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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Seite 2018 Sci Rep	2018	Seite S, Mourier A, Camougrand N, Salin B, Figueiredo-Silva AC, Fontagne-Dicharry S, Panserat S, Seiliez I (2018) Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss). Sci Rep 8:10151.		N S CIV NS ROX	Homogenate	Fishes	Liver
Budai 2018 Br J Surg	2018	Budai A, Horváth G, Tretter L, Radák Z, Koltai E, Bori Z, Torma F, Lukáts Á, Röhlich P, Szijártó A, Fülöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31.	OXPHOS	N S	Isolated mitochondria	Rat	Liver
Friederich 2018 Nat Commun	2018	Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNA^Gln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human Fungi	Fibroblast
Reguis Yadao 2018 Thesis	2018	Reguis Yadao DR (2018) Smooth muscle cell mitochondrial respiration – effects of aerobic training and type I diabetes. Master's Thesis 71.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Other cell lines
Isohanni 2018 Neurogenetics	2018	Isohanni P, Carroll CJ, Jackson CB, Pohjanpelto M, Lönnqvist T, Suomalainen A (2018) Defective mitochondrial ATPase due to rare mtDNA m.8969G>A mutation-causing lactic acidosis, intellectual disability, and poor growth. Neurogenetics 19:49-53.	OXPHOS ET	N S CIV NS	Permeabilized cells	Human	Skeletal muscle Blood cells Fibroblast
Cree-Green 2018 Diabetes	2018	Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, Mcclatchey PM, Bauer TA, Regensteiner JG, Reusch JEB (2018) Supplemental oxygen improves in-vivo mitochondrial oxidative phosphorylation flux in sedentary obese adults with type 2 diabetes. Diabetes 67:1369-79.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Jelenik 2018 Mol Metab	2018	Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Keller 2018 Oxid Med Cell Longev	2018	Keller AC, Knaub LA, Scalzo RL, Hull SE, Johnston AE, Walker LA, Reusch JEB (2018) Sepiapterin improves vascular reactivity and insulin-stimulated glucose in wistar rats. Oxid Med Cell Longev 2018:7363485.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Rat	Endothelial;epithelial;mesothelial cell
Thompson 2018 EMBO Mol Med	2018	Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060.	LEAK OXPHOS	N CIV ROX Gp Other combinations	Homogenate	Drosophila
Doerrier 2018 Methods Mol Biol	2018	Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS Other combinations ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells	Human Mouse Rat Saccharomyces cerevisiae	Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet
Chung 2018 Integr Comp Biol	2018	Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM (2018) Mitochondria, temperature, and the pace of life. Integr Comp Biol 58:578-90.	OXPHOS	N	Permeabilized tissue Isolated mitochondria	Fishes	Heart Nervous system Liver
Johnson 2018 J Mol Cell Cardiol	2018	Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K (2018) Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. J Mol Cell Cardiol 121:94-102.	OXPHOS ET	F N S NS	Isolated mitochondria	Mouse	Heart Skeletal muscle
Merz 2018 Intensive Care Med Exp	2018	Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O (2018) Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp 6:43.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Pig	Kidney
Fuhrmann 2018 Cell Mol Life Sci	2018	Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67.	LEAK ROUTINE OXPHOS ET	N S ROX	Isolated mitochondria Intact cells	Human
Dogan 2018 Cell Metab	2018	Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77.	LEAK OXPHOS	N S CIV ROX	Isolated mitochondria	Mouse	Skeletal muscle
Sprenger 2018 EMBO Mol Med	2018	Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2018) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11:e9288.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Nervous system
Jang 2018 Intensive Care Med Exp	2018	Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	Blood cells
Jang 2018 J Med Toxicol	2018	Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51.	LEAK ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Intact cells Permeabilized cells	Human	Blood cells
Zhang 2018 J Gerontol A Biol Sci Med Sci	2018	Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22.	LEAK OXPHOS	F N NS		Mouse	Skeletal muscle
Weber 2018 Int J Mol Sci	2018	Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129.	ROUTINE OXPHOS ET	F N S NS Other combinations ROX	Intact cells Permeabilized cells	Human	Genital
Champigny 2018 Mar Drugs	2018	Champigny CM, Cormier RPJ, Simard CJ, St-Coeur PD, Fortin S, Pichaud N (2018) Omega-3 monoacylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized tissue	Drosophila
Simard 2018 J Vis Exp	2018	Simard CJ, Pelletier G, Boudreau LH, Hebert-Chatelain E, Pichaud N (2018) Measurement of mitochondrial oxygen consumption in permeabilized fibers of Drosophila using minimal amounts of tissue. J Vis Exp 134.	LEAK OXPHOS	N Gp CIV NS ROX	Permeabilized tissue	Drosophila
Wefers 2018 Proc Natl Acad Sci U S A	2018	Wefers J, van Moorsel D, Hansen J, Connell NJ, Havekes B, Hoeks J, van Marken Lichtenbelt WD, Duez H, Phielix E, Kalsbeek A, Boekschoten MV, Hooiveld GJ, Hesselink MKC, Kersten S, Staels B, Scheer FAJL, Schrauwen P (2018) Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proc Natl Acad Sci U S A 115:7789-94.	OXPHOS ET	F N	Intact cells	Human	Skeletal muscle
Trewin 2018 Am J Physiol Regul Integr Comp Physiol	2018	Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H₂O₂ release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Souza 2018 Sci Rep	2018	Souza RWA, Alves CRR, Medeiros A, Rolim N, Silva GJJ, Moreira JBN, Alves MN, Wohlwend M, Gebriel M, Hagen L, Sharma A, Koch LG, Britton SL, Slupphaug G, Wisløff U, Brum PC (2018) Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Sci Rep 8:17772.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Rat	Heart Skeletal muscle
Docherty 2018 Atherosclerosis	2018	Docherty CK, Carswell A, Friel E, Mercer JR (2018) Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis 268:1-11.	OXPHOS	N CIV NS ROX	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Logan 2018 Mol Metab	2018	Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55.	LEAK OXPHOS	N S NS	Isolated mitochondria	Mouse	Nervous system
Ramil 2018 Thesis	2018	Ramil LR, Gulbinas A, Cesna V (2018) “HIPEC” hyperthermic intraperitoneal chemotherapy. Evaluation of intraperitoneal free cancer cells. Master's Thesis.	OXPHOS LEAK	N S	Isolated mitochondria	Human	Endothelial;epithelial;mesothelial cell
Hedges 2018 FASEB J	2018	Hedges CP, Bishop DJ, Hickey AJR (2018) Voluntary wheel running prevents the acidosis-induced decrease in skeletal muscle mitochondrial reactive oxygen species emission. FASEB J 33:4996-5004.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Cooper 2018 Exp Physiol	2018	Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12.	OXPHOS ET LEAK	F N NS	Permeabilized tissue	Mouse	Nervous system
