici LC, Hartfelder K (2016) Mitochondrial structure and dynamics as critical factors in honey bee (Apis mellifera L.) caste development. Insect Biochem Mol Biol 73:1-11.HexapodsFatOxidative stress;RONS
LaBarge 2016 FASEB J2016LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33.MouseSkeletal muscle
Timmers 2016 Diabetes Care2016Timmers S, de Ligt M, Phielix E, van de Weijer T, Hansen J, Moonen-Kornips E, Schaart G, Kunz I, Hesselink MK, Schrauwen-Hinderling VB, Schrauwen P (2016) Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial. Diabetes Care 39:2211-17.HumanSkeletal muscleDiabetes
Tyrrell 2016 Redox Biol2016Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77. https://doi.org/10.1016/j.redox.2016.09.009Other mammals
Human		Skeletal muscle
Blood cells
Platelet
Du 2016 Aquat Toxicol2016Du X, Crawford DL, Nacci DE, Oleksiak MF (2016) Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol 177:44-50.FishesLiver
Vevera 2016 Physiol Res2016Vevera J, Fiơar Z, Nekováƙová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeơ K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88.Human
Rat		Blood cells
Platelet
Wijermars 2016 Am J Transplant2016Wijermars LG, Schaapherder AF, Kostidis S, WĂŒst RC, Lindeman JH (2016) Succinate accumulation and ischemia reperfusion injury: of mice but not men - A study in renal ischemia reperfusion. Am J Transplant 16:2741-6.Human
Pig
Mouse
Rat		KidneyIschemia-reperfusion
Oxidative stress;RONS
Nissinen 2016 Sci Rep2016Nissinen TA, Degerman J, RÀsÀnen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, KivelÀ R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695.MouseSkeletal muscleCancer
Brecht 2016 Toxicol In Vitro2016Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, KrĂ€henbĂŒhl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.HumanIslet cell;pancreas;thymusCancer
Ryan 2016 Diabetes2016Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68.MouseSkeletal muscleIschemia-reperfusionDiabetes
Gomez 2016 Thesis2016Gomez CR (2016) Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). Master's Thesis p102.ReptilesHeart
Nervous system		Oxidative stress;RONS
Grimm 2016 Methods Mol Biol2016Grimm A, Schmitt K, Eckert A (2016) Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83.MouseNervous systemAlzheimer's
Torres 2016 Redox Biol2016Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernåndez-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72.Human
Mouse		Nervous system
Liver
Endothelial;epithelial;mesothelial cell
Fibroblast		Other
Chang 2016 Transl Res2016Chang JC, Wu SL, Liu KH, Chen YH, Chuang CS, Cheng FC, Su HL, Wei YH, Kuo SJ, Liu CS (2016) Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity. Transl Res 170:40-56.RatNervous system
Other cell lines		Parkinson's
Van Zutphen 2016 J Hepatol2016van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208.RatLiver
Bonifacio 2016 Arch Toxicol2016Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, KrĂ€henbĂŒhl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4RatHeart
Bai 2016 PLOS ONE2016Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982.MouseHeart
Skeletal muscle
Nervous system
Liver		Oxidative stress;RONS
Queliconi 2016 PLOS ONE2016Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678.RatHeartIschemia-reperfusion
Ehinger 2016 Mov Disord2016Ehinger JK, Morota S, Hansson MJ, Gesine P, ElmĂ©r E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308.HumanBlood cells
Lymphocyte
Platelet		Neurodegenerative
Mizushima 2016 J Mol Cell Cardiol2016Mizushima W, Takahashi H, Watanabe M, Kinugawa S, Matsushima S, Takada S, Yokota T, Furihata T, Matsumoto J, Tsuda M, Chiba I, Nagashima S, Yanagi S, Matsumoto M, Nakayama KI, Tsutsui H, Hatakeyama S (2016) The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes. J Mol Cell Cardiol 100:43-53.RatHeartCardiovascular
Lemieux 2016 Mitochondrion2016Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41.HorseSkeletal muscleMyopathy
Gregg 2016 Diabetes2016Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic ÎČ cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity. Diabetes 65:2700-10.Human
Mouse		Islet cell;pancreas;thymus
Other cell lines		Aging;senescence
Ferguson 2016 J Bioenerg Biomembr2016Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79.PigNervous system
Platelet		Cardiovascular
McFarlane 2016 Thesis2016McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74.Other mammalsFatTemperature
Most 2016 Am J Clin Nutr2016Most J, Timmers S, Warnke I, Jocken JW, van Boekschoten M, de Groot P, Bendik I, Schrauwen P, Goossens GH, Blaak EE (2016) Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. Am J Clin Nutr 104:215-27.HumanSkeletal muscleDiabetes
Obesity
Fisar 2016b Folia Biol (Praha)2016Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66.PigNervous system
Du 2016 J Exp Biol2016Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.FishesLiverOxidative stress;RONS
Soendergaard 2016 Eur J Sport Sci2016SÞndergÄrd SD, Dela F, Helge JW, Larsen S (2016) Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci 16:801-7.HumanSkeletal muscle
Fisar 2016a Folia Biol (Praha)2016Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25.PigNervous system
Briston 2016 Sci Rep2016Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.RatLiverCryopreservation
Permeability transition
Ryan 2016 J Mol Cell Cardiol2016Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6.MouseSkeletal muscleIschemia-reperfusion
Camacho-Pereira 2016 Cell Metab2016Camacho-Pereira J, TarragĂł MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39.Human
Mouse		Liver
Lung;gill
Other cell lines		Aging;senescence
Lund 2016 J Physiol2016Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, StĂžckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8.HumanLiverDiabetes
Obesity
Mills 2016 Cell Metab2016Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12.MouseSkeletal muscleAging;senescence
Rackham 2016 Cell Rep2016Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A (2016) Hierarchical RNA processing is required for mitochondrial ribosome assembly. Cell Rep 16:1874-90.MouseHeart
Smith 2016 Diabetes2016Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK ÎČ1. Diabetes 65:3352-61.MouseSkeletal muscle
Liver
Fat		Diabetes
Ehinger 2016 Nat Commun2016Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, ElmĂ©r E (2016) Cell-permeable succinate prodrugs bypass mitochondrial Complex I deficiency. Nat Commun 7:12317. https://doi.org/10.1038/ncomms12317Heart
Blood cells
Fibroblast		Mitochondrial diseaseInherited
Zabielski 2016 Diabetes2016Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73.MouseSkeletal muscleOxidative stress;RONSDiabetes
Pamenter 2016 Biol Lett2016Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797.ReptilesNervous systemOxidative stress;RONS
MiPNet17.03 Shredder vs Fibers2015-06-18
O2k-Protocols

Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder.

FishesHeart
Liver
Peyta 2015 Biochim Biophys Acta2015Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2015) Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia. Biochim Biophys Acta 1851:1490-500.RatLiver
Other cell lines		Cancer
Senyilmaz 2015 Nature2015Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8.DrosophilaParkinson's
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.MouseHeart
Liver		Oxidative stress;RONSSepsis
Porter 2015 Med Sci Sports Exerc2015Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31.HumanSkeletal muscle
Clemens 2015 Brain2015Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53.RatNervous systemNeurodegenerative
Duicu 2015 Biomed Res Int2015Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437.HumanHeartOxidative stress;RONSCardiovascular
Diabetes
Konopka 2015 Diabetes2015Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15.HumanSkeletal muscleOxidative stress;RONSDiabetes
Obesity
Schwarzkopf 2015 Neuroscience2015Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9.MouseNervous systemIschemia-reperfusionCardiovascular
Hagl 2015 Neurochem Int2015Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42.MouseNervous system
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol2015PlecitĂĄ-HlavatĂĄ L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, JeĆŸek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57.Human
Bovines		Endothelial;epithelial;mesothelial cell
Fibroblast		Oxidative stress;RONSOther
Kluckova 2015 Cell Death Dis2015Kluckova K, Sticha M, Cerny J, Mracek T, Dong L, Drahota Z, Gottlieb E, Neuzil J, Rohlena J (2015) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749.Other mammalsLung;gill
Other cell lines
Fibroblast		Cell death
Oxidative stress;RONS
Montero 2015 J Physiol2015Montero D, Cathomen A, Jacobs RA, FlĂŒck D, de Leur J, Keiser S, Bonne T, Kirk N, Lundby AK, Lundby C (2015) Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. J Physiol 593:4677-88.HumanSkeletal muscle
Grabez 2015 J Anim Sci2015GrabeĆŸ V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79.BovinesSkeletal muscle
Pasdar 2015 PLoS One2015Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549.Human
Mouse		Endothelial;epithelial;mesothelial cell
Other cell lines		Cancer
Jiroutkova 2015 Crit Care2015JiroutkovĂĄ K, KrajčovĂĄ A, Ziak J, Fric M, Waldauf P, DĆŸupa V, Gojda J, Němcova-FĂŒrstovĂĄ V, Kováƙ J, Elkalaf M, Trnka J, DuĆĄka F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448.HumanSkeletal muscleOther
Maiti 2015 PhD Thesis2015Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120.MouseHeart
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol2015Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9.RatLiverDiabetes
Obesity
Kilbaugh 2015 J Am Heart Assoc2015Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232.PigNervous systemIschemia-reperfusionCardiovascular
Baris 2015 Am J Physiol Regul Integr Comp Physiol2015Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96.FishesHeartTemperature
Crombie 2015 Biochem Biophys Rep2015Crombie DE, van Bergena N, Davidsona KC, Anjomani Virmounib S, Mckelviec PA, Chrysostomoua V, Conquesta A, Corbend LA, Pookb MA, Kulkarnia T, Trouncea IA, Peraf MF, Delatyckid MB, PĂ©baya A (2015) Characterization of the retinal pigment epithelium in Friedreich ataxia. Biochem Biophys Rep 4:141–7.HumanNervous system
Endothelial;epithelial;mesothelial cell
Stem cells		Neurodegenerative
Bratic 2015 Nat Commun2015Bratic A, Kauppila TE, Macao B, Grönke S, Siibak T, Stewart JB, Baggio F, Dols J, Partridge L, Falkenberg M, Wredenberg A, Larsson NG (2015) Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies. Nat Commun 6:8808.Drosophila
Hexapods
Sjoevall 2015 US Patent2015Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1.HumanBlood cells
Macrophage-derived
Platelet
Hals 2015 PLoS One2015Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing ÎČ-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558.RatIslet cell;pancreas;thymus
Other cell lines		Oxidative stress;RONS
Coen 2015 Diabetes2015Coen PM, Menshikova EV, Distefano G, Zheng D, Tanner CJ, Standley RA, Helbling NL, Dubis GS, Ritov VB, Xie H, Desimone ME, Smith SR, Stefanovic-Racic M, Toledo FG, Houmard JA, Goodpaster BH (2015) Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery. Diabetes 64:3737-50.HumanSkeletal muscleObesity
Dungel 2015 Free Radic Biol Med2015Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.RatLiverIschemia-reperfusion
Oxidative stress;RONS
Yan 2015 BMC Cancer2015Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401.Human
Mouse		Genital
Other cell lines		Cancer
Lehtola 2015 Master's Thesis2015Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44.HumanBlood cells
Other cell lines
Lymphocyte
Aroor 2015 Diabetes2015Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.MouseLiverDiabetes
Harris 2015 Diabetes2015Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68.MouseSkeletal muscle
Hasli 2015 Master Thesis2015Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147.FishesHeart
Skeletal muscle		Temperature
Kluckova 2015 Methods Mol Biol2015Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94.MouseEndothelial;epithelial;mesothelial cell
Genital
Other cell lines		Cancer
Flatters 2015 Prog Mol Biol Transl Sci2015Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.RatNervous systemDiabetes
Other
Houben 2015 Mitochondrion2015Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104.HorseSkeletal muscleOther
Ofer 2015 Mol Endocrinol2015Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707.HumanGenital
Other cell lines		Cell deathCancer
Patil 2015 J Nutr Biochem2015Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.MouseSkeletal muscle
Liver
Fat
Makrecka-Kuka 2015 Biomolecules2015Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319Human
Mouse		Heart
Nervous system
HEK		Oxidative stress;RONS
Antoun 2015 JIMD Rep2015Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9.HumanSkeletal muscleMitochondrial diseaseOther
Coupling-control protocol2015Gnaiger E (2015) From PCP to CCP. Mitochondr Physiol Network 2015-01-11.
