Template:O2k-PublicationAlert2022

Mitochondria and Cell Research - the Oroboros Ecosystem

» Listed in Oroboros Ecosystem Agenda

Sep 2022

• Sep-29 Th - World Heart Day

Respiration compromised in brain and heart tissue homogenate after cardiac arrest and ischemia/reperfusion injury Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. -»Bioblast link« from the O2k-Network »US VA Richmond Mangino MJ«

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• Sep-28 We

“Calcium-induced [mtPTP] is suppressed by exogenous additions of ADP compared to ADP combined with a hexokinase 2-deoxyglucose system of recycling ATP to ADP.” Bellissimo CA, Sondergaard S, Hughes MC, Ramos SV, Larsen S, Perry CGR (2022) The influence of adenylate cycling on mitochondrial calcium-induced permeability transition pore in permeabilized skeletal muscle fibres. https://doi.org/10.26124/mitofit:2022-0026 from the O2k-Network »CA Toronto Perry CG«, »DK Copenhagen Larsen S«

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• Sep-23 Fr

Investigating the cause of late-onset SLC25A26-related mitochondrial disease Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A (2022) Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. »Bioblast link« from the O2k-Network »BE Leuven Vermeersch P«

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• Sep-21 We

"By tracing the carbon flow of the nutrients glucose and glutamine in cells derived from patients with different genetically defined causes of primary mitochondrial diseases (PMD), we identified several key metabolic changes supporting the major importance of an NAD+/NADH imbalance in PMD." Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B (2022) Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. »Bioblast link« from the O2k-Network »BE Leuven Vermeersch P«

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• Sep-20 Tu

Bioenerg Commun 2022.4: A review on the current landscape of mitochondrial disease drug development Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004 from the O2k-Network »SE Lund Elmer E«

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• Sep-15 Th - World Lymphoma Awareness Day

OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. »Bioblast link« from the O2k-Network »DE Frankfurt Droese S«, »DE Frankfurt Wittig I« and »NL Nijmegen Brandt U«

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• Sep-14 We

Bioenerg Commun 2022.9:A publication with video presentation from Bioblast 2022: BEC Inaugural Conference Posch W, Dichtl S, Zaderer V, Lass-Flörl C, Wilflingseder D (2022) How to optimize respiratory models for SARS-CoV-2 research. https://doi.org/10.26124/bec:2022-0009

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• Sep-12 Mo

From the MitoKIN project - preprint to publication: Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917 from the O2k-Network »AT Innsbruck Oroboros«

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• Sep-05 Mo - Prostate Cancer Awareness Month

“Mitochondria of the malignant prostate cells have a higher affinity for succinate and this metabolite supports mitochondrial physiology through the induction of expression and activities of mitochondrial complexes” Bastos Sant'Anna Silva AC, Perez-Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. Cancers 13:1727.»Bioblast link« from the O2k-Network »AT Innsbruck Oroboros« and »FR Bordeaux Rossignol R«

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• Sep- 01 Th - Leukemia and Lymphoma Awareness Month

Metformin-mediated reduction of mitochondrial activity contributes to decreased cell viability in myeloproliferative neoplasms cells Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. »Bioblast link« from the O2k-Network »BR Ribeirao Preto Alberici LC«

Aug 2022

• Aug-16 Tu

Exploring photosynthesis and dark respiration in the microalgae Chlamydomonas reinhardtii Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Prep 2021.5. doi:10.26124/mitofit:2021-0005

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• Aug-09 Tu

Bioenerg Commun 2022.8: Quality Control Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. https://doi.org/10.26124/bec:2022-0008 from the O2k-Network »AT Innsbruck Oroboros«

Jul 2022

• Jul-28 Th - World Hepatitis Day

Cells expressing hepatitis B protein X showed increased ROUTINE, LEAK and ET capacity compared to control cells. Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. »Bioblast link«

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• Jul- 14 Th

A preprint from Bioblast 2022: BEC Inaugural Conference - Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025

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• Jul- 11 Mo

A publication from Bioblast 2022: BEC Inaugural Conference - Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/bec:2022-0006

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• Jul- 06 We

A publication from Bioblast 2022: BEC Inaugural Conference - Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004

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• Jul- 05 Tu

A publication from Bioblast 2022: BEC Inaugural Conference - Abed Rabbo M, Stiban J (2022) NUBPL: a mitochondrial Complex I deficiency disorder. https://doi.org/10.26124/bec:2022-0003

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• Jul- 04 Mo

A publication from Bioblast 2022: BEC Inaugural Conference - Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2021) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. https://doi.org/10.26124/bec:2022-0002

Jun 2022

• Jun- 22 We

Co-write a BEC editorial Join the discussion on Jun 30 - » BEC is the future«

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• Jun- 18 Sa

BEC 2022.1. - The book of abstracts is online Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001 - »Bioenerg Commun 2022.1.«

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• Jun- 06 Mo

Scientific journals apply yesterday's concepts in the various formats of references with bewildering abbreviations of journals, volumes, issues, page numbers. We can do today's job much better using the BEC https-format — in line with DORA. - »References in BEC https-format — in MitoPedia: BEC

May 2022

*May- 19 Th

"Instrumental QC is a cornerstone for experimental reproducibility." Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. MitoFit Preprints 2022.18. https://doi.org/10.26124/mitofit:2022-0018.v2 from the O2k-Network »AT Innsbruck Oroboros«