Rocha 2018 J Physiol Biochem	2018	Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72.	LEAK OXPHOS ET	F N CIV NS ROX	Permeabilized tissue	Mouse	Heart
Zhuang 2018 Thesis	2018	Zhuang Y (2018) Potential application of alternative oxidase (AOX) in neurodegenerative diseases. Master's Thesis p71.	OXPHOS	N S CIV ROX	Isolated mitochondria	Mouse	Nervous system
Remor 2018 Mol Neurobiol	2018	Remor AP, da Silva RA, de Matos FJ, Glaser V, de Paula Martins R, Ghisoni K, da Luz Scheffer D, Andia DC, Portinho D, de Souza AP, de Oliveira PA, Prediger RD, Torres AI, Linhares RMM, Walz R, Ronsoni MF, Hohl A, Rafacho A, Aguiar AS Jr, De Paul AL, Latini A (2018) Chronic metabolic derangement-induced cognitive deficits and neurotoxicity are associated with REST inactivation. Mol Neurobiol 56:1539-57.	LEAK OXPHOS	N	Intact cells	Rat	Nervous system
Stepanova 2018 J Cereb Blood Flow Metab	2018	Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab 39:1790-802.	OXPHOS ET LEAK	N S ROX	Isolated mitochondria	Rat	Nervous system
Fisher-Wellman 2018 Cell Rep	2018	Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606.	LEAK OXPHOS	F N S	Isolated mitochondria	Mouse	Heart Skeletal muscle
Setz 2018 Hear Res	2018	Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65.	OXPHOS ET	F N S NS ROX	Permeabilized cells	Mouse	Other cell lines
Zhang 2018 J Mol Cell Cardiol	2018	Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser⁷²⁷. J Mol Cell Cardiol 118:169-82.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Isolated mitochondria	Mouse	Heart
Chou 2018 Int J Cardiol	2018	Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20.	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Intact cells Permeabilized cells	Human	Platelet Blood cells
Tyagi 2018 Sci Rep	2018	Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S (2018) SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep 8:17547.	LEAK OXPHOS ET	N NS	Homogenate	Mouse	Nervous system
Augustynek 2018 Int J Mol Sci	2018	Augustynek B, Koprowski P, Rotko D, Kunz WS, Szewczyk A, Kulawiak B (2018) Mitochondrial BK channel openers CGS7181 and CGS7184 exhibit cytotoxic properties. Int J Mol Sci 19. pii: E353.	OXPHOS	N	Isolated mitochondria	Rat	Nervous system
Monaco 2018b Diabetologia	2018	Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR (2018) Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes. Diabetologia 61:1411-23.	OXPHOS	N S Gp NS ROX	Permeabilized tissue	Human	Skeletal muscle
Uribe-Alvarez 2018 Microbiologyopen	2018	Uribe-Alvarez C, Chiquete-Félix N, Morales-García L, Bohórquez-Hernández A, Delgado-Buenrostro NL, Vaca L, Peña A, Uribe-Carvajal S (2018) Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism. Microbiologyopen 8:e00675.	OXPHOS ET	CIV ROX N NS	Isolated mitochondria	Saccharomyces cerevisiae
Campbell 2018 Free Radic Biol Med	2018	Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
D'Souza 2018 J Lipid Res	2018	D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17.	LEAK OXPHOS	F N S ROX	Permeabilized tissue	Mouse	Skeletal muscle
Bytautiene 2018 J Dev Orig Health Dis	2018	Bytautiene Prewit E, Porter C, La Rosa M, Bhattarai N, Yin H, Gamble P, Kechichian T, Sidossis LS (2018) Adipose tissue uncoupling protein 1 levels and function are increased in a mouse model of developmental obesity induced by maternal exposure to high-fat diet. J Dev Orig Health Dis 9:401-8.	LEAK	F N	Permeabilized tissue	Mouse	Fat
Brunetta 2018 Exp Physiol	2018	Brunetta HS, de Paula GC, de Oliveira J, Martins EL, Dos Santos GJ, Filho AG, Rafacho A, de Bem AF, Nunes EA (2018) Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice. Exp Physiol 104:306-21.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Friederich-Persson 2018 Acta Physiol (Oxf)	2018	Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Kidney
Scott 2018 Integr Comp Biol	2018	Scott GR, Guo KH, Dawson NJ (2018) The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol 58:506-18. https://doi.org/10.1093/icb/icy056	OXPHOS ET	N S CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Heart Skeletal muscle
Mayer 2018 Endocrinology	2018	Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26.	OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver
Takahashi 2018 Sci Rep	2018	Takahashi K, Miura Y, Ohsawa I, Shirasawa T, Takahashi M (2018) In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep 8:15585.	OXPHOS	N	Isolated mitochondria	Mouse	Nervous system
Giordano 2018 Am J Respir Cell Mol Biol	2018	Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M (2018) Alternative oxidase attenuates cigarette smoke-induced lung dysfunction and tissue damage. Am J Respir Cell Mol Biol 60:515-22.	OXPHOS	N S CIV ROX	Permeabilized cells	Mouse	Fibroblast
Christen 2018 Free Radic Biol Med	2018	Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Fishes	Heart
Scheiber 2018 J Cardiovasc Transl Res	2018	Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Heart
Cruz 2018 Chem Biol Interact	2018	Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Drosophila
Monzio Compagnoni 2018 Biochim Biophys Acta Mol Basis Dis	2018	Monzio Compagnoni G, Kleiner G, Bordoni A, Fortunato F, Ronchi D, Salani S, Guida M, Corti C, Pichler I, Bergamini C, Fato R, Pellecchia MT, Vallelunga A, Del Sorbo F, Elia A, Reale C, Garavaglia B, Mora G, Albanese A, Cogiamanian F, Ardolino G, Bresolin N, Corti S, Comi GP, Quinzii CM, Di Fonzo A (2018) Mitochondrial dysfunction in fibroblasts of multiple system atrophy. Biochim Biophys Acta Mol Basis Dis 1864:3588-97.	OXPHOS ET ROUTINE	N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Monaco 2018 Diabetologia	2018	Monaco CMF, Proudfoot R, Miotto PM, Herbst EAF, MacPherson REK, Holloway GP (2018) α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats. Diabetologia 61:433-44.		F N	Permeabilized tissue	Rat	Skeletal muscle Fat
Woodman 2018 FASEB J	2018	Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Rat	Liver Kidney
Cardinale 2018 Thesis	2018	Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99.	LEAK OXPHOS	F N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Sahl 2018 Anal Biochem	2018	Sahl RE, Morville T, Kraunsøe R, Dela F, Helge JW, Larsen S (2018) Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. Anal Biochem 556:119-24.	OXPHOS ET	N NS	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse Saccharomyces cerevisiae	Skeletal muscle
Dandanell 2018 Scand J Med Sci Sports	2018	Dandanell S, Meinild-Lundby AK, Andersen AB, Lang PF, Oberholzer L, Keiser S, Robach P, Larsen S, Rønnestad BR, Lundby C (2018) Determinants of maximal whole-body fat oxidation in elite cross-country skiers: role of skeletal muscle mitochondria. Scand J Med Sci Sports 28:2494-504.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Gorgey 2018 Eur J Appl Physiol	2018	Gorgey AS, Witt O, O'Brien L, Cardozo C, Chen Q, Lesnefsky EJ, Graham ZA (2018) Mitochondrial health and muscle plasticity after spinal cord injury. Eur J Appl Physiol 119:315-31.	OXPHOS LEAK	N S CIV NS	Permeabilized tissue	Human	Skeletal muscle