Du 2015 Aquat Toxicol2015Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40.FishesLiver
Miwa 2015 Free Radic Biol Med2015Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays. Free Radic Biol Med 90:173-83.MouseLiverOxidative stress;RONS
Errea 2015 J Neuroinflammation2015Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152.MouseNervous systemOxidative stress;RONSOther
Wessels 2015 Am J Physiol2015Wessels B, van den Broek NM, Ciapaite J, Houten SM, Wanders RJA, Nicolay K, Prompers JJ (2015) Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo. Am J Physiol 309(7):E670-8.RatSkeletal muscleObesity
Nelson 2015 Master Thesis2015Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53.Mouse
Rat		Heart
Other cell lines		Cardiovascular
Diabetes
Jeger 2015 BioMed Res Internat2015Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.HumanSkeletal muscle
Liver
Other cell lines		Sepsis
Hansen 2015 Obesity (Silver Spring)2015Hansen M, Lund MT, Gregers E, KraunsĂže R, Van Hall G, Helge JW, Dela F (2015) Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB. Obesity (Silver Spring) 23:2022-9.HumanFatDiabetes
Obesity
Hezel 2015 Redox Biol2015Hezel MP, Liu M, Schiffer TA, Larsen FJ, Checa A, Wheelock CE, Carlström M, Lundberg JO, Weitzberg E (2015) Effects of long-term dietary nitrate supplementation in mice. Redox Biol 5:234-42.MouseSkeletal muscleOxidative stress;RONS
Mourier 2015 J Cell Biol2015Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42.MouseHeart
Fibroblast
Hwang 2015 EMBO Mol Med2015Hwang S, Disatnik MH, Mochly-Rosen D (2015) Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med 7:1307-26.RatNervous system
Other cell lines		Cell deathNeurodegenerative
Other
Ziak 2015 Mitochondrion2015Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.HumanSkeletal muscle
Chu 2015 Liver Transpl2015Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.RatLiverIschemia-reperfusion
Vincent 2015 Front Physiol2015Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51.HumanSkeletal muscle
Moore 2015 PhD Thesis2015Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.RatLiverCryopreservation
Beier 2015 FASEB J2015Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3âș T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409MouseNervous system
Bock 2015 Thesis2015Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80.MouseLung;gill
Macrophage-derived		Oxidative stress;RONS
Rodrigues 2015 J Cell Biochem2015Rodrigues MF, Carvalho É, Pezzuto P, Rumjanek FD, AmoĂȘdo ND (2015) Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin a on the energy metabolism of breast cancer cells. Int J Biochem Cell Biol 116:797-808.HumanEndothelial;epithelial;mesothelial cell
Other cell lines		Cancer
Woodlief 2015 Obesity (Silver Spring)2015Woodlief TL, Carnero EA, Standley RA, Distefano G, Anthony SJ, Dubis GS, Jakicic JM, Houmard JA, Coen PM, Goodpaster BH (2015) Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. Obesity (Silver Spring) 23:2454-61.HumanSkeletal muscleDiabetes
Obesity
Canto 2015 Curr Protoc Mouse Biol2015CantĂł C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.MouseHeart
Skeletal muscle
Nervous system
Liver
Fat
Schoettl 2015 Endocrinology2015Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33.MouseFatOxidative stress;RONS
Du 2015 J Biol Chem2015Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710.MouseNervous system
Islet cell;pancreas;thymus
Hansson 2015 Eur J Pharmacol2015Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19.PigHeartIschemia-reperfusion
Temperature
Ramos-Filho 2015 PLoS One2015Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766.RatSkeletal muscle
Dahl 2015 Acta Physiol (Oxf)2015Dahl R, Larsen S, Dohlmann TL, Qvortrup K, Helge JW, Dela F, Prats C (2015) Three dimensional reconstruction of the human skeletal muscle mitochondrial network as a tool to assess mitochondrial content and structural organization. Acta Physiol (Oxf) 213:145-55.HumanSkeletal muscle
Soares 2015 PLoS One2015Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600.HexapodsSkeletal muscleOxidative stress;RONS
Tartaro 2015 Transplant Proc2015TĂĄrtaro RD, Jorge GD, Leonardi MI, Escanhoela CA, Leonardi LS, Boin IF (2015) No protective function found in Wistar rats submitted to long ischemia time and reperfusion after intermittent clamping of the total hepatic pedicle. Transplant Proc 47:1038-41.RatLiverIschemia-reperfusion
Wessels 2015 Diabetes Obes Metab2015Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60.RatSkeletal muscleDiabetes
Obesity
Tan 2015 Cell Metab2015Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94.Human
Mouse		Endothelial;epithelial;mesothelial cell
Genital
Other cell lines		Cancer
Gnaiger 2015 Scand J Med Sci Sports2015Gnaiger E, Boushel R, SĂžndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, DĂ­ez-SĂĄnchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612HumanSkeletal muscleTemperature
Schirris 2015 Cell Metab2015Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407.Human
Mouse		Skeletal muscle
Other cell lines		Myopathy
Torelli 2015 Free Radic Biol Med2015Torelli NQ, Ferreira-JĂșnior JR, Kowaltowski AJ, da Cunha FM (2015) RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radic Biol Med 81C:30-7.Saccharomyces cerevisiae
Hansen 2015 Shock2015Hansen ME, Simmons KJ, Tippetts TS, Thatcher MO, Saito RR, Hubbard ST, Trumbull AM, Parker BA, Taylor OJ, Bikman BT (2015) Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism. Shock 44:585-92.MouseSkeletal muscle
Other cell lines
Ehinger 2015 J Neurol2015Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503.HumanBlood cells
Lymphocyte
Platelet		Neurodegenerative
Other
Warne 2015 J Biol Chem2015Warne J, Pryce G, Hill JM, Shi X, LennerÄs F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.MouseLiverPermeability transitionNeurodegenerative
Krumschnabel 2015 Methods Mol Biol2015Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61.MouseNervous systemOxidative stress;RONS
Cell ergometry2015Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18.
Cahill 2015 J Biol Chem2015Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19.MouseHeartCardiovascular
Petrus 2015 Can J Physiol Pharmacol2015PetruƟ A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8.RatHeartIschemia-reperfusion
Porter 2015 Am J Physiol Endocrinol Metab2015Porter C, Hurren NM, Cotter MV, Bhattarai N, Reidy PT, Dillon EL, Durham WJ, Tuvdendorj D, Sheffield-Moore M, Volpi E, Sidossis LS, Rasmussen BB, BĂžrsheim E (2015) Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am J Physiol Endocrinol Metab 309:E224-32.HumanSkeletal muscleAging;senescence
Dueregger 2015 PLoS One2015Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704.HumanGenital
Other cell lines		Cancer
Hejzlarova 2015 Biochem J2015Hejzlarová K, Kaplanová V, NƯsková H, Kováƙová N, Jeơina P, Drahota Z, Mráček T, Seneca S, Houơtěk J (2015) Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. Biochem J 466:601-11.HumanOther cell linesMitochondrial disease
Koliaki 2015 Cell Metab2015Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46.HumanLiverDiabetes
Obesity
Other
Bonsignore 2015 Mech Ageing Dev2015Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52.MouseLiver
Rodrigues 2016 Biochem J2015Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645MouseEndothelial;epithelial;mesothelial cell
Other cell lines		Cancer
Fouret 2015 Biochim Biophys Acta2015Fouret G, Tolika E, Lecomte J, Bonafos B, Aoun M, Murphy MP, Ferreri C, Chatgilialoglu C, Dubreucq E, Coudray C, Feillet-Coudray C (2015) The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats. Biochim Biophys Acta 1847:1025-35.RatLiver
Burtscher 2015 Mitochondrion2015Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.MouseNervous systemNeurodegenerative
Lark 2015 Front Physiol2015Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332MouseSkeletal muscle
Liver
Schoettl 2015 Mol Metab2015Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42.MouseFat
Other cell lines		Obesity
Hagl 2015 J Alzheimers Dis2015Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38.RatNervous system
Kidney
Other cell lines		Alzheimer's
Ping 2015 Oxid Med Cell Longev2015Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1đ›Œâ€“NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825.RatHeart
Christiansen 2015 Am J Physiol Heart Circ Physiol2015Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47.CatHeart
Skeletal muscle		Oxidative stress;RONSCardiovascular
Kishita 2015 Am J Hum Genet2015Kishita Y, Pajak A, Bolar NA, Marobbio CM, Maffezzini C, Miniero DV, Monné M, Kohda M, Stranneheim H, Murayama K, Naess K, Lesko N, Bruhn H, Mourier A, Wibom R, Nennesmo I, Jespers A, Govaert P, Ohtake A, Van Laer L, Loeys BL, Freyer C, Palmieri F, Wredenberg A, Okazaki Y, Wedell A (2015) Intra-mitochondrial methylation deficiency due to mutations in SLC25A26. Am J Hum Genet 97:761-8.HumanSkeletal muscle
Fibroblast		Inherited
Other
Sobotka 2015 Physiol Res2015Sobotka O, Drahota Z, Kučera O, Endlicher R, RauchovĂĄ H, ČervinkovĂĄ Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.RatLiver
Hollis 2015 Proc Natl Acad Sci U S A2015Hollis F, van der Kooij MA, Zanoletti O, Lozano L, CantĂł C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.RatNervous system
Imran 2015 J Neurochem2015Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18.RatNervous systemOther
Drechsler 2015 Intensive Care Medicine Experimental2015Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.MouseLiver
Kidney		Sepsis
Hanssen 2015 Diabetes2015Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes 65:1179-89.HumanSkeletal muscleTemperatureObesity
Khera 2015 Placenta2015Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9.HumanGenital
Other cell lines
Kruse 2015 Aging Cell2015Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99.MouseSkeletal muscleOxidative stress;RONSAging;senescence
Bowen 2015 Eur J Heart Fail2015Bowen TS, Rolim NP, Fischer T, Baekkerud FH, Medeiros A, Werner S, BrĂžnstad E, Rognmo O, Mangner N, Linke A, Schuler G, Silva GJ, WislĂžff U, Adams V (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail 17:263-72.RatSkeletal muscleCardiovascular