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• May- 04 We

"More systematic profiling of mitochondrial bioenergetic states in the presence and absence of lead molecules or kinase drugs could become an asset for anticipating non-desired off-target drug features." Torres-Quesada Omar, Strich Sophie, Stefan Eduard (2022) Kinase perturbations redirect mitochondrial function. MitoFit Prep 2022.11. https://doi.org/10.26124/mitofit:2022-0011 from the O2k-Network »AT Innsbruck Oroboros«

Apr 2022

• Apr- 25 Mo

"Proline catabolism through ProDH generates sufficient CIII and CIV proton pumping, supporting ATP production by F1FO-ATPase even when CI is inhibited" Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. MitoFit Preprints 2022.1.v3. https://doi.org/10.26124/mitofit:2022-0001.v3 from the O2k-Network »AT Innsbruck Oroboros« and »HU Budapest Chinopoulos C«

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• Apr- 19 Tu

"The physiological Human Plasma-Like Media alters proliferative behavior, mitochondrial bioenergetic states and kinase drug sensitivity of cancer cells when compared to classic cell culture media." Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. MitoFit Preprints 2022.8. https://doi.org/10.26124/mitofit:2022-0008 from the O2k-Network »AT Innsbruck Oroboros«

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• Apr- 11 Mo - World Parkinson´s Disease Day

Reviewing cellular models to decipher the mechanisms of mitochondrial dysfunction in Parkinson's disease Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002 from the O2k-Networks »RS Belgrade Lalic NM«, »UK Nottingham Chakrabarti L« and »UK Leicester Moisoi N«

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• Apr- 04 Mo - April is Parkinson's Awareness Month

"Early stage α-synuclein pathology does not influence mitochondrial respiration in the striatum and amygdala [of mice]" Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. »Bioblast link« from the O2k-Network »CH Lausanne Place N« and »CH Lausanne Sandi C«

Mar 2022

• Mar- 15 Tu

"MDH2 is a metabolic switch rewiring [electron transfer system] and TCA fuelling" Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532. »Bioblast link« from the O2k-Network »FR Bordeaux Mourier A«

Feb 2022

• Feb- 10 Th

Alterations in molecular and cellular pathways contribute to skeletal muscle-related symptoms in Covid-19 Soares MN, Eggelbusch M, Naddaf E, Gerrits KHL, van der Schaaf M, van den Borst B, Wiersinga WJ, van Vugt M, Weijs PJM, Murray AJ, Wüst RCI (2022) Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19. J Cachexia Sarcopenia Muscle. »Bioblast link« from the O2k-Network »NL Amsterdam Wuest RC« and »UK Cambridge Murray AJ«

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• Feb- 09 We

'The scientific literature is exploding in quantity even as it stands still in literary quality.' - Wells WA (2004) Me write pretty one day: how to write a good scientific paper. J Cell Biol 165:757-8. »Bioblast link« Sequential editions provide an opportunity to improve quality while preventing explosions on quantity. - Gnaiger (2021) Editorial Bioenerg Commun

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• Feb- 08 Tu

Now accepting living communications for Bioblast 2022 - BEC Inaugural Issue -»More details«

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• Feb- 04 Fr

Acute sarcoplasmic reticulum calcium leak increases mitochondrial respiration after simulated sprint interval training Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link« from the O2k-Network »CH Lausanne Place N« and »ES Barcelona Garcia-Roves PM«

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• Feb- 01 Tu

From preprint to journal publication: Vernerova A, Garcia-Souza LF, Soucek O, Kostal M, Rehacek V, Krcmova LK, Gnaiger E, Sobotka O (2021) Mitochondrial respiration of platelets: comparison of isolation methods. Biomedicines 9:1859. doi.org/10.3390/biomedicines9121859 from the O2k-Network »CZ Hradec Kralove Cervinkova Z« and »AT Innsbruck Oroboros«

Jan 2022

• Jan- 28 Fr

Oroboros Ecosystem Agenda and Bioblast alert consider to refrain from propagating scientific publications in paywall and predatory journals. A definition is required of paywall and predatory journals. Paywall and predatory journals are not the future of scientific communication.

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• Jan- 25 Tu

From preprint to journal publication: Fischer C, Volani C, Komlódi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. Antioxidants 10:1818. doi.org/10.3390/antiox10111818 from the O2k-Network »AT Innsbruck Oroboros«

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• Jan- 21 Fr

'The burden of responsibilities for an urgent change of the academic publishing ecosystem and scientific communication culture must be shared between the shoulders of individual scientists, the backbone of scientific institutions, and the neurology of governmental regulations and funding agencies.' - Gnaiger (2021) Editorial Bioenerg Commun

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• Jan- 19 We

Elsevier bought Pergamon Press in 1991 for £440m (£919m today) from Robert Maxwell. R Maxwell may be known in relation to financial scandals and to his daughter Ghislaine Maxwell who was convicted on 2021-12-29 linked to several federal crimes including her involvement in a sex-trafficking ring with Jeffrey Epstein, to who's former friends belonged British Prince Andrew, former Prime Minister Tony Blair, or ex-US-presidents Bill Clinton and Donald Trump. Due to paywall journals, Open Access in science remains an unfulfilled dream. - Gnaiger (2021) Editorial BEC Living Communication (2022-01-04)

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• Jan- 18 Tu

The process of Lewy body formation in Parkinson's Disease induces mitochondrial deficits Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. Mahul-Mellier 2020 Proc Natl Acad Sci U S A from the O2k-Network »CH Lausanne Place N«

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• Jan- 17 Mo

'Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year. ' - Gnaiger (2021) Editorial Bioenerg Commun

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