Warnsmann 2018 Mech Ageing Dev	2018	Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58.	LEAK OXPHOS ET	N	Isolated mitochondria	Fungi
Tillmans 2018 Thesis	2018	Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92.	LEAK ROUTINE ET	N S NS ROX	Intact cells Permeabilized cells	Human	Other cell lines Lymphocyte
Rossignoli 2018 J Nutr Biochem	2018	Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23.	LEAK ET OXPHOS	N S	Permeabilized cells Isolated mitochondria	Mouse	Skeletal muscle Nervous system Liver Fat
Lee 2018 Neurol Genet	2018	Lee RG, Sedghi M, Salari M, Shearwood AJ, Stentenbach M, Kariminejad A, Goullee H, Rackham O, Laing NG, Tajsharghi H, Filipovska A (2018) Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction. Neurol Genet 4:e276.	LEAK OXPHOS ET	N S CIV NS	Permeabilized cells	Human	Fibroblast
Bricambert 2018 Nat Commun	2018	Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092.	LEAK OXPHOS ET	N S	Homogenate	Mouse	Liver
Monaco 2018 Am J Physiol Regul Integr Comp Physiol	2018	Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204.	LEAK OXPHOS	N NS	Permeabilized tissue Isolated mitochondria	Rat	Heart
Laouafa 2018 Adv Exp Med Biol	2018	Laouafa S, Roussel D, Marcouiller F, Soliz J, Bairam A, Joseph V (2018) Role of estradiol receptor beta (ERβ) on arterial pressure, respiratory chemoreflex and mitochondrial function in young and aged female mice. Adv Exp Med Biol 1071:115-27.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Galvan 2018 Biochim Biophys Acta	2018	Galván AE, Chalón MC, Schurig-Briccio LA, Salomón RA, Minahk CJ, Gennis RB, Bellomio A (2018) Cytochromes bd-I and bo3 are essential for the bactericidal effect of microcin J25 on Escherichia coli cells. Biochim Biophys Acta 1859:110-8.		N		Eubacteria
Bouwkamp 2018 Neurol Genet	2018	Bouwkamp CG, Afawi Z, Fattal-Valevski A, Krabbendam IE, Rivetti S, Masalha R, Quadri M, Breedveld GJ, Mandel H, Tailakh MA, Beverloo HB, Stevanin G, Brice A, van IJcken WFJ, Vernooij MW, Dolga AM, de Vrij FMS, Bonifati V, Kushner SA (2018) ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia. Neurol Genet 4:e223.	OXPHOS ET	N	Isolated mitochondria	Human
Pileggi 2018 Free Radic Biol Med	2018	Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H₂O₂ emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Lander 2018 J Biol Chem	2018	Lander N, Chiurillo MA, Bertolini MS, Storey M, Vercesi AE, Docampo R (2018) Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi. J Biol Chem 293:17402-17.	LEAK OXPHOS ET	N S	Permeabilized cells	Protists
Lobo-Jarne 2018 Cell Rep	2018	Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized cells	Human	HEK Other cell lines
Zhang 2018 Cardiovasc Diabetol	2018	Zhang X, Zhang Z, Yang Y, Suo Y, Liu R, Qiu J, Zhao Y, Jiang N, Liu C, Tse G, Li G, Liu T (2018) Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits. Cardiovasc Diabetol 17:160.	OXPHOS LEAK	N	Isolated mitochondria	Rabbit	Heart
Hoffmann 2018 Sci Rep	2018	Hoffmann C, Höckele S, Kappler L, Hrabĕ de Angelis M, Häring HU, Weigert C (2018) The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells. Sci Rep 8:737.	OXPHOS ET	F N S NS ROX	Permeabilized cells	Human	Skeletal muscle
Bradley 2018 Biochim Biophys Acta	2018	Bradley RM, Bloemberg D, Aristizabal Henao JJ, Hashemi A, Mitchell AS, Fajardo VA, Bellissimo C, Mardian EB, Bombardier E, Paré MF, Moes KA, Stark KD, Tupling AR, Quadrilatero J, Duncan RE (2018) Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fiber type in extensor digitorum longus muscle. Biochim Biophys Acta 1863:700-11.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Mouse	Skeletal muscle
Klepinin 2018 J Bioenerg Biomembr	2018	Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Mouse	Heart Neuroblastoma
Nielsen 2018 Neurosci Lett	2018	Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB (2018) Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue. Neurosci Lett 690:1-5.	LEAK OXPHOS ET	N NS ROX S	Homogenate	Rat	Nervous system
Lu 2018 Cell Discov	2018	Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58.	OXPHOS ET	F N ROX	Isolated mitochondria	Rat	Skeletal muscle Liver
Astrakhanova 2018 Sovrem Tekhnologii Med	2018	Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94.	OXPHOS LEAK	N S	Isolated mitochondria	Mouse	Nervous system
Bhaskaran 2018 EMBO Rep	2018	Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009.	LEAK OXPHOS	N S NS		Mouse	Fat
Kong 2018 Proteomics	2018	Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Trumbeckaite 2018 J Bioenerg Biomembr	2018	Trumbeckaite S, Cesna V, Jasukaitiene A, Baniene R, Gulbinas A (2018) Different mitochondrial response to cisplatin and hyperthermia treatment in human AGS, Caco-2 and T3M4 cancer cell lines. J Bioenerg Biomembr 50:329-38.	OXPHOS	N S	Permeabilized cells	Human	Other cell lines
Leo 2018 Conserv Physiol	2018	Leo E, Dahlke FT, Storch D, Poertner HO, Mark FC (2018) Impact of Ocean Acidification and Warming on the bioenergetics of developing eggs of Atlantic herring Clupea harengus. Conserv Physiol 6:coy050.	ET	N S	Homogenate	Fishes
Hedges 2018 J Appl Physiol (1985)	2018	Hedges CP, Woodhead JST, Wang HW, Mitchell CJ, Cameron-Smith D, Hickey AJR, Merry TL (2018) Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men. J Appl Physiol (1985) 126:454-61.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue Intact cells	Human	Skeletal muscle Blood cells
Meinild Lundby 2018 Acta Physiol (Oxf)	2018	Meinild Lundby AK, Jacobs RA, Gehrig S, de Leur J, Hauser M, Bonne TC, Flück D, Dandanell S, Kirk N, Kaech A, Ziegler U, Larsen S, Lundby C (2018) Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. Acta Physiol (Oxf) 222, e12905.	OXPHOS LEAK ET	NS F N CIV	Permeabilized tissue	Human	Skeletal muscle
Burtscher 2018 Front Mol Neurosci	2018	Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Arnoux 2018 Elife	2018	Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. Elife 7:e38744.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Weisz 2018 Hum Mol Genet	2018	Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106.	OXPHOS ET LEAK	N S NS ROX	Isolated mitochondria	Drosophila	Skeletal muscle
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol	2018	Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Mouse Rat	Skeletal muscle
Braz-Mota 2018 Sci Total Environ	2018	Braz-Mota S, Campos DF, MacCormack TJ, Duarte RM, Val AL, Almeida-Val VMF (2018) Mechanisms of toxic action of copper and copper nanoparticles in two Amazon fish species: Dwarf cichlid (Apistogramma agassizii) and cardinal tetra (Paracheirodon axelrodi). Sci Total Environ 630:1168-80.	LEAK OXPHOS ET	N NS ROX		Fishes	Lung;gill
Kriel 2018 Sci Rep	2018	Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348.	LEAK OXPHOS ET ROUTINE	N ROX	Permeabilized cells	Human	Nervous system Other cell lines
Cardinale 2018 Front Physiol	2018	Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133.	OXPHOS	F N NS	Isolated mitochondria	Human	Skeletal muscle
Tripodi 2018 Biochim Biophys Acta Mol Cell Res	2018	Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13.	OXPHOS LEAK	N S	Isolated mitochondria	Saccharomyces cerevisiae
Cecatto 2018 FEBS J	2018	Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca²⁺ homeostasis in the heart. FEBS J 285:1437-55.	LEAK OXPHOS ET	N S	Permeabilized cells Permeabilized tissue Isolated mitochondria	Rat	Heart Other cell lines
Lund 2018 Acta Physiol (Oxf)	2018	Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, Støckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Ravera 2018 Biol Cell	2018	Ravera S, Signorello MG, Bartolucci M, Ferrando S, Manni L, Caicci F, Calzia D, Panfoli I, Morelli A, Leoncini G (2018) Extramitochondrial energy production in platelets. Biol Cell 110:97-108.		N S	Permeabilized cells	Human	Blood cells Platelet
Van der Pluijm 2018 Cardiovasc Res	2018	van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93.	OXPHOS	N S NS ROX	Homogenate	Mouse	Skeletal muscle
Park 2018 J Clin Invest	2018	Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711.	OXPHOS ET LEAK	F N S	Permeabilized tissue	Mouse	Fat
Song 2018 Proc Natl Acad Sci U S A	2018	Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G (2018) Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes. Proc Natl Acad Sci U S A 115:1576-81.	LEAK OXPHOS ET	N S NS	Intact cells	Rat	Heart
Komlodi 2018 Methods Mol Biol	2018	Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Permeabilized tissue	Human Mouse	Skeletal muscle HEK
Belosludtsev 2018 Biochim Biophys Acta	2018	Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97.	OXPHOS	N S NS	Isolated mitochondria	Rat	Liver
Reutzel 2018 Oxid Med Cell Longev	2018	Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Koit 2018 US Patent	2018	Koit A, Kaambre T (2018) Method for selecting patients responsive for cancer treatments. US Patent US20180017547A1.	OXPHOS	F N NS	Permeabilized cells	Human
Temelie 2018 Oxid Med Cell Longev	2018	Temelie M, Savu DI, Moisoi N (2018) Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1. Oxid Med Cell Longev 1391387.	OXPHOS ET	N NS	Permeabilized cells	Human Mouse	Nervous system Other cell lines Fibroblast
Eimre 2018 Oxid Med Cell Longev	2018	Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313.	OXPHOS LEAK	N S CIV ROX	Permeabilized tissue	Mouse	Skeletal muscle
Shen 2018 Biosci Rep	2018	Shen NY, Ng SY, Toepp SL, Ljubicic V (2018) Protein arginine methyltransferase expression and activity during myogenesis. Biosci Rep 38. pii: BSR20171533.	OXPHOS	N NS	Permeabilized cells	Mouse	Skeletal muscle
Corrochano 2018 Hum Mol Genet	2018	Corrochano S, Blanco G, Williams D, Wettstein J, Simon M, Kumar S, Moir L, Agnew T, Stewart M, Landman A, Kotiadis VN, Duchen MR, Wackerhage H, Rubinsztein DC, Brown SDM, Acevedo-Arozena A (2018) A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet 27:1723-31.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Baaten 2018 Haematologica	2018	Baaten CCFMJ, Moenen FCJI, Henskens YMC, Swieringa F, Wetzels RJH, van Oerle R, Heijnen HFG, Ten Cate H, Holloway GP, Beckers EAM, Heemskerk JWM, van der Meijden PEJ (2018) Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica 103:1557-67.	OXPHOS	N NS	Intact cells	Human	Blood cells Platelet
Briones-Herrera 2018 Food Chem Toxicol	2018	Briones-Herrera A, Avila-Rojas SH, Aparicio-Trejo OE, Cristóbal M, León-Contreras JC, Hernández-Pando R, Pinzón E, Pedraza-Chaverri J, Sánchez-Lozada LG, Tapia E (2018) Sulforaphane prevents maleic acid-induced nephropathy by modulating renal hemodynamics, mitochondrial bioenergetics and oxidative stress. Food Chem Toxicol 115:185-97.	LEAK OXPHOS	N NS S	Isolated mitochondria	Rat	Kidney
Chabi 2018 J Bioenerg Biomembr	2018	Chabi B, Fouret G, Lecomte J, Cortade F, Pessemesse L, Baati N, Coudray C, Lin L, Tong Q, Wrutniak-Cabello C, Casas F, Feillet-Coudray C (2018) Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition. J Bioenerg Biomembr 50:131-42.	LEAK OXPHOS	N S CIV NS	Homogenate Isolated mitochondria	Mouse	Skeletal muscle
Rodrigues 2018 Sci Rep	2018	Rodrigues APC, Camargo AF, Andjelkovic A, Jacobs HT, Oliveira MT (2018) Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase. Sci Rep 8:10882.	OXPHOS	N CIV ROX	Homogenate Oxidase;biochemical oxidation	Drosophila
Kjeld 2018 PLoS One	2018	Kjeld T, Stride N, Gudiksen A, Hansen EG, Arendrup HC, Horstmann PF, Zerahn B, Jensen LT, Nordsborg N, Bejder J, Halling JF (2018) Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers. PLoS One 13:e0201401.	OXPHOS ET LEAK	N S NS	Permeabilized tissue	Human	Skeletal muscle
Ruas 2018 Sci Rep	2018	Ruas JS, Siqueira-Santos ES, Rodrigues-Silva E, Castilho RF (2018) High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited. https://doi.org/10.1038/s41598-018-35679-8	LEAK ET ROUTINE	N	Permeabilized cells Intact cells	Human	Nervous system Other cell lines
Smenes 2018 Interact Cardiovasc Thorac Surg	2018	Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Heart
Krug 2018 Thesis	2018	Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136.	LEAK ROUTINE OXPHOS ET	N S CIV ROX	Intact cells Permeabilized cells	Rat	Other cell lines
Dejos 2018 Sci Rep	2018	Dejos C, Kuny S, Han WH, Capel H, Lemieux H, Sauvé Y (2018) Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci Rep 8:5944.	OXPHOS	N S CIV NS ROX	Homogenate	Mouse	Endothelial;epithelial;mesothelial cell
Khamoui 2018 J Dev Orig Health Dis	2018	Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Rudnicki 2018 Elife	2018	Rudnicki M, Abdifarkosh G, Nwadozi E, Ramos SV, Makki A, Sepa-Kishi DM, Ceddia RB, Perry CG, Roudier E, Haas TL (2018) Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth. Elife 7:e39780.	OXPHOS	N NS	Homogenate	Mouse	Fat
Guitart-Mampel 2018 Biochim Biophys Acta	2018	Guitart-Mampel M, Gonzalez-Tendero A, Niñerola S, Morén C, Catalán-Garcia M, González-Casacuberta I, Juárez-Flores DL, Ugarteburu O, Matalonga L, Cascajo MV, Tort F, Cortés A, Tobias E, Milisenda JC, Grau JM, Crispi F, Gratacós E, Garrabou G, Cardellach F (2018) Cardiac and placental mitochondrial characterization in a rabbit model of intrauterine growth restriction. Biochim Biophys Acta 1862:1157-67.		N ROX	Permeabilized tissue	Rabbit	Heart Genital
Ravasz 2018 Biochim Biophys Acta	2018	Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD⁺ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24.	LEAK OXPHOS	F N DQ	Isolated mitochondria	Mouse	Liver
Audia 2018 Basic Res Cardiol	2018	Audia JP, Yang XM, Crockett ES, Housley N, Haq EU, O'Donnell K, Cohen MV, Downey JM, Alvarez DF (2018) Caspase‑1 inhibition by VX‑765 administered at reperfusion in P2Y12 receptor antagonist‑treated rats provides long‑term reduction in myocardial infarct size and preservation of ventricular function. Basic Res Cardiol 113:32.	OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Fets 2018 Nat Chem Biol	2018	Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Silva Dos Santos M, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D (2018) MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG. Nat Chem Biol 14:1032-42.	OXPHOS	N	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell
Wen 2018 PLOS Pathog	2018	Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLOS Pathog 14:e1007065.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Heart Other cell lines
Carter 2018 J Appl Physiol (1985)	2018	Carter HN, Pauly M, Tryon LD, Hood DA (2018) Effect of contractile activity on PGC-1α transcription in young and aged skeletal muscle. J Appl Physiol (1985) 124:1605-15.	OXPHOS	N	Intact cells	Rat	Skeletal muscle
Fischer 2018 BMC Musculoskelet Disord	2018	Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Mikulas 2018 Dent Mater	2018	Mikulás K, Hermann P, Gera I, Komlódi T, Horváth G, Ambrus A, Tretter L (2018) Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e181.	OXPHOS ET	N S	Isolated mitochondria	Guinea pig	Nervous system
Vinel 2018 Nat Med	2018	Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradere JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C (2018) The exerkine apelin reverses age-associated sarcopenia. Nat Med 24:1360-71.	OXPHOS	N S	Permeabilized tissue	Mouse	Skeletal muscle
Kleszczynski 2018 Int J Mol Sci	2018	Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Liver
Gratl 2018 Thesis	2018	Gratl A (2018) High-resolution respirometry for measurement of mitochondrial function in PAD patients before and after revascularisation. PhD Thesis 69.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Mavroudis 2018 Eur J Cardiothorac Surg	2018	Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68.	LEAK ET OXPHOS	N S CIV NS ROX	Homogenate	Pig	Nervous system
Rodriguez-Nuevo 2018 EMBO J	2018	Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Lu 2018 Cell Rep	2018	Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Puurand 2018 Int J Mol Sci	2018	Puurand M, Tepp K, Klepinin A, Klepinina L, Shevchuk I, Kaambre T (2018) Intracellular energy-transfer networks and high-resolution respirometry: a convenient approach for studying their function. Int J Mol Sci 19:e2933.	OXPHOS	N	Permeabilized cells
Pamenter 2018 PLoS One	2018	Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Dechandt 2018 Am J Physiol Regul Integr Comp Physiol	2018	Dechandt CR, Vicentini TM, Lanfredi GP, da Silva RMP Jr, Espreafico EM, de Oliveira JAC, Faça VM, Garcia-Cairasco N, Alberici LC (2018) The highly efficient power house in the Wistar Audiogenic Rat (WAR), an epileptic rat strain. Am J Physiol Regul Integr Comp Physiol 316:R243-R254.	LEAK OXPHOS ET	N ROX	Permeabilized tissue Isolated mitochondria	Rat	Heart Skeletal muscle Liver
Chicco 2018 J Biol Chem	2018	Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71.	LEAK OXPHOS ET	F N S	Permeabilized tissue	Human	Skeletal muscle
Toledo 2018 Obesity (Silver Spring)	2018	Toledo FGS, Dubé JJ, Goodpaster BH, Stefanovic-Racic M, Coen PM, DeLany JP (2018) Mitochondrial respiration is associated with lower energy expenditure and lower aerobic capacity in African American women. Obesity (Silver Spring) 26:903-9.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Musi 2018 Aging Cell	2018	Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840.	LEAK OXPHOS ET	F N S NS	Homogenate	Mouse	Nervous system
Van Den Brink 2018 PLoS Genet	2018	Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B (2018) Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet 14:e1007627.	LEAK OXPHOS	F N S NS	Permeabilized cells	Mouse	Endothelial;epithelial;mesothelial cell
Ederer 2018 Int J Mol Sci	2018	Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M (2018) Age- and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in Drosophila melanogaster. Int J Mol Sci 19:3351.	LEAK OXPHOS	N	Isolated mitochondria	Drosophila
De Paula Martins 2018 Free Radic Biol Med	2018	de Paula Martins R, Ghisoni K, Lim CK, Aguiar AS Jr, Guillemin GJ, Latini A (2018) Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes. Free Radic Biol Med 115:371-82.	ROUTINE	N		Rat	Nervous system
Kim 2018 Free Radic Biol Med	2018	Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124:517-24.	OXPHOS	N S	Isolated mitochondria	Mouse	Nervous system
Cronin 2018 Nature	2018	Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68.	ROUTINE OXPHOS ET LEAK	N S	Permeabilized cells Intact cells	Mouse	Lymphocyte
Ignatenko 2018 Nat Commun	2018	Ignatenko O, Chilov D, Paetau I, de Miguel E, Jackson CB, Capin G, Paetau A, Terzioglu M, Euro L, Suomalainen A (2018) Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy. Nat Commun 9:70.	OXPHOS ET	N CIV NS	Homogenate	Mouse	Nervous system
Dela 2018 Acta Physiol (Oxf)	2018	Dela F, Ingersen A, Andersen NB, Nielsen MB, Petersen HHH, Hansen CN, Larsen S, Wojtaszewski J, Helge JW (2018) Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. Acta Physiol (Oxf) 226:e13245.	OXPHOS LEAK	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Van Erp 2018 Sci Rep	2018	Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405.	OXPHOS ET	F N S NS	Isolated mitochondria	Rat	Liver Kidney
Goswami 2018 Biophys J	2018	Goswami I, Perry JB, Allen ME, Brown DA, von Spakovsky MR, Verbridge SS (2018) Influence of pulsed electric fields and mitochondria-cytoskeleton interactions on cell respiration. Biophys J 114:2951-64.	OXPHOS ET	N	Intact cells	Mouse	Other cell lines
Holland 2018 Cell Death Dis	2018	Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Human	Genital
Allard 2018 J Clin Endocrinol Metab	2018	Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84.	OXPHOS	F N S Gp CIV NS	Permeabilized tissue	Human	Skeletal muscle
Manoharan 2018 Thesis	2018	Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Fishes	Heart Liver
Rajkumar 2018 Metabolism	2018	Rajkumar A, Liaghati A, Chan J, Lamothe G, Dent R, Doucet É, Rabasa-Lhoret R, Prud'homme D, Harper ME, Tesson F (2018) ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study. Metabolism 83:271-9.	OXPHOS ET	F N CIV NS	Permeabilized cells	Human Mouse	Skeletal muscle Other cell lines
Paech 2018a Toxicology	2018	Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells Isolated mitochondria	Human Mouse	Liver Other cell lines
Konopka 2018 Aging Cell	2018	Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880.	OXPHOS ET LEAK	F N NS S ROX	Permeabilized tissue	Human	Skeletal muscle
Bjoerndal 2018 Nutr Metab (Lond)	2018	Bjørndal B, Alterås EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10.	OXPHOS ET	F N ROX	Homogenate	Mouse	Liver
Tarpey 2018 Skelet Muscle	2018	Tarpey MD, Amorese AJ, Balestrieri NP, Ryan TE, Schmidt CA, McClung JM, Spangenburg EE (2018) Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function. Skelet Muscle 8:14.	OXPHOS	N S CIV NS ROX		Mouse	Skeletal muscle
Manakov 2018 J Physiol Biochem	2018	Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Rat	Heart
Dejmek 2018 Physiol Res	2018	Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643.	LEAK ROUTINE OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Intact cells	Human	Lung;gill Fibroblast
Kauppila 2018 Thesis	2018	Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart Liver
Stepanova 2018 J Neurochem	2018	Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45.	LEAK OXPHOS	N S Gp NS ROX	Isolated mitochondria	Mouse	Nervous system
Carter 2018 J Physiol	2018	Carter HN, Kim Y, Erlich AT, Zarrin-Khat D, Hood DA (2018) Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity. J Physiol 596:3567-84.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Skeletal muscle
Zhang 2018 Aging Dis	2018	Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue Homogenate	Rat	Nervous system
Groennebaek 2018 Front Physiol	2018	Groennebaek T, Jespersen NR, Jakobsgaard JE, Sieljacks P, Wang J, Rindom E, Musci RV, Bøtker HE, Hamilton KL, Miller BF, de Paoli FV, Vissing K (2018) Skeletal muscle mitochondrial protein synthesis and respiration increase with low-load blood flow restricted as well as high-load resistance training. Front Physiol 9:1796.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Du 2018 Environ Sci Technol	2018	Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11.	LEAK ET	N S NS	Isolated mitochondria	Fishes	Liver
Hsiao 2018 Anal Biochem	2018	Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20.	OXPHOS ET	F N S DQ CIV NS ROX	Intact cells	Human	Blood cells
Juarez-Flores 2018 J Transl Med	2018	Juárez-Flores DL, González-Casacuberta I, Ezquerra M, Bañó M, Carmona-Pontaque F, Catalán-García M, Guitart-Mampel M, Rivero JJ, Tobias E, Milisenda JC, Tolosa E, Marti MJ, Fernández-Santiago R, Cardellach F, Morén C, Garrabou G (2018) Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2^G2019S -Parkinson's disease. J Transl Med 16:160.		N	Permeabilized cells	Human	Fibroblast
Lai 2018 Acta Physiol (Oxf)	2018	Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopulations from skeletal muscle: optimizing recovery and preserving integrity. Acta Physiol (Oxf) e13182. doi: 10.1111/apha.13182.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Skeletal muscle
Larsen 2018 Physiol Rep	2018	Larsen S, Lundby AM, Dandanell S, Oberholzer L, Keiser S, Andersen AB, Haider T, Lundby C (2018) Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. Physiol Rep 6:e13793.	OXPHOS ET LEAK	F N NS	Permeabilized tissue	Human	Skeletal muscle
Ryan 2018 JCI Insight	2018	Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235.	OXPHOS LEAK	N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Sirsat 2018 Comp Biochem Physiol A Mol Integr Physiol	2018	Sirsat SKG, Dzialowski EM (2018) Ontogeny of skeletal and cardiac muscle mitochondria oxygen fluxes in two breeds of chicken. Comp Biochem Physiol A Mol Integr Physiol 215:20-7.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Birds	Heart Skeletal muscle
Becker 2018 EMBO Rep	2018	Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Liver Fat
Barca 2018 Hum Mol Genet	2018	Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12.	LEAK ROUTINE OXPHOS ET	F N S DQ NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Harmuth 2018 Front Mol Neurosci	2018	Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368.	LEAK ET ROUTINE OXPHOS	N S	Homogenate Intact cells	Mouse	Fibroblast
Hayward 2018 Thesis	2018	Hayward L (2018) The effect of anoxia on mitochondrial function in a hibernator (Ictidomys tridecemlineatus). Master's Thesis 57.	OXPHOS LEAK	N NS	Isolated mitochondria	Other mammals	Liver
Boutoual 2018 Sci Rep	2018	Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Razak 2018 RUMeS	2018	Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Rodrigues 2018 Free Radic Biol Med	2018	Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Drosophila
Nacarelli 2018 Geroscience	2018	Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C (2018) Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. Geroscience 40:243-56.	OXPHOS	F N S NS	Isolated mitochondria	Human	Heart Fibroblast
Walczak 2018 FASEB J	2018	Walczak J, Dębska-Vielhaber G, Vielhaber S, Szymański J, Charzyńska A, Duszyński J, Szczepanowska J (2018) Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics. FASEB J 33:4388-403.	OXPHOS LEAK ROUTINE	N S	Permeabilized cells	Human	Fibroblast
Cejvanovic 2018 Free Radic Biol Med	2018	Cejvanovic V, Kjær LK, Bergholdt HKM, Torp-Pedersen A, Henriksen T, Weimann A, Ellervik C, Poulsen HE (2018) Iron induced RNA-oxidation in the general population and in mouse tissue. Free Radic Biol Med 115:127-35.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Siira 2018 EMBO Rep	2018	Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart
Lica 2018 Stem Cells Dev	2018	Lica JJ, Grabe GJ, Heldt M, Misiak M, Bloch P, Serocki M, Switalska M, Wietrzyk J, Baginski M, Hellmann A, Borowski E, Skladanowski A (2018) Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells. Stem Cells Dev 27:488-513.	LEAK ROUTINE ET	N		Human Mouse	Heart Blood cells Other cell lines
Yang 2018 Cell Death Dis	2018	Yang F, Wu R, Jiang Z, Chen J, Nan J, Su S, Zhang N, Wang C, Zhao J, Ni C, Wang Y, Hu W, Zeng Z, Zhu K, Liu X, Hu X, Zhu W, Yu H, Huang J, Wang J (2018) Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation. Cell Death Dis 9:556.		N S CIV NS ROX	Intact cells	Mouse
Kovalcikova 2018 Thesis	2018	Kovalčíková J (2018) Functional characterisation of new components of mitochondrial proteome. PhD Thesis p104.	LEAK OXPHOS ET	N NS	Homogenate	Mouse Rat	Heart Liver
Marie 2018 Cell Death Dis	2018	Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis 9:287.	LEAK OXPHOS ET	N S NS	Permeabilized cells		Endothelial;epithelial;mesothelial cell
Ferri 2018 Eur J Appl Physiol	2018	Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ (2018) Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia. Eur J Appl Physiol 118:1641-52.	LEAK OXPHOS	N	Permeabilized tissue	Rat	Heart Skeletal muscle
Schiffer 2018 Am J Physiol Renal Physiol	2018	Schiffer TA, Gustafsson H, Palm F (2018) Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment. Am J Physiol Renal Physiol 315:F677-F681.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Kidney
Tosi 2018 J Bioenerg Biomembr	2018	Tosi I, Art T, Cassart D, Farnir F, Ceusters J, Serteyn D, Lemieux H, Votion DM (2018) Altered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy. J Bioenerg Biomembr 50:379-90.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Garcia-Roche 2018 Redox Biol	2018	García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12.	LEAK OXPHOS ET	N NS ROX S	Permeabilized tissue	Rat Bovines	Liver
Cecatto 2018 J Cell Biochem	2018	Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86.	LEAK OXPHOS ET	N	Permeabilized cells Permeabilized tissue	Rat	Heart Nervous system Liver
Maurya 2018 Cell Rep	2018	Maurya SK, Herrera JL, Sahoo SK, Reis FCG, Vega RB, Kelly DP, Periasamy M (2018) Sarcolipin signaling promotes mitochondrial biogenesis and oxidative metabolism in skeletal muscle. Cell Rep 24:2919-31.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Schiffer 2018 PLoS One	2018	Schiffer TA, Christensen M, Gustafsson H, Palm F (2018) The effect of inactin on kidney mitochondrial function and production of reactive oxygen species. PLoS One 13:e0207728.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Kidney
Efimova 2018 Thesis	2018	Efimova I (2018) Structural composition and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	HEK
Silva 2018 Nat Cell Biol	2018	Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH (2018) EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Nat Cell Biol 20:162-74.	OXPHOS ET	N S NS ROX	Permeabilized tissue		Islet cell;pancreas;thymus
Ounpuu 2018 Biochem Cell Biol	2018	Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print].	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Jelenik 2018 Diabetes	2018	Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702.	LEAK OXPHOS	F N NS ROX	Permeabilized tissue Isolated mitochondria	Human Mouse	Heart
Menezes-Filho 2018 Biochim Biophys Acta Bioenerg	2018	Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35.	OXPHOS ET	N S	Isolated mitochondria	Mouse	Liver
Coleman 2018 Sci Rep	2018	Coleman V, Sa-Nguanmoo P, Koenig J, Schulz TJ, Grune T, Klaus S, Kipp AP, Ost M (2018) Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep 8:2446.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Kolb 2018 J Am Soc Nephrol	2018	Kolb AL, Corridon PR, Zhang S, Xu W, Witzmann FA, Collett JA, Rhodes GJ, Winfree S, Bready D, Pfeffenberger ZJ, Pomerantz JM, Hato T, Nagami GT, Molitoris BA, Basile DP, Atkinson SJ, Bacallao RL (2018) Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection. J Am Soc Nephrol 29:1154-64.	OXPHOS	N NS	Isolated mitochondria		Kidney
Furlanetto 2018 Physiol Plant	2018	Furlanetto ALDM, Cadena SMSC, Martinez GR, Ferrando B, Stevnsner T, Møller IM (2018) Short-term high temperature treatment reduces viability and inhibits respiration and DNA repair enzymes in Araucaria angustifolia cells. Physiol Plant 166:513-24.	ET ROUTINE	N CIV ROX	Intact cells	Plants
Christensen 2018 Diabetes Metab Res Rev	2018	Christensen M, Schiffer TA, Gustafsson H, Krag SP, Nørregaard R, Palm F (2018) Metformin attenuates renal medullary hypoxia in diabetic nephropathy through uncoupling protein-2 inhibition. Diabetes Metab Res Rev 21:e3091.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Kidney
Singh 2018 Arch Toxicol	2018	Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504.	OXPHOS LEAK	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Kamunde 2018 Free Radic Biol Med	2018	Kamunde C, Sharaf M, MacDonald N (2018) H₂O₂ metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.	LEAK	N ROX	Isolated mitochondria	Fishes	Heart Liver
Kang 2018 Exp Mol Med	2018	Kang YC, Son M, Kang S, Im S, Piao Y, Lim KS, Song MY, Park KS, Kim YH, Pak YK (2018) Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson's disease models. Exp Mol Med 50:105.	OXPHOS	N	Isolated mitochondria	Human	Nervous system
Zimin 2018 Br J Anaesth	2018	Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32.	OXPHOS LEAK	N S ROX	Isolated mitochondria	Mouse	Nervous system
Stein 2018 Cell Rep	2018	Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Heart Skeletal muscle
Fink 2018 J Biol Chem	2018	Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41. https://doi.org/10.1074/jbc.RA118.005144	OXPHOS	N S NS	Isolated mitochondria	Mouse	Skeletal muscle
Oemer 2018 Proc Nat Acad Sci U S A	2018	Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Intact cells Permeabilized cells	Human	HeLa
Perks 2018 Cell Rep	2018	Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42.	LEAK OXPHOS ET	N Gp S	Isolated mitochondria	Mouse	Heart
Paech 2018b Toxicology	2018	Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.	LEAK OXPHOS ET	N S DQ CIV ROX NS	Isolated mitochondria	Mouse	Liver
Wang 2018 J Nutr Biochem	2018	Wang Y, Fouret G, Bonafos B, Blachnio-Zabielska A, Leroy T, Crouzier D, Barea B, Gaillet S, Moro C, Lecomte J, Coudray C, Feillet-Coudray C (2018) Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats. J Nutr Biochem 64:182-97.	OXPHOS LEAK	N NS	Isolated mitochondria	Rat	Skeletal muscle
Petiz 2018 Chem Biol Interact	2018	Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Liver
Rampello 2018 Microb Cell	2018	Rampello NG, Stenger M, Westermann B, Osiewacz HD (2018) Impact of F₁F_o-ATP-synthase dimer assembly factors on mitochondrial function and organismic aging. Microb Cell 5:198–207.	OXPHOS	N CIV	Isolated mitochondria	Fungi
Ost 2018 Curr Opin Clin Nutr Metab Care	2018	Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells		Blood cells Platelet Skeletal muscle Liver Fat
Ale-Agha 2018 PLOS Biol	2018	Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J (2018) CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. PLOS Biol 6:e2004408.	OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart
Mahapatra 2018 Clin Sci (Lond)	2018	Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690	LEAK OXPHOS ET	F N S Gp NS Other combinations ROX	Permeabilized cells	Human	Nervous system Blood cells
Martins 2018 Oxid Med Cell Longev	2018	Martins IK, de Carvalho NR, Macedo GE, Rodrigues NR, Ziech CC, Vinadé L, Filho VMB, Menezes IA, Franco J, Posser T (2018) Anacardium microcarpum promotes neuroprotection dependently of AKT and ERK phosphorylation but does not prevent mitochondrial damage by 6-OHDA. Oxid Med Cell Longev 2018:2131895.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Chicken	Nervous system
Sokolov 2018 Mitochondrion	2018	Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Molluscs	Lung;gill
Ko 2018 Pflugers Arch	2018	Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75.	LEAK OXPHOS	N ROX	Isolated mitochondria	Rat	Heart
McLaughlin 2018 Biochem Biophys Res Commun	2018	McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48.		N S F	Isolated mitochondria	Mouse	Heart
Fouret 2018 Br J Nutr	2018	Fouret G, Gaillet S, Lecomte J, Bonafos B, Djohan F, Barea B, Badia E, Coudray C, Feillet-Coudray C (2018) 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. Br J Nutr 119:368-80.	OXPHOS	N NS		Rat	Liver
Logan 2018 Thesis	2018	Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Zebrafish	Skeletal muscle
Dohlmann 2018 Physiol Rep	2018	Dohlmann TL, Hindsø M, Dela F, Helge JW, Larsen S (2018) High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle. Physiol Rep 6:e13857.	OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle Fat
McWilliams 2018 Open Biol	2018	McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK (2018) Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol 8:180108.	LEAK OXPHOS ET	N	Homogenate	Mouse	Nervous system
Dawson 2018 Acta Physiol (Oxf)	2018	Dawson NJ, Lyons SA, Henry DA, Scott GR (2018) Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol (Oxf) 223:e13030.	LEAK OXPHOS	N CIV NS	Permeabilized tissue	Other mammals	Skeletal muscle
Cardinale 2018 Physiol Rep	2018	Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Skeletal muscle
Wuest 2018 Cell Metab	2018	Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T (2018) Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster. Cell Metab 27:1026-39.	OXPHOS	N S CIV	Intact cells	Mouse	Skeletal muscle
Gam 2018 Acta Diabetol	2018	Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010.	LEAK OXPHOS	F N S NS	Isolated mitochondria	Human	Genital
Real-Hohn 2018 bioRxiv	2018	Real-Hohn A, Navegantes C, Ramos K, Ramos-Filho D, Cahuê F, Galina A, Salerno V (2018) Hexokinase: a central player in the synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations. bioRxiv doi: https://doi.org/10.1101/389668.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Rat	Skeletal muscle
Fox 2018 Thesis	2018	Fox JC (2018) FROST450, a novel microtubule targeting agent: resistance and cross-resistance in an ovarian cancer cell line. Bachelor's Thesis 27.	LEAK OXPHOS ET	N NS ROX	Intact cells	Human	Genital
Leckey 2018 FASEB J	2018	Leckey JJ, Hoffman NJ, Parr EB, Devlin BL, Trewin AJ, Stepto NK, Morton JP, Burke LM, Hawley JA (2018) High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. FASEB J 32:2979-91.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Chung 2018 J Exp Biol	2018	Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458.	LEAK OXPHOS ET	F N S CIV NS ROX	Isolated mitochondria	Fishes	Liver
Britto 2018 BMC Biol	2018	Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65. https://doi.org/10.1186/s12915-018-0525-4	LEAK OXPHOS	F N NS Other combinations	Permeabilized cells Isolated mitochondria	Mouse	Skeletal muscle
Francisco 2018 J Neurochem	2018	Francisco A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. J Neurochem 147:663-77.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Nervous system
Thrush 2018 Int J Obes (Lond)	2018	Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62.	LEAK OXPHOS ET	F N CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Scaini 2018 Eur Neuropsychopharmacol	2018	Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Other cell lines Lymphocyte
Robb 2018 J Biol Chem	2018	Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293:9869-79. https://doi.org/10.1074/jbc.RA118.003647	ET	N S ROX	Isolated mitochondria	Rat	Heart
Von Schulze 2018 J Physiol	2018	Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α, and BNIP3 mediated mitophagy. J Physiol 596:6157-71.	OXPHOS ET	F N NS	Isolated mitochondria	Mouse	Liver
Comelli 2017 J Bioenerg Biomembr	2017	Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52.	LEAK ROUTINE OXPHOS ET	N Gp CIV NS ROX	Intact cells Permeabilized cells	Human	Nervous system
Martins 2017 Thesis	2017	Martins WC (2017) Estudo do efeito protetor da atorvastatina e dos eventos iniciais da neurotoxicidade induzida pelo peptídeo β-amilóide (Aβ1-40) em camundongos. Doctoral Thesis p85.	LEAK OXPHOS ET	N NS ROX	Homogenate	Mouse	Nervous system
Wolff 2017 Thesis	2017	Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Horse Human	Skeletal muscle
Broatch 2017 Am J Physiol Regul Integr Comp Physiol	2017	Broatch JR, Petersen A, Bishop DJ (2017) Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 313:R372-84.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Koit 2017 Oxid Med Cell Longev	2017	Koit A, Shevchuk I, Ounpuu L, Klepinin A, Chekulayev V, Timohhina N, Tepp K, Puurand M,Truu L, Heck K, Valvere V, Guzun R, Kaambre T (2017) Mitochondrial respiration in human colorectal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640.	OXPHOS LEAK	N S CIV ROX NS	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Han 2017 Invest Ophthalmol Vis Sci	2017	Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest Ophthalmol Vis Sci 58:3826-39.	LEAK OXPHOS	N S CIV NS ROX	Homogenate	Rat	Nervous system
Lores-Arnaiz 2017 J Neurochem	2017	Lores-Arnaiz S, Karadayian AG, Gutnisky A, Rodríguez de Lores Arnaiz G (2017) The low affinity neurotensin receptor antagonist levocabastine impairs brain nitric oxide synthesis and mitochondrial function by independent mechanisms. J Neurochem 143:684-96.	LEAK OXPHOS ET	N NS		Rat	Nervous system
Gifford 2017 J Appl Physiol (1985)	2017	Gifford JR, Trinity JD, Kwon OS, Layec G, Garten RS, Park SY, Nelson AD, Richardson RS (2017) Altered skeletal muscle mitochondrial phenotype in COPD: disease versus disuse. J Appl Physiol (1985) 124:1045-53.	OXPHOS	N S NS	Permeabilized tissue	Human	Skeletal muscle
Sidlauskas 2017 Neurosci Lett	2017	Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14.	OXPHOS LEAK ROUTINE ET	N S	Intact cells Permeabilized cells	Rat	Nervous system Other cell lines
Teplova 2017 Toxicol Lett	2017	Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17.	OXPHOS LEAK	N S CIV	Isolated mitochondria	Rat	Liver
Paech 2017 Arch Toxicol	2017	Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells	Human	Liver Other cell lines
Yu 2017 Free Radic Biol Med	2017	Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410.	LEAK OXPHOS	F N CIV ROX	Permeabilized tissue	Mouse	Heart
Robinson 2017 Cell Metabol	2017	Robinson MM, Dasari S, Konopka AR, Johnson ML, Manjunatha S, Esponda RR, Carter RE, Lanza IR, Nair KS (2017) Enhanced protein translation underlies improved metabolic and physical adaptations to different exercise training modes in young and old humans. Cell Metab 25:581-92.	OXPHOS	N NS	Isolated mitochondria	Human	Skeletal muscle
Irgebay 2017 Breast	2017	Irgebay Z, Yeszhan B, Sen B, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2017) Danazol alters mitochondria metabolism of fibrocystic breast Mcf10A cells. Breast 35:55-62.	ET	N S CIV NS ROX	Permeabilized cells	Human	Genital
Hu 2017 Proc Natl Acad Sci U S A	2017	Hu H, Nan J, Sun Y, Zhu D, Xiao C, Wang Y, Zhu L, Wu Y, Zhao J, Wu R, Chen J, Yu H, Hu X, Zhu W, Wang J (2017) Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A 114:11908-13.	OXPHOS	N S CIV NS ROX	Isolated mitochondria	Mouse
Horscroft 2017 Proc Natl Acad Sci U S A	2017	Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ (2017) Metabolic basis to Sherpa altitude adaptation. Proc Natl Acad Sci U S A 114:6382–7. https://doi.org/10.1073/pnas.1700527114	LEAK OXPHOS ET	F N S NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Jang 2017 Biol Open	2017	Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9.	LEAK ROUTINE ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Rontoyanni 2017 Shock	2017	Rontoyanni VG, Malagaris I, Herndon DN, Rivas E, Capek KD, Delgadillo AD, Bhattarai N, Elizondo A, Voigt CD, Finnerty CC