Seillier 2015 EMBO Mol Med2015Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18.Human
Mouse		FibroblastOxidative stress;RONSDiabetes
Obesity
Other
Van Hoose 2015 Thesis2015Van Hoose P (2015) Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. Dissertations p128.MouseHeartIschemia-reperfusionCardiovascular
Kelly 2015 Biotechnol J2015Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40.CHO
Assmann 2014 PhD Thesis2015Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111.PigKidney
Other cell lines		Other
Porter 2015 Burns2015Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics. Burns 42:112-22.MouseSkeletal muscleCell deathOther
Hendricks 2015 Thesis2015Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67.MouseNervous systemAging;senescence
Alzheimer's
Fritsch 2015 Am J Clin Nutr2015Fritsch M, Koliaki C, Livingstone R, Phielix E, Bierwagen A, Meisinger M, Jelenik T, Strassburger K, Zimmermann S, Brockmann K, Wolff C, Hwang JH, Szendroedi J, Roden M (2015) Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients. Am J Clin Nutr 102:1051-8.HumanSkeletal muscleDiabetes
Obesity
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sånchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.Oxidative stress;RONS
Li 2015 Sci Rep2015Li P, Wang B, Sun F, Li Y, Li Q, Lang H, Zhao Z, Gao P, Zhao Y, Shang Q, Liu D, Zhu Z (2015) Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failure. Sci Rep 5:10229.HumanBlood cells
Lymphocyte		Oxidative stress;RONSCardiovascular
Hagl 2015 Molecules2015Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39.RatNervous system
Other cell lines
Christiansen 2015 J Vet Med Sci2015Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75.CatHeart
Skeletal muscle
Labieniec-Watala 2015 Int J Pharm Sci Res2015Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106.RatHeartCardiovascular
Diabetes
Irving 2015 J Clin Endocrinol Metab2015Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS (2015) Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab 100:1654-63.HumanSkeletal muscle
Van de Weijer 2015 Diabetes2015van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201.HumanSkeletal muscleDiabetes
Hanssen 2015 Nat Med2015Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P (2015) Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nat Med 21:863-5.HumanSkeletal muscleTemperatureDiabetes
Kilbaugh 2015 Exp Neurol2015Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144.PigNervous systemNeurodegenerative
Other
Banerjee 2015 Placenta2015Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32.HumanGenitalOxidative stress;RONS
Weidinger 2015 Antioxid Redox Signal2015Weidinger A, MĂŒllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.RatLiverOxidative stress;RONS
Kruska 2015 Biochim Biophys Acta2015Kruska N, Schönfeld P, Pujol A, Reiser G (2015) Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions. Biochim Biophys Acta 1852:925-36.MouseNervous systemOxidative stress;RONSOther
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol2015Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55.FishesHeartTemperature
Sjoevall 2014 PLoS One2014Sjövall F, Morota S, Asander Frostner E, Hansson Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function. PLoS One 9:e97673.HumanBlood cells
Platelet		Sepsis
Castelein 2014 Exp Gerontol2014Castelein N, Muschol M, Dhondt I, Cai H, De Vos WH, Dencher NA, Braeckman BP (2014) Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans. Exp Gerontol 56:26-36.Caenorhabditis elegansAging;senescence
Valenti 2014 Anal Biochem2014Valenti D, de Bari L, De Filippis B, Ricceri L, Vacca RA (2014) Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas. Anal Biochem 444:25-31.MouseNervous systemCryopreservation
Ischemia-reperfusion
Hasenour 2014 J Biol Chem2014Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-ÎČ-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9.MouseLiver
Solinas 2014 Mech Ageing Dev2014Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4.RatKidney
Broeker 2014 Thesis2014Broeker C (2014) Mitochondriopathien als Ursache des renalen Fanconi-Syndroms. Dissertation 85pp.PigKidney
Other cell lines		Other
Thatcher 2014 Am J Physiol Endocrinol Metab2014Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT (2014) Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab 307:E919-27.Human
Mouse		Skeletal muscleDiabetes
Miquel 2014 Free Radic Biol Med2014Miquel E, Cassina A, MartĂ­nez-Palma L, Souza JM, Bolatto C, RodrĂ­guez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P (2014) Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radic Biol Med 70:204-13.MouseSkeletal muscle
Nervous system		Neurodegenerative
Wessels 2014 PLoS One2014Wessels B, Ciapaite J, van den Broek NMA, Nicolay K, Prompers JJ (2014) Metformin impairs mitochondrial function in skeletal muscle of both lean and diabetic rats in a dose-dependent manner. PLoS One 9:e100525.RatSkeletal muscleDiabetes
Zachariah 2014 Diabetes2014Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR (2014) Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes 63:1560-71.MouseSkeletal muscleDiabetes
Obesity
Tippets 2014 BMC Cardiovasc Disord2014Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT (2014) Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 14:165.Mouse
Rat		Heart
Other cell lines		Oxidative stress;RONSOther
Grimpo 2014 Comp Biochem Physiol A Mol Integr Physiol2014Grimpo K, Kutschke M, Kastl A, Meyer CW, Heldmaier G, Exner C, Jastroch M (2014) Metabolic depression during warm torpor in the Golden spiny mouse (Acomys russatus) does not affect mitochondrial respiration and hydrogen peroxide release. Comp Biochem Physiol A Mol Integr Physiol 167:7-14.Other mammalsHeart
Skeletal muscle
Liver
Kidney		Temperature
Chakraborty 2014 J Cardiovasc Dis2014Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459.RatHeart
Blood cells		Cardiovascular
Serteyn 2014 Bioenergetics2014Serteyn D, de la RebiĂšre de Pouyade G, Sandersen C, Salciccia A, Grulke S, Mouithys-Mickalad A, Franck T, Lejeune JP, Ceusters Justine D (2014) Muscle mitochondrial dysfunction in horses affected by acute laminitis. Bioenergetics 3:1-7.HorseSkeletal muscleObesity
Other
Mourier 2014 Hum Mol Genet2014Mourier A, Ruzzenente B, Brandt T, KĂŒhlbrandt W, Larsson NG (2014) Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet 23:2580-92.MouseHeartOxidative stress;RONSNeurodegenerative
De Palma 2014 Skelet Muscle2014De Palma C, Morisi F, Pambianco S, Assi E, Touvier T, Russo S, Perrotta C, Romanello V, Carnio S, Cappello V, Pellegrino P, Moscheni C, Bassi MT, Sandri M, Cervia D, Clementi E (2014) Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation. Skelet Muscle 4:22.MouseSkeletal muscle
Garnol 2014 Physiol Res2014Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.RatLiverOxidative stress;RONSObesity
Ost 2014 PLoS One2014Ost M, Werner F, Dokas J, Klaus S, Voigt A (2014) Activation of AMPKa2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS One 14:e94689.MouseSkeletal muscle
Schiffer 2014 FASEB J2014Schiffer TA, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2014) Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans. FASEB J 28:4303-11.HumanSkeletal muscleIschemia-reperfusion
Hypoxia
Chu 2014 PLoS One2014Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR (2014) Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia. PLoS One 9:e100609.MouseLiverObesity
Afshordel 2014 Prostaglandins Leukot Essent Fatty Acids2014Afshordel S, Hagl S, Werner D, Roehner N, Koegel D, Bazan NG, Eckert GP (2014) Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - impact of Bcl-2 and NPD-1 like metabolites. Prostaglandins Leukot Essent Fatty Acids 92:23-31.MouseNervous systemAging;senescence
Davoudi 2014 PLoS One2014Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767.MouseLiverOther
Dogan 2014 Cell Metab2014Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69.MouseHeart
Skeletal muscle
Liver
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sånchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.MouseLiverSepsis
Chicco 2014 J Exp Biol2014Chicco AJ, Le CH, Schlater AE, Nguyen AD, Kaye SD, Beals JW, Scalzo RL, Bell C, Gnaiger E, Costa DP, Crocker DE, Kanatous SB (2014) High fatty acid oxidation capacity and phosphorylation control despite elevated leak and reduced respiratory capacity in northern elephant seal muscle mitochondria. J Exp Biol 217:2947-55.Human
Other mammals		Skeletal muscleIschemia-reperfusion
Temperature
Iglesias-Gonzalez 2014 PhD Thesis2014Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242.RatNervous systemParkinson's
Pham 2014 Am J Physiol2014Pham T, Loiselle D, Power A, Hickey AJ (2014) Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Am J Physiol 307:C499–507.RatHeartIschemia-reperfusion
Oxidative stress;RONS
Mitochondrial disease		Diabetes
Myopathy
Shama 2014 Funct Ecol2014Shama LNS, Strobel A, Mark FC, Wegner KM (2014) Transgenerational plasticity in marine sticklebacks: maternal effects mediate impacts of a warming ocean. Funct Ecol 28:1482–93.FishesHeartTemperature
Khan 2014 J Comp Physiol2014Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ (2014) Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae). J Comp Physiol 184:991-1001.FishesSkeletal muscleTemperature
Power 2014 Physiol Rep2014Power A, Pearson N, Pham T, Cheung C, Phillips A, Hickey A (2014) Uncoupling of oxidative phosphorylation and ATP synthase reversal within the hyperthermic heart. Physiol Rep pii:e12138.RatHeartTemperature
Cordero-Reyes 2014 J Mol Cell Cardiol2014Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ (2014) Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol 68:98-105.HumanHeartCardiovascular
Slinde 2014 freepatentsonline.com2014Slinde E, Egelandsdal B (2014) Meat treatment and preservation method. Freepatentsonline.com 14/128207.BovinesSkeletal muscle
Gnaiger 2014 MitoPathways2014
O2k-Protocols

Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. — see 5th edition: Gnaiger 2020 BEC MitoPathways.

Human
Mouse		Heart
Skeletal muscle
Fibroblast
Krumschnabel 2014 Methods Enzymol2014Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81. https://doi.org/10.1016/B978-0-12-416618-9.00009-1MouseNervous systemMitochondrial disease
Rossato 2014 PLoS One2014Rossato FA, Zecchin KG, La Guardia PG, Ortega RM, Alberici LC, Costa RA, Catharino RR, Graner E, Castilho RF, Vercesi AE (2014) Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic Melan-A cells associated with inhibition of mitochondrial respiration. PLoS One 9:e101060.MouseEndothelial;epithelial;mesothelial cell
Other cell lines		Cell deathCancer
DeLany 2014 J Clin Endocrinol Metab2014DeLany JP, Dube JJ, Standley RA, Distefano G, Goodpaster BH, Stefanovic-Racic M, Coen PM, Toledo FG (2014) Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity. J Clin Endocrinol Metab 99:4307-14.HumanSkeletal muscleDiabetes
Garratt 2014 Proc Natl Acad Sci U S A2014Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24.MouseLiver
Boutant 2014 Mol Metab2014Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.MouseSkeletal muscle
Liver
Fat
Van Bergen 2014 Mitochondrion2014Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33.Human
Mouse		Nervous system
Blood cells
Porter 2014 Am J Physiol2014Porter C, Herndon DN, BĂžrsheim E, Chao T, Reidy P, Borack M, Rasmussen BB, Chondronikola M, Saraf M, Sidossis LS (2014) Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults. Am J Physiol 307:E462-7.HumanSkeletal muscleOther
Dube 2014 Am J Physiol Endocrinol Metab2014Dube JJ, Coen PM, DiStefano G, Chacon AC, Helbling NL, Desimone ME, Stafanovic-Racic M, Hames KC, Despines AA, Toledo FG, Goodpaster BH (2014) Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance. Am J Physiol Endocrinol Metab 307:E1117-24.HumanSkeletal muscleDiabetes
Koenemann 2014 Dissertation2014Koenemann B (2014) Einfluss der HyperglykÀmie auf die mitochondriale Atmung von Leberzellen septischer MÀuse mit und ohne Imeglimin. PhD Thesis 1-61.MouseLiverSepsis
Abdurrachim 2014 Biochim Biophys Acta2014Abdurrachim D, Ciapaite J, Wessels B, Nabben M, Luiken JJ, Nicolay K, Prompers JJ (2014) Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochim Biophys Acta 1842:1525-37.MouseHeartObesity
Davoudi 2014 PhD Thesis2014Davoudi M (2014) Effect of experimental complex III deficiency on respiratory chain assembly and function. PhD Thesis 1-65.MouseLiver
Fletcher 2014 Med Sci Sports Exerc2014Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.RatLiver
Hagl 2014 J Alzheimers Dis b2014Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3.MouseNervous systemAlzheimer's
Piel 2014 Acta Physiol (Oxf)2014Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80.HumanBlood cells
Other cell lines
Platelet		Diabetes
Felser 2014 Toxicology II2014Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, KrĂ€henbĂŒhl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46.HumanLiver
Other cell lines		Cell death
Hoevenaars 2014 Mol Nutr Food Res2014Hoevenaars FP, Bekkenkamp-Grovenstein M, Janssen RJ, Heil SG, Bunschoten A, Hoek-van den Hil EF, Snaas-Alders S, Teerds K, van Schothorst EM, Keijer J (2014) Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences. Mol Nutr Food Res 58:799-807.MouseSkeletal muscleObesity
Rudnicki 2014 United States Patent Application Publication2014Rudnicki MA, Yin Hang (2014) MICRORNA INHIBITORS. United States Patent Application Publication 1-49.MouseSkeletal muscle
Fat		Obesity
Zambrano 2014 J Cell Biol2014Zambrano A, GarcĂ­a-Carpizo V, Gallardo ME, Villamuera R, GĂłmez-FerrerĂ­a MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A (2014) The thyroid hormone receptor induces DNA damage and premature senescence. J Cell Biol 204:129-46.Mouse
Jelenik 2014 Diabetes2014Jelenik T, SĂ©quaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67.MouseSkeletal muscle
Liver		Diabetes
Baggio 2014 Nucleic Acids Res2014Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG5 (2014) Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res 42:13920-38.Drosophila
Hexapods
Van Bree 2014 PhD Thesis2014van Bree B (2014) Mitochondria, lipotoxicity and skeletal muscle metabolism: implications for type 2 diabetes mellitus. PhD Thesis 1-150.MouseSkeletal muscleOxidative stress;RONSDiabetes
Larsen 2014 Anal Biochem2014Larsen S, KraunsĂže R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8.Human
Mouse		Skeletal muscle
Onukwufor 2013 J Exp Biol2014Onukwufor JO, Macdonald N, Kibenge F, Stevens D, Kamunde C (2013) Hypoxia-cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia-induced proton leak by low doses of cadmium. J Exp Biol 217:831-40.FishesLiverIschemia-reperfusion
Oxidative stress;RONS
Hypoxia
Fisar 2014 Toxicol Lett2014FiĆĄar Z, Singh N, HroudovĂĄ J (2014) Cannabinoid-induced changes in respiration of brain mitochondria. Toxicol Lett 231:62-71.PigNervous system
Divakaruni 2014 Curr Protoc Toxicol2014Divakaruni AS, Rogers GW, Murphy AN (2014) Measuring mitochondrial function in permeabilized cells using the Seahorse XF Analyzer or a clark-type oxygen electrode. Curr Protoc Toxicol 60:25.2.1-25.2.16.MouseSkeletal muscle
Other cell lines
Phielix 2014 Diabetologia2014Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81.HumanSkeletal muscleDiabetes
Obesity
Hirzel 2014 PhD Thesis2014Hirzel E (2014) Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies. PhD Thesis 1-106.HumanFat
Other cell lines		Obesity
Kukat 2014 PLoS Genet2014Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A (2014) Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. https://doi.org/10.1371/journal.pgen.1004385MouseHeartOxidative stress;RONS
Den Hollander 2014 Toxicol Sci2014den Hollander B, Sundström M, Pelander A, OjanperÀ I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31.MouseNervous system
Iftikar 2014 Thesis University of Auckland2014Iftikar FI (2014) Testing the role of heart mitochondrial stability and function in heart failure of ectotherms exposed to heat stress. Thesis University of Auckland:167pp.FishesHeartOxidative stress;RONS
Temperature
Ambrosio 2014 Free Radic Biol Med2014Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster BH, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A (2014) Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med 74C:64-73.MouseSkeletal muscle
Cedikova 2014 Evid Based Complement Alternat Med2014Cedikova M, Miklikova M, Stachova L, Grundmanova M, Tuma Z, Vetvicka V, Zech N, Kralickova M, Kuncova J (2014) Effects of the Czech propolis on sperm mitochondrial function. Evid Based Complement Alternat Med 248768.HumanGenital
Casanova 2014 J Nutr Biochem2014Casanova E, Baselga-Escudero L, Ribas-Latre A, CedĂł L, Arola-Arnal A, Pinent M, BladĂ© C, Arola L, SalvadĂł MJ (2014) Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats. J Nutr Biochem 25:1003–10.RatSkeletal muscleObesity
Kivelae 2014 EMBO Mol Med2014KivelÀ R, Bry M, Robciuc MR, RÀsÀnen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, MÀyrÀnpÀÀ MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21.RatHeartIschemia-reperfusionCardiovascular
Montaigne 2014 Circulation2014Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B (2014) Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in Type 2 Diabetic but not in obese patients. Circulation 130:554-64.HumanHeartDiabetes
Obesity
Beiral 2014 Cell Transplant2014Beiral HJ, Rodrigues-Ferreira C, Fernandes AM, Gonsalez SR, Mortari NC, Takiya CM, Sorenson MM, Figueiredo-Freitas C, Galina A, Vieyra A (2014) The impact of stem cells on electron fluxes, proton translocation and ATP synthesis in kidney mitochondria after ischemia/reperfusion. Cell Transplant 23:207-20.RatKidney
Stem cells		Ischemia-reperfusion
Damiano 2014 PLoS One2014Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, AuchĂšre F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, LombĂšs A (2014) Tissue- and cell-specific mitochondrial defect in Parkin- deficient mice. PLoS One 9:e99898.MouseNervous systemParkinson's
Jiroutkova 2014 Intensive Care Medicine Experimental2014Jiroutkova K, Ziak J, Krajcova A, Fric M, Dzupa V, Duska F (2014) The role of mitochondrial dysfunction in the pathophysiology of icu-acquired weakness. Intensive Care Med 2:29.HumanSkeletal muscleSepsis
Jacobs 2013 J Gerontol A Biol Sci Med Sci2013Jacobs R, Diaz V, Soldini L, Haider T, Thomassen M, Nordsborg NB, Gassmann M, Lundby C (2013) Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. J Gerontol A Biol Sci Med Sci 68:1010-22.MouseSkeletal muscleAging;senescence
Ceusters 2013 Mitochondrion2013Ceusters Justine D, Mouithys-Mickalad AA, Franck TJ, Derochette S, Vanderplasschen A, Deby-Dupont GP, Serteyn DA (2013) Effect of myeloperoxidase and anoxia/reoxygenation on mitochondrial respiratory function of cultured primary equine skeletal myoblasts. Mitochondrion 13:410-16.HorseSkeletal muscleIschemia-reperfusion
Oxidative stress;RONS
Hall 2013 Oncotarget2013Hall A, Meyle KD, Lange MK, Klima M, Sanderhoff M, Dahl C, Abildgaard C, Thorup K, Moghimi SM, Jensen PB, Bartek J, Guldberg P, Christensen C (2013) Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene. Oncotarget 4:584-99.HumanOther cell linesCancer
Rojahn 2013 Thesis Norwegian University of Life Sciences - Ås2013Rojahn L (2013) Effects of micronutrients on survival and mitochondrial viability in honey bees (Apis mellifera). Thesis Norwegian University of Life Sciences - Ås: 41 pp.HexapodsSkeletal muscle
Perales Villarroel 2013 J Surg Res2013Perales Villarroel JP, Figueredo R, Guan Y, Tomaiuolo M, Karamercan MA, Welsh J, Selak MA, Becker LB, Sims C (2013) Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function. J Surg Res 184:422-9.HumanBlood cells
Platelet		Oxidative stress;RONS
Karlsson 2013 Int J Biochem Cell Biol2013Karlsson M, Hempel C, Sjövall F, Hansson Magnus J, Kurtzhals JA, Elmér E (2013) Brain mitochondrial function in a murine model of cerebral malaria and the therapeutic effects of rhEPO. Int J Biochem Cell Biol 45:151-5.MouseNervous systemMitochondrial disease
Martinez 2013 Marine Biol2013Martinez E, Menze MA, Torres JJ (2013) Mitochondrial energetics of benthic and pelagic Antarctic teleosts. Marine Biol 160:2813-23.FishesLiver
Chu 2013 PLoS One2013Chu MJ, Phillips AR, Hosking AW, Macdonald JR, Bartlett AS, Hickey AJ (2013) Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One 8:e79097.Human
Rat		Liver
Aidt 2013 PLoS Curr2013Aidt FH, Nielsen SM, Kanters J, Pesta D, Nielsen TT, NĂžrremĂžlle A, Hasholt L, Christiansen M, Hagen CM (2013) Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model. PLoS Curr 5. pii:ecurrents.hd.d8917b4862929772c5a2f2a34ef1c201.MouseNervous systemNeurodegenerative
Zhang 2013 PLoS One2013Zhang Z, Tsukikawa M, Peng M, Polyak E, Nakamaru-Ogiso E, Ostrovsky J, McCormack S, Place E, Clarke C, Reiner G, McCormick E, Rappaport E, Haas R, Baur JA, Falk MJ (2013) Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. PLoS One 8:e69282.HumanFibroblastMitochondrial disease
Hagenbuchner 2013 Oncogene2013Hagenbuchner J, Kuznetsov AV, Obexer P, Ausserlechner MJ (2013) BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene 32:4748-57.HumanOther cell linesCell death
Pichaud 2013 J Bioenerg Biomembr2013Pichaud N, Ballard JWO, Tanguay RM, Blier PU (2013) Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration. J Bioenerg Biomembr 45:25-35.HexapodsSkeletal muscle
Sjövall 2013 Thesis Lund University - Sweden2013Sjövall F (2013) Mitochondrial function in sepsis - temporal evolvement of respiratory capacity in human blood cells. Thesis Lund University - Sweden 83pp.HumanBlood cells
Platelet		Sepsis
Hernandez-Alvarez 2013 Antioxid Redox Signal2013Hernåndez-Alvarez MI, Paz JC, Sebastiån D, Muñoz JP, Liesa M, Segalés J, Palacín M, Zorzano A (2013) Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal 19:366-78.RatLiver
Other cell lines		Oxidative stress;RONS
Stride 2013 Eur J Heart Fail2013Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F (2013) Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 15:150-7.HumanHeartMitochondrial disease
Hughey 2013 Cardiovasc Diabetol2013Hughey CC, Ma L, James FD, Bracy DP, Wang Z, Wasserman DH, Rottman JN, Hittel DS, Shearer J (2013) Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart. Cardiovasc Diabetol 12:128.MouseHeartCardiovascular
Diabetes
Mayeur 2013 PhD Thesis2013Mayeur S (2013) Retard de croissance intra-utérin et vulnérabilité au syndrome métabolique: recherche de marqueurs placentaires dans un modÚle de dénutrition maternelle prénatale et chez l'Homme. PhD Thesis 1-225.RatGenitalDiabetes
Vijgen 2013 Surg Obes Relat Dis2013Vijgen GH, Bouvy ND, Hoeks J, Wijers S, Schrauwen P, van Marken Lichtenbelt WD (2013) Impaired skeletal muscle mitochondrial function in morbidly obese patients is normalized one year after bariatric surgery. Surg Obes Relat Dis 9:936-41.HumanSkeletal muscleObesity
Hagl 2013 Pharmacol Res2013Hagl S, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP (2013) Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res 76C:17-27.Guinea pigNervous system
Cavallo 2013 PLoS One2013Cavallo A, Priore P, Gnoni GV, Papa S, Zanotti F, Gnoni A (2013) 3,5-Diiodo-L-thyronine administration to hypothyroid rats rapidly enhances fatty acid oxidation rate and bioenergetic parameters in liver cells. PLoS One 8:e52328. doi: 10.1371/journal.pone.0052328RatLiver
Pichaud 2013 J Exp Biol2013Pichaud N, Garratt M, Ballard JWO, Brooks RC (2013) Physiological adaptations to reproduction II. Mitochondrial adjustments in livers of lactating mice. J Exp Biol 216:2889-95.MouseLiver
Van der Laans 2013 J Clin Invest2013van der Lans AA, Hoeks J, Brans B, Vijgen GH, Visser MG, Vosselman MJ, Hansen J, Jörgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2013) Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest 123:3395-403.HumanSkeletal muscle
Kushnareva 2013 Cell Death Differ2013Kushnareva YE, Gerencser AA, Bossy B, Ju WK, White AD, Waggoner J, Ellisman MH, Perkins G, Bossy-Wetzel E (2013) Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity. Cell Death Differ 20:353-65.HumanEndothelial;epithelial;mesothelial cell
HeLa
Dos Santos 2013 Bio Open2013Dos Santos RS, Galina A, Da-Silva WS (2013) Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle. Bio Open 2:82-7.FishesSkeletal muscle
Segalés 2013 Am J Physiol Endocrinol Metab2013Segalés J, Paz JC, Hernåndez-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A (2013) A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab 305:1208-21.MouseSkeletal muscle
Liver
Other cell lines
Cahill 2013 Biofouling2013Cahill PL, Heasman K, Hickey A, Mountfort D, Jeffs A, Kuhajek J (2013) Screening for negative effects of candidate ascidian antifoulant compounds on a target aquaculture species, Perna canaliculus Gmelin. Biofouling 29:29-37.MolluscsLung;gill
Alandijany 2013 J Neurovirol2013Alandijany T, Kammouni W, Roy Chowdhury SK, Fernyhough P, Jackson AC (2013) Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 19:537-49.RatNervous systemOxidative stress;RONSInfectious
Dos Santos 2013 J Bioenerg Biomembr2013dos Santos RS, Peçanha FL, da-Silva WS (2013) Functional characterization of an uncoupling protein in goldfish white skeletal muscle. J Bioenerg Biomembr 45:243-51.FishesSkeletal muscle
Smith 2013 Biochem J2013Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2013) Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456:427-39.MouseSkeletal muscle
Other cell lines
Muller 2013 Exp Neurol2013Muller AP, Haas CB, Camacho-Pereira J, Brochier AW, Gnoatto J, Zimmer ER, de Souza DO, Galina A, Portela LV (2013) Insulin prevents mitochondrial generation of H2O2 in rat brain. Exp Neurol 247:66-72.RatNervous system
Strobel 2013 PLoS One2013Strobel A, Graeve M, Poertner HO, Mark FC (2013) Mitochondrial acclimation capacities to ocean warming and acidification are limited in the antarctic nototheniid fish, Notothenia rossii and Lepidonotothen squamifrons. PLoS One 8:e68865.FishesLiverTemperature
Iftikar 2013 PLoS One2013Iftikar FI, Hickey AJ (2013) Do mitochondria limit hot fish hearts? Understanding the role of mitochondrial function with heat stress in Notolabrus celidotus. PLoS One 8:e64120.FishesHeartOxidative stress;RONS
Jacobs 2013 Exp Physiol2013Jacobs R, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2013) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55.HumanSkeletal muscleIschemia-reperfusion
Sjoevall 2013 Crit Care2013Sjoevall F, Morota S, Persson J, Hansson Magnus J, Elmer E (2013) Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cells. Crit Care 17:R152.HumanBlood cellsSepsis
Wredenberg 2013 PLoS Genet2013Wredenberg A, Lagouge M, Bratic A, Metodiev MD, SpÄhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, Habermann B, Partridge L, Park CB, Larsson NG (2013) MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet 9:e1003178.Drosophila
Perevoshchikova 2013 Free Radic Biol Med2013Perevoshchikova IV, Quinlan CL, Orr AL, Gerencser AA, Brand MD (2013) Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. Free Radic Biol Med 61:298-309. doi: 10.1016/j.freeradbiomed.2013.04.006RatSkeletal muscleOxidative stress;RONS
Thompson 2013 J Surg Res2013Thompson JR, Swanson SA, Casale GP, Johanning JM, Papoutsi E, Koutakis P, Miserlis D, Zhu Z, Pipinos II (2013) Gastrocnemius mitochondrial respiration: are there any differences between men and women? J Surg Res 185:206-11.HumanSkeletal muscleAging;senescence
Manko 2013 Acta Physiol (Oxf)2013Manko BO, Manko VV (2013) Mechanisms of respiration intensification of rat pancreatic acini upon carbachol-induced Ca2+ release. Acta Physiol (Oxf) 208:387-99.RatIslet cell;pancreas;thymus
Hara 2013 Eur J Anaesthesiol2013Hara N, Karlsson M, Sjövall F, Hansson Magnus J, ElmĂ©r E, Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112.MouseNervous systemOxidative stress;RONSSepsis
Montaigne 2013 J Am Coll Cardiol2013Montaigne D, Marechal X, Lefebvre P, Modine T, Fayad G, Dehondt H, Hurt C, Coisne A, Koussa M, Remy-Jouet I, Zerimech F, Boulanger E, Lacroix D, Staels B, Neviere R (2013) Mitochondrial dysfunction as an arrhythmogenic substrate. J Am Coll Cardiol 62:1466-73.HumanHeartPermeability transition
Oxidative stress;RONS		Obesity
Other
Beaudoin 2013 Am J Physiol Regul Integr Comp Physiol2013Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC (2013) Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol 305:542-51.RatFatDiabetes
La Guardia 2013 Front Physiol2013La Guardia PG, Alberici LC, Ravagnani FG, Catharino RR, Vercesi AE (2013) Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation. Front Physiol 4:103.RatSkeletal muscleOxidative stress;RONS
Gupte 2013 Endocrinology2013Gupte AA, Minze LJ, Reyes M, Ren Y, Wang X, Brunner G, Ghosn M, Cordero-Reyes AM, Ding K, Pratico D, Morrisett J, Shi ZZ, Hamilton DJ, Lyon CJ, Hsueh WA (2013) High fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance. Endocrinology 154:2650-62.MouseHeart
Smith 2013 Thesis The University of Guelph - Canada2013Smith BK (2013) Investigations into the regulation of skeletal muscle mitochondrial metabolism. Thesis The University of Guelph - Canada 139pp.RatSkeletal muscle
Weber 2013 Thesis East Carolina University2013Weber T (2013) The effect of contractile activity and substrate challenges on metabolic flexibility in human primary myotubes. Thesis East Carolina University - USA:105 pp.HumanSkeletal muscle
Other cell lines		Obesity
Munro 2013 Aging Cell2013Munro D, Pichaud N, Paquin F, Kemeid V, Blier PU (2013) Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica: underlying mechanisms for slow aging. Aging Cell 12:5845-92.MolluscsEndothelial;epithelial;mesothelial cellOxidative stress;RONSAging;senescence
Gilliam 2013 Free Radic Biol Med2013Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Cathey BL, Neufer PD (2013) The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radic Biol Med 65:988-96.RatSkeletal musclePermeability transitionCancer
Jacobs 2013 J Appl Physiol2013Jacobs R, FlĂŒck D, Bonne TC, BĂŒrgi S, Christensen PM, Toigo M, Lundby C (2013) Improvements in exercise performance 1 with high-intensity interval training 2 coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol 115:785-93.HumanSkeletal muscle
Hall 2013 Biochim Biophys Acta2013Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM (2013) High-resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system. Biochim Biophys Acta 1827:1213-25.MouseLiver
Other cell lines		Cell death
Claiborne 2013 Thesis2013Claiborne MS (2013) Exercice Training improves exercice capacity despite present muscle mitochondrial dysfunction in the TAZ shRNA mouse model of human barth syndrome. Master's Thesis 67pp.MouseSkeletal muscleOther
Sjoevall 2013 Mitochondrion2013Sjövall F, Ehinger JK, Marelsson SE, Morota S, Asander Frostner E, Uchino H, Lundgren J, Arnbjörnsson E, Hansson Magnus J, Fellman V, Elmér E (2013) Mitochondrial respiration in human viable platelets - methodology and influence of gender, age and storage. Mitochondrion 13:7-14.HumanBlood cells
Platelet		Ischemia-reperfusionAging;senescence
Neurodegenerative
De Castro IP 2013 Cell Death Dis2013de Castro IP, Costa AC, Celardo I, Tufi R, Dinsdale D, Loh SH, Martins LM (2013) Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants. Cell Death Dis 24:e873.Drosophila
Stephenson 2013 Thesis Royal Melbourne Institute of Technology - Melbourne2013Stephenson EJ (2013) Mitochondrial function in metabolic health. Thesis Royal Melbourne Institute of Technology - Melbourne: 106pp.RatSkeletal muscle
Hroudova 2013 Mitochondrion2013Hroudová J, Fiơar Z, Kitzlerová E, Zvěƙová M, Raboch J (2013) Mitochondrial respiration in blood platelets of depressive patients. Mitochondrion 13:795-800.HumanBlood cells
Platelet		Mitochondrial diseaseNeurodegenerative
Schwarzkopf 2013 Pharmazie2013Schwarzkopf TM, Hagl S, Eckert GP, Klein J (2013) Neuroprotection by bilobalide in ischemia: improvement of mitochondrial function. Pharmazie 68:584-9.MouseNervous systemIschemia-reperfusion
Karamercan 2013 Shock2013Karamercan MA, Weiss SL, Villarroel JP, Guan Y, Werlin E, Figueredo R, Becker LB, Sims C (2013) Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation? Shock 40:476-84.RatHeart
Liver
Kidney
Blood cells
Lymphocyte		Other
Viall 2013 J Autoimmun2013Viall CA, Chen Q, Liu B, Hickey A, Snowise S, Salmon JE, Stone PR, Chamley LW (2013) Antiphospholipid antibodies internalised by human syncytiotrophoblast cause aberrant cell death and the release of necrotic trophoblast debris. J Autoimmun 47:45-57.HumanGenital
Wohlwend 2013 Thesis2013Wohlwend M (2013) Mitochondrial function in health and disease - high-resolution respirometry in rats inbred for high vs. low running capacity. Thesis Norwegian University of Science and Technology - Trondheim: 44pp.RatHeart
Skeletal muscle
Goo 2013 Clin Exp Pharmacol Physiol2013Goo S, Pham T, Han JC, Nielsen P, Taberner A, Hickey A, Loiselle D (2013) Multiscale measurement of cardiac energetics. Clin Exp Pharmacol Physiol 40:671-81.RatHeartOxidative stress;RONS
Zeh 2013 Thesis2013Zeh RM (2013) Neurological and molecular biological characterisation of the mutant mouse line Tom40. Thesis Technische UniversitĂ€t MĂŒnchen 243pp.RatHeart
Nervous system
Schneeberger 2013 Cell2013Schneeberger M, Dietrich MO, Sebastiån D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87.MouseNervous systemObesity
Trumbeckaite 2013 Mitochondrion2013Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN (2013) Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801. Mitochondrion 13:539–47.RatNervous systemIschemia-reperfusion
Costa 2013 Cell Death Dis2013Costa AC, Loh SH, Martins LM (2013) Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467.DrosophilaParkinson's
Glancy 2013 Biochemistry2013Glancy B, Willis WT, Chess DJ, Balaban RS (2013) Effect of calcium on the oxidative phosphorylation cascade in skeletal muscle mitochondria. Biochemistry 52:2793-809.Skeletal muscle
Votion 2012 PLoS One2012Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One 7:e34890. https://doi.org/10.1371/journal.pone.0034890HorseSkeletal muscleIschemia-reperfusionObesity
Boushel 2012 Am J Physiol Regul Integr Comp Physiol2012Boushel RC, Fuentes T, Hellsten Y, Saltin B (2012) Opposing effects of nitric oxide and prostaglandin inhibition on muscle mitochondrial VO2 during exercise . Am J Physiol Regul Integr Comp Physiol 303:94-100.HumanSkeletal muscleOxidative stress;RONS
Hughey 2012 Cell Regen (Lond)2012Hughey CC, Alfaro MP, Belke DD, Rottman JN, Young PP, Wasserman DH, Shearer J (2012) Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells. Cell Regen (Lond) 1:3.Mouse
Rat		Heart
Stem cells		Ischemia-reperfusionCardiovascular
Oellermann 2012 J Exp Biol2012Oellermann M, Poertner HO, Mark FC (2012) Mitochondrial dynamics underlying thermal plasticity of cuttlefish (Sepia officinalis) hearts. J Exp Biol 215:2992-3000.MolluscsHeartIschemia-reperfusion
Kumari 2012 PLoS One2012Kumari S, Mehta SL, Li PA (2012) Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium. PLoS One 7:e39382.MouseNervous system
Other cell lines		Oxidative stress;RONS
Iglesias-Gonzalez 2012 Neurochem Res2012Iglesias-Gonzalez J, Sanchez-Iglesias S, Mendez-Alvarez E, Rose S, Hikima A, Jenner P, Soto-Otero R (2012) Differential toxicity of 6-hydroxydopamine in SH-SY5Y human neuroblastoma cells and rat brain mitochondria: protective role of catalase and superoxide dismutase. Neurochem Res 37:2150-60.RatNervous systemOxidative stress;RONS
Mitochondrial disease		Neurodegenerative
Parkinson's
Jacobs 2012 FASEB J2012Jacobs R, Siebenmann C, Hug M, Toigo M, Meinild AK, Lundby C (2012) Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria. FASEB J 90:5192-200.HumanSkeletal muscleIschemia-reperfusion
Moon 2012 J Biol Chem2012Moon SH, Jenkins CM, Kiebish MA, Sims HF, Mancuso DJ, Gross RW (2012) Genetic ablation of calcium-independent phospholipase A2Îł (iPLA2Îł) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release. J Biol Chem 287:29837-50.MouseLiverCell death
Permeability transition
Brown 2012 Am J Physiol Regul Integr Comp Physiol2012Brown JC, Chung DJ, Belgrave KR, Staples JF (2012) Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. Am J Physiol Regul Integr Comp Physiol 302:R15-28.Other mammalsSkeletal muscle
Liver		Oxidative stress;RONS
Temperature
Thiede 2012 Biochim Biophys Acta2012Thiede A, Gellerich FN, Schönfeld P, Siemen D (2012) Complex effects of 17ÎČ-estradiol on mitochondrial function. Biochim Biophys Acta 1817:1747-53.RatNervous system
Liver
Cumero 2012 Br J Pharmacol2012Cumero S, Fogolari F, Domenis R, Zucchi R, Mavelli I, Contessi S (2012) F0F1-ATPsynthase as a molecular target of 3-Iodothyronamine. Br J Pharmacol 166:2331-47Heart
Hoeks 2012 J Cell Physiol2012Hoeks J, Arany Z, Phielix E, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) Enhanced lipid -but not carbohydrate- supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice. J Cell Physiol 227:1026-33.MouseSkeletal muscleOxidative stress;RONS
Jacobs 2012 J Appl Physiol2012Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol 114:344-50.HumanSkeletal muscle
Stephenson 2012 Am J Physiol Endocrinol Metab2012Stephenson EJ, Camera DM, Jenkins TA, Lee JS, Kosari S, Hawley JA, Stepto NK (2012) Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet. Am J Physiol Endocrinol Metab 302:E1541-49.RatSkeletal muscleObesity
Hroudova 2012 European Psychiatry2012Hroudova J, Fisar Z, Korabecny J, Kuca K, Jirak R, Raboch J (2012) P-451 - changes of cellular respiration in patients with Alzheimer's disease. European Psychiatry 27:01.HumanBlood cells
Platelet		Alzheimer's
Neurodegenerative
Larsen 2012 J Physiol2012Larsen S, Nielsen J, Neigaard Nielsen C, Nielsen LB, Wibrand F, Stride N, Schroder HD, Boushel RC, Helge JW, Dela F, Hey-Mogensen M (2012) Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects. J Physiol 590:3349-60.HumanSkeletal muscle
Aoun 2012 Br J Nutr2012Aoun M, Feillet-Coudray C, Fouret G, Chabi B, Crouzier D, Ferreri C, Chatgilialoglu C, Wrutniak-Cabello C, Cristol JP, Carbonneau MA, Coudray C (2012) Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns. Br J Nutr 107:647-59.RatLiverOther
Kwak 2012 Free Radic Biol Med2012Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207.HumanSkeletal muscle
Other cell lines		Cell death
Oxidative stress;RONS
Correa 2012 Crit Care Med2012CorrĂȘa TD, Vuda M, Blaser AR, Takala J, Djafarzadeh S, DĂŒnser MW, Silva E, Lensch M, Wilkens L, Jakob SM (2012) Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Crit Care Med 40:2841-9.PigHeart
Skeletal muscle
Nervous system
Liver		Sepsis
Jose 2012 Thesis2012Jose C (2012) RÎle des mitochondries dans la tumorigénÚse: implications pour le traitement du cancer. PhD Thesis 272.HumanOther cell lines
HeLa		Cancer
Lemieux 2012 J Bioenerg Biomembr2012Lemieux H, Warren BE (2012) An animal model to study human muscular diseases involving mitochondrial oxidative phosphorylation. J Bioenerg Biomembr 44:503-12.Other invertebrates
Stephenson 2012 J Appl Physiol (1985)2012Stephenson EJ, Stepto NK, Koch LG, Britton SL, Hawley JA (2012) Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1? J Appl Physiol (1985) 113:1403-12.RatSkeletal muscle
Hroudova 2012 Toxicol Lett2012Hroudova J, Fisar Z (2012) In vitro inhibition of mitochondrial respiratory rate by antidepressants. Toxicol Lett 213:345-52.PigNervous systemOxidative stress;RONS
Leuner 2012 Mol Neurobiol2012Leuner K, Schulz K, SchĂŒtt T, Pantel J, Prvulovic D, Rhein V, Savaskan E, Czech C, Eckert A, MĂŒller WE (2012) Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytes. Mol Neurobiol 46:194-204.HumanBlood cells
Lymphocyte		Aging;senescence
Alzheimer's
Neurodegenerative
Correa 2012 Mitochondrion2012Correa CC, Aw WC, Melvin RG, Pichaud N, Ballard JWO (2012) Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster. Mitochondrion 12:459-64.Drosophila
Hexapods		Skeletal muscleAging;senescence
Pesta 2012 Methods Mol Biol2012Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol 810:25-58. https://doi.org/10.1007/978-1-61779-382-0_3HumanSkeletal muscle
Other cell lines
HEK
Fibroblast
HUVEC
Duicu 2012 Rev Med Chir Soc Med Nat Iasi2012Duicu O, Gheorgheosu D, Mirica N, Trancota S, Cristina D, Fira-Mladinescu O, Muntean D (2012) High-resolution respirometry with multiple substrates titration in permeabilized myocardial fibers. Rev Med Chir Soc Med Nat Iasi 116:207-13.RatHeart
Wuest 2012 Am J Physiol Heart Circ Physiol2012Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411.RatSkeletal muscleCryopreservation
Silva 2012 PLOS ONE2012Silva da Costa L, Pereira da Silva AP, Da Poian AT, El-Bacha T (2012) Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death. PLoS One 7:e33871.MouseNeuroblastomaMitochondrial disease
Djafarzadeh 2012 PLoS One2012Djafarzadeh S, Vuda M, Takala J, Jakob SM (2012) Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS One 7:e45195.HumanLiverSepsis
Chowdhury 2012 Brain2012Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P (2012) Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes. Brain 135:1751-66.Mouse
Rat		Nervous systemDiabetes
Neurodegenerative
Akude 2011 Diabetes2011Akude E, Zherebitskaya E, Chowdhury SK, Smith DR, Dobrowsky RT, Fernyhough P (2011) Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Diabetes 60:288-97.RatNervous systemDiabetes
Jacobs 2011 J Appl Physiol2011Jacobs R, Rasmussen P, Siebenmann C, Díaz V, Pesta D, Gnaiger E, Nordsborg NB, Robach P, Lundby C (2011) Determinants of time trial performance and maximal incremental exercise in highly trained endurance athletes. J Appl Physiol 111:1422–30.HumanSkeletal muscleIschemia-reperfusion
Amoedo 2011 PLoS One2011Amoedo ND, Rodrigues MF, Pezzuto P, Galina A, da Costa RM, de Almeida FC, El-Bacha T, Rumjanek FD (2011) Energy metabolism in h460 lung cancer cells: effects of histone deacetylase inhibitors. PLoS One 6:e22264.HumanLung;gillCancer
Guillet 2011 FASEB J2011Guillet V, Gueguen N, Cartoni R, Chevrollier A, Desquiret V, Angebault C, Amati-Bonneau P, Procaccio V, Bonneau D, Martinou JC, Reynier P (2011) Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. FASEB J 25:1618-27.MouseNervous system
Eberhart 2011 Biochim Biophys Acta2011Eberhart K, Rainer J, Bindreither D, Ritter I, Gnaiger E, Kofler R, Oefner PJ, Renner K (2011) Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia. Biochim Biophys Acta 1807:719-25.HumanBlood cellsCancer
Lemieux 2011 Int J Biochem Cell Biol2011Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. https://doi.org/10.1016/j.biocel.2011.08.008HumanHeartIschemia-reperfusionCardiovascular
Pesta 2011 Am J Physiol Regul Integr Comp Physiol2011Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87.HumanSkeletal muscleHypoxiaObesity
Pecinova 2011 Mitochondrion2011Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8.RatHeart
Nervous system
Liver
Kidney
Zangl 2011 Thesis UniversitĂ€t Ulm - Germany2011Zangl Q (2011) Funktion hepatischer Mitochondrien nach IschĂ€mie-Reperfusion und vorheriger Behandlung mit Schwefelwasserstoff im Großtierversuch. Thesis UniversitĂ€t Ulm - Germany 69pp.PigLiverIschemia-reperfusion
Strub 2011 FASEB J2011Strub GM, Paillard M, Liang J, Gomez L, Allegood JC, Hait NC, Maceyka M, Price MM, Chen Q, Simpson DC, Kordula T, Milstien S, Lesnefsky EJ, Spiegel S (2011) Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate Complex IV assembly and respiration. FASEB J 25:600-12.MouseHeart
Pajuelo-Reguera 2011 Br J Nutr2011Pajuelo-Reguera D, Quesada H, Díaz S, Fernåndez-Iglesias A, Arola-Arnal A, Bladé C, Salvadó J, Arola L (2011) Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats. Br J Nutr 28:1-9.RatFatObesity
Lim 2011 PloS One2011Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-ÎČ-mediated deregulation of estradiol. PloS One 6:e28887.HumanNeuroblastomaOxidative stress;RONSAlzheimer's
Neurodegenerative
Timmers 2011 Cell Metab2011Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P (2011) Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22.HumanSkeletal muscleObesity
Anderson 2011 Am J Physiol Heart Circ Physiol2011Anderson EJ, Rodriguez E, Anderson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol 300:H118-24.HumanHeartOxidative stress;RONSDiabetes
Bratic 2011 PLoS Genet2011Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG (2011) The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet 7:e1002324.Drosophila
Lauritzen 2010 Mol Cell Biol2010Lauritzen KH, Moldestad O, Eide L, Carlsen H, Nesse G, Storm JF, Mansuy IM, Bergersen LH, Klungland A (2010) Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior. Mol Cell Biol 30:1357-67.MouseNervous systemMitochondrial disease
Van den Berg 2010 Metabolism2010van den Berg SA, Nabben M, Bijland S, Voshol PJ, van Klinken JB, Havekes LM, Romijn JA, Hoeks J, Hesselink MK, Schrauwen P, van Dijk KW (2010) High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice. Metabolism 59:1612-8.MouseSkeletal muscle
Smolkova 2010 J Bioenerg Biomembr2010SmolkovĂĄ K, Bellance N, Scandurra F, GĂ©not E, Gnaiger E, PlecitĂĄ-HlavatĂĄ L, JeĆŸek P, Rossignol R (2010) Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. https://doi.org/10.1007/s10863-009-9267-xHumanFibroblastCancer
Hoeks 2010 Diabetes2010Hoeks J, van Herpen NA, Mensink M, Moonen-Kornips E, van Beurden D, Hesselink MK, Schrauwen P (2010) Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 59:2117-25.HumanSkeletal muscleDiabetes
Fernyhough 2010 Expert Rev Endocrinol Metab2010Fernyhough P, Roy Chowdhury SK, Schmidt RE (2010) Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Rev Endocrinol Metab 5:39-49.RatNervous systemDiabetes
Hansson 2010 J Biol Chem2010Hansson Magnus J, Morota S, Teilum M, Mattiasson G, Uchino H, Elmer E (2010) Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume. J Biol Chem 285:741-50.RatNervous systemIschemia-reperfusion
Permeability transition
Sjoevall 2010 Crit Care2010Sjoevall F, Morota S, Hansson Magnus J, Friberg H, Gnaiger E, Elmer E (2010) Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 14:R214.HumanBlood cells
Platelet		Sepsis
Kotarsky 2010 Mitochondrion2010Kotarsky H, Karikoski R, Mörgelin M, Marjavaara S, Bergman P, Zhang DL, Smet J, van Coster R, Fellman V (2010) Characterization of complex III deficiency and liver dysfunction in GRACILE syndrome caused by a BCS1L mutation. Mitochondrion 10:497-509.HumanFibroblastInherited
Verschoor 2010 PLoS One2010Verschoor ML, Wilson LA, Verschoor CP, Singh G (2010) Ets-1 regulates energy metabolism in cancer cells. PLoS One 5: e13565.HumanCancer
Baron 2010 Thesis2010Baron M (2010) Copy number variations of the mitochondrial DNA as potential cause of mitochondrial diseases. Thesis Rheinischen Friedrich-Wilhelms-Universitaet Bonn, Mathematisch-Naturwissenschaftlichen FakultÀt, 110pp.HumanEndothelial;epithelial;mesothelial cell
Fibroblast		Mitochondrial disease
Guitart 2010 J Biol Chem2010Guitart T, Leon Bernardo T, Sagalés J, Stratmann T, Bernués J, Ribas de Pouplana L (2010) New aminoacyl-tRNA synthetase-like protein in insecta with an essential mitochondrial function. J Biol Chem 285:38157-66.Drosophila
Hexapods
Hilton 2010 J Comp Physiol B2010Hilton Z, Clements KD, Hickey AJ (2010) Temperature sensitivity of cardiac mitochondria in intertidal and subtidal triplefin fishes. J Comp Physiol B 180:979-90.FishesHeart
Kane 2010 Free Radic Biol Med2010Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7.RatSkeletal muscleOxidative stress;RONS
Mitochondrial disease		Diabetes
Votion 2010 Equine Vet J2010Votion DM, Fraipont A, Goachet AG, Robert C, van Erck E, Amory H, Ceusters Justine D, de la RebiĂšre de Pouyade G, Franck T, Mouithys-Mickalad A, Niesten A, Serteyn D (2010) Alterations in mitochondrial respiratory function in response to endurance training and endurance racing. Equine Vet J 42 Suppl 38:268-74.HorseSkeletal muscle
Scandurra 2010 Adv Exp Med Biol2010Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics. https://doi.org/10.1007/978-1-4419-1241-1_2MouseBlood cells
Remels 2010 Mol Cell Endocrinol2010Remels AH, Langen RC, Schrauwen P, Schaart G, Schols AM, Gosker HR (2010) Regulation of mitochondrial biogenesis during myogenesis. Mol Cell Endocrinol 315:113-20.Mouse
Rat		Skeletal muscle
Other cell lines
Pichaud 2010 J Exp Biol2010Pichaud N, Chatelain EH, Ballard JWO, Tanguay R, Morrow G, Blier PU (2010)Thermal sensitivity of mitochondrial metabolism in two distinct mitotypes of Drosophila simulans: Evaluation of mitochondrial plasticity. J Exp Biol 213:1665-75.DrosophilaSkeletal muscle
Flamment 2009 Am J Physiol Endocrinol Metab2009Flamment M, Gueguen N, Wetterwald C, Simard G, MalthiĂšry Y, Ducluzeau PH (2009) Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 297:E1162-70.RatLiver
Pereira 2009 Biochem J2009Pereira da Silva AP, El-Bacha T, Kyaw N, dos Santos RS, Da Silva WS, Almeida FC, Da Poian AT, Galina A (2009) Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate. Biochem J 417:717-26.HumanLiverCancer
Rhein 2009 Proc Natl Acad Sci U S A2009Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A 106:20057-62.MouseNervous system
Holmuhamedov 2009 Arch Biochem Biophys2009Holmuhamedov E, Lemasters JJ (2009) Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Arch Biochem Biophys 481:226-33. https://doi.org/10.1016/j.abb.2008.10.036Liver
Tahara 2009 Free Radic Biol Med2009Tahara EB, Navarete FD, Kowaltowski AJ (2009) Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med 46:1283-97.RatHeart
Skeletal muscle
Nervous system
Liver
Kidney		Oxidative stress;RONS
Gnaiger 2009 Int J Biochem Cell Biol2009Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45. https://doi.org/10.1016/j.biocel.2009.03.013Human
Mouse		Skeletal muscleAging;senescence
Obesity
Menna-Barreto 2009 Free Radic Biol Med2009Menna-Barreto RF, Goncalves RL, Costa EM, Silva RS, Pinto AV, Oliveira MF, de Castro SL (2009) The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction. Free Radic Biol Med 47:644-53.ProtistsOxidative stress;RONS
Keeney 2009 Hum Gene Ther2009Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907.HumanNervous system
Neuroblastoma		Parkinson's
Samper 2009 Free Radic Biol Med2009Samper E, Morgado L, Estrada JC, Bernad A, Hubbard A, Cadenas S, Melov S (2009) Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas. Free Radic Biol Med 46:387-96.Oxidative stress;RONSCancer
Anderson 2009 J Am Coll Cardiol2009Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8.HumanHeartOxidative stress;RONS
Mitochondrial disease		Aging;senescence
Diabetes
Lim 2009 PlosOne2009Lim S, Ahn SY, Song IC, Chung MH, Jang HC, Park KS, Lee KU, Pak YK, Lee HK (2009) Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PLoS One 4:e5186.RatSkeletal muscle
Liver		Mitochondrial disease
Ahting 2009 Biochim Biophys Acta2009Ahting U, Floss T, Uez N, Schneider-Lohmar I, Becker L, Kling E, Iuso A, Bender A, de Angelis MH, Gailus-Durner V, Fuchs H, Meitinger T, Wurst W, Prokisch H, Klopstock T (2009) Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta 1787:371-76.MouseStem cellsOther
Kwon 2009 Thesis2009Kwon OS (2009) Effect of acute exercise or fasting on mitochondrial function and high fat diet-induced insulin resistance. PhD Thesis 46.RatSkeletal muscle
Anderson 2009 J Clin Invest2009Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81.Human
Mouse
Rat		Skeletal muscleOxidative stress;RONSDiabetes
Plecita-Hlavata 2009 Int J Biochem Cell Biol2009Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707.Rat
Human		Liver
Other cell lines		Oxidative stress;RONS
Aragones 2008 Nat Genet2008Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, K Harten S, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger Erich, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 40:170-80.MouseSkeletal muscleIschemia-reperfusion
Oxidative stress;RONS
Cannon 2008 Methods Mol Biol2008Cannon B, Nedergaard J (2008) Studies of thermogenesis and mitochondrial function in adipose tissues. Methods Mol Biol 456:109-21.Endothelial;epithelial;mesothelial cell
Hansson 2008 Free Radic Biol Med2008Hansson Magnus J, MÄnsson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A, Elmér E (2008) Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 45:284-94.RatNervous system
Liver		Ischemia-reperfusion
Oxidative stress;RONS
Mitochondrial disease
Rosca 2008 Cardiovasc Res2008Rosca MG, Vazquez EJ, Kerner J, Parland W, Chandler MP, Stanley W, Sabbah HN, Hoppel CL (2008) Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc Res 80:30-39.DogHeart
Liem 2008 Transl Res2008Liem D, Manintveld O, Schoonderwoerd K, McFalls E, Heinen A, Verdouw P, Sluiter W, Duncker D (2008) Ischemic preconditioning modulates mitochondrial respiration, irrespective of the employed signal transduction pathway. Transl Res 151:17-26.RatHeartIschemia-reperfusion
Arruda 2008 Endocrinology2008Arruda AP, Ketzer LA, Nigro M, Galina A, Carvalho DP, de Meis L (2008) Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production. Endocrinology 149:6262-71.RabbitSkeletal muscle
Phielix 2008 Physiol Behav2008Phielix E, Mensink M (2008) Type 2 diabetes mellitus and skeletal muscle metabolic function. Physiol Behav 94:252-8.Skeletal muscleDiabetes
Hoeks 2008 FEBS Lett2008Hoeks J, Briedé JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16.RatSkeletal muscleOxidative stress;RONSObesity
El-Bacha 2007 Biochim Biophys Acta2007El-Bacha T, Midlej V, Pereira da Silva AP, Silva da Costa L, Benchimol M, Galina A, Da Poian AT (2007) Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus. Biochim Biophys Acta 1772:1158-66.HumanLiverCell death
Boushel 2007 Diabetologia2007Boushel RC, Gnaiger E, Schjerling P, Skovbro M, Kraunsoee R, Dela F (2007) Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790-6.HumanSkeletal muscleDiabetes
Obesity
Blakely 2006 Pediatr Res2006Blakely EL, Rennie KJ, Jones L, Elstner M, Chrzanowska-Lightowlers ZMA, White CB, Shield JPH, Pilz DT, Turnbull DM, Poulton J, Taylor RW (2006) Sporadic intragenic inversion of the mitochondrial DNA MTND1 gene causing fatal infantile lactic acidosis. Pediatr Res 59:440-4.HumanFibroblastMitochondrial disease
Safiulina 2006 Toxicol Sci2006Safiulina D, Peet N, Seppet E, Zharkovsky A, Kaasik A (2006) Dehydroepiandrosterone inhibits Complex I of the mitochondrial respiratory chain and is neurotoxic in vitro and in vivo at high concentrations. Toxicol Sci 93:348-56.RatNervous systemNeurodegenerative
Deschauer 2006 Mol Genet Metab2006Deschauer M, Gizatullina Z, Schulze A, Pritsch M, Knöppel C, Knape M, Zierz S, Gellerich FN (2006) Molecular and biochemical investigations in fumarase deficiency. Mol Genet Metab 88:146-52.HumanFibroblastInherited
Nukala 2006 J Neurosci Methods2006Nukala VN, Singh IN, Davis LM, Sullivan PG (2006) Cryopreservation of brain mitochondria: A novel methodology for functional studies. J Neurosci Methods 152:48-54.RatNervous systemCryopreservation
David 2005 J Biol Chem2005David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Muller WE, Eckert A, Götz J (2005) Proteomic and functional analysis reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem 280:23802-14.MouseNervous systemAging;senescence
Neurodegenerative
Anmann 2005 FEBS J2005Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet EK, Saks VA (2005) Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J 272:3145-61.RatHeart
Zacharovova 2005 Transplant Proc2005Zacharovova K, Berkova Z, Spacek T, Kriz J, Dovolilova E, Girman P, Koblas T, Jezek P, Saudek F (2005) In vitro assessment of pancreatic islet vitality by oxymetry. Transplant Proc 37:3454-6.RatIslet cell;pancreas;thymus
Toleikis 2005 Biosci Rep2005Toleikis A, Trumbeckaite S, Majiene D (2005) Cytochrome C effect on respiration of heart mitochondria: influence of various factors. Biosci Rep 25:387-97.Human
Rat
Rabbit		HeartIschemia-reperfusion
Chowdhury 2005 Biochem Biophys Res Comm2005Chowdhury SK, Gemin A, Singh G (2005) High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines. Biochem Biophys Res Comm 333:1139-45.HumanGenitalCancer
Vrbacky 2003 Physiol Res2003VrbackĂœ M, Krijt J, Drahota Z, MĕlkovĂĄ Z (2003) Inhibitory effects of Bcl-2 on mitochondrial respiration. Physiol Res 52:545-54.Human
Other mammals		Endothelial;epithelial;mesothelial cell
Other cell lines
HeLa		Cell death
Greco 2003 FASEB J2003Greco M, Villani G, Mazzucchelli F, Bresolin N, Papa S, Attardi G (2003) Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J 17:1706-8.FibroblastAging;senescence
Pecina 2003 Biochim Biophys Acta2003Pecina P, Capkova M, Chowdhury SK, Drahota Z, Dubot A, Vojtiskova A, Hansikova H, Houstekova H, Zeman J, Godinot C, Houstek J (2003) Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome. Biochim Biophys Acta 1639:53-63.HumanEndothelial;epithelial;mesothelial cell
Fibroblast		Inherited
Appaix 2003 Exp Physiol2003Appaix F, Kuznetsov AV, Usson Y, Kay L, Andrienko T, Olivares J, Kaambre T, Sikk P, Margreiter R, Saks V (2003) Possible role of cytoskeleton in intracellular arrangement and regulation of mitochondria. Exp Physiol 88:175-90.RatHeart
Skeletal muscle
Aguilaniu 2001 J Biol Chem2001Aguilaniu H, Gustafsson L, Rigoulet M, Nyström T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404.Saccharomyces cerevisiae
Fungi		Aging;senescence
Rasmussen 2001 Am J Physiol Endocrinol Metab2001Rasmussen UF, Rasmussen HN, Krustrup P, Quistorff B, Saltin B, Bangsbo J (2001) Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria. Am J Physiol Endocrinol Metab 280:E301-7.HumanSkeletal muscle
Appaix 2000 Biochim Biophys Acta2000Appaix F, Minatchy M-N, Riva-Lavieille C, Olivares J, Antonsson B, Saks VA (2000) Rapid spectrophotometric method for quantitation of cytochrome c release from isolated mitochondria or permeabilized cells revisited. Biochim Biophys Acta 1457:175-81.Heart
Du 1999 Free Radic Biol Med1999Du G, Willet K, Mouithys-Mickalad A, Sluse-Goffart CM, Droy-Lefaix M-T, Sluse FE (1999) EGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation. Free Radic Biol Med 27:596-604.RatLiverIschemia-reperfusion
Gnaiger 1998 Biochim Biophys Acta1998Gnaiger E, Lassnig B, Kuznetsov AV, Margreiter R (1998) Mitochondrial respiration in the low oxygen environment of the cell: Effect of ADP on oxygen kinetics. Biochim Biophys Acta 1365:249-54. https://doi.org/10.1016/S0005-2728(98)00076-0RatHeart
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Du 1998 Free Radic Biol Med1998Du G, Mouithys-Mickalad A, Sluse FE (1998) Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation. Free Radic Biol Med 25:1066-74.Ischemia-reperfusion
Villani 1997 Proc Natl Acad Sci U S A1997Villani G, Attardi G (1997) In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells. Proc Natl Acad Sci U S A 94:1166-71.HumanFibroblast
Devin 1997 Biochim Biophys Acta1997Devin A, Guerin B, Rigoulet M (1997) Control of oxidative phosphorylation in rat liver mitochondria: effect of ionic media. Biochim Biophys Acta 1319:293-300.RatLiver
Halangk 1997 Zentralbl Chir1997Halangk W, Matthias R, Nedelev B, Schild L, Meyer F, Schulz H-U, Lippert H (1997) BeeintrÀchtigung der Energiebereitstellung von Pankreasmitochondrien bei experimenteller akuter Pankreatitis. Zentralbl Chir 122:305-8.Mitochondrial disease
Halestrap 1986 Biochem J1986Halestrap AP, Dunlop JL (1986) Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J 239:559-65. https://doi.org/10.1042/bj2390559RatLiver
Boveris 1973 Biochem J1973Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-16.Rat
Birds		HeartOxidative stress;RONS
Grav 1970 Eur J Biochem1970Grav HJ, Pedersen JI, Christiansen EN (1970) Conditions in vitro which affect respiratory control and capacity for respiration-linked phosphorylation in brown adipose tissue mitochondria. Eur J Biochem 12:11-23.Guinea pigFat
Chance 1962 J Biol Chem1962Chance B, Hagihara B (1962) Activation and inhibition of succinate oxidation following adenosine diphosphate supplements to pigeon heart mitochondria. J Biol Chem 237:3540-5.BirdsHeart
Azzone 1961 J Biol Chem1961Azzone GF, Ernster L (1961) Demonstration of a requirement of high energy phosphate for the aerobic oxidation of succinate in liver mitochondria. J Biol Chem 236:1518-25.RatLiver
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