Substrates as electron donors: Difference between revisions

Latest revision as of 19:00, 7 May 2023

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Substrates as electron donors

Description

Substrates as electron donors are reduced fuel compounds S_red that are oxidized to an oxidized product P_ox during H⁺-linked electron transfer, S_red → P_ox + 2{H⁺ + e^-}. Mitochondrial respiration depends on a continuous flow of electron-supplying substrates across the mitochondrial membranes into the matrix space. Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.

Abbreviation: S_red

Reference: Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v3. https://doi.org/10.26124/mitofit:2023-0003.v3

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Substrate

» Substrate

» Product

» Substrates as electron donors

» Cellular substrates

» MitoPedia: Substrates and metabolites

» Substrate-uncoupler-inhibitor titration

Cofactor

» Cofactor

» Coenzyme, cosubstrate

» Nicotinamide adenine dinucleotide

» Coenzyme Q2

» Prosthetic group

» Flavin adenine dinucleotide

Referennces

» Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v6. https://doi.org/10.26124/mitofit:2023-0003.v6

MitoPedia topics: Substrate and metabolite

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 {{MitoPedia
-|description=Mitochondrial respiration depends on a continuous flow of electron-supplying substrates across the mitochondrial membranes into the matrix space.  Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.
+|abbr=''S''<sub>red</sub>
+|description='''[[Substrate]]s as electron donors''' are reduced fuel compounds ''S''<sub>red</sub> that are oxidized to an oxidized product ''P''<sub>ox</sub> during H<sup>+</sup>-linked electron transfer, ''S''<sub>red</sub> → ''P''<sub>ox</sub> + 2{H<sup>+</sup> + e<sup>-</sup>}. Mitochondrial respiration depends on a continuous flow of electron-supplying substrates across the mitochondrial membranes into the matrix space. Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.
+|info=Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v3. https://doi.org/10.26124/mitofit:2023-0003.v3
 }}
-{{MitoPedia concepts}}
+{{Template:Keywords: Substrates and cofactors}}
-{{MitoPedia methods
-|mitopedia method=Respirometry
-}}
-{{MitoPedia O2k and high-resolution respirometry}}
 {{MitoPedia topics
 |mitopedia topic=Substrate and metabolite
 }}