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• Wang Y 2019 J Biol Chem
  ...nal electrophoreses, nano-LC-MS/MS, immunogold EM, and stimulated emission depletion microscopy, we show that FAO enzymes physically interact with ETC supercomp ...its enoyl–CoA product with reduction of ETF. The protein complex promotes metabolite channeling for all these reactions. For steps 4 and 5, reduced ETF is relea
  5 KB (721 words) - 19:28, 10 September 2023
• MitoKit-CII
  ...release mechanism - the possibility of ATP requirements or other cellular depletion caused by prodrug metabolism. |mitopedia topic=Inhibitor, Substrate and metabolite
  5 KB (694 words) - 11:51, 17 August 2022
• Electron-transfer-pathway state
  ...hondria, permeabilized cells, permeabilized tissues, tissue homogenate) by depletion of endogenous substrates and addition to the mitochondrial respiration medi ...ndogenous. Long-term incubation under such conditions leads to progressive depletion of endogenous substrates.
  15 KB (1,913 words) - 19:27, 25 August 2023
• Gnaiger 2012 MitoPathways
  ...hosphorylation. III. The steady state. J Biol Chem 217:409-27. - Substrate depletion in isolated mitochondria is achieved in State 2: ADP is added to induce a t ...ddition of exogenous substrates. In such a study, the conventional initial depletion of endogenous substrates would be most important. (b) Maximal respiration r
  34 KB (4,820 words) - 04:08, 23 November 2021
• Gnaiger 2014 MitoPathways
  ...hosphorylation. III. The steady state. J Biol Chem 217:409-27. - Substrate depletion in isolated mitochondria is achieved in State 2: ADP is added to induce a t ...round are considered to be present at low concentrations due to metabolite depletion, whereas products with blue background are considered to accumulate in the
  51 KB (7,005 words) - 04:36, 19 July 2022
• Gnaiger 2020 BEC MitoPathways
  ...rations. These protocols ignored the importance of cataplerotic metabolite depletion in the tricarboxylic acid (TCA) cycle. ...eady state. - [[Chance 1955 J Biol Chem-III |»Bioblast link«]] - Substrate depletion in isolated mitochondria is achieved in State 2: ADP is added to induce a t
  89 KB (12,074 words) - 17:54, 6 May 2024
• Oroboros Ecosystem Agenda 2020 Archive
  ...f externally added uncouplers (i) in the absence of adenylates, (ii) after depletion of ADP, or (iii) after inhibition of ATP synthase or adenine nucleotide tra .../7b/Cronin_2018_Nature_O2k-brief.pdf|O2k-brief]] '''Cronin''' (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature - '''L
  126 KB (17,785 words) - 08:55, 13 August 2021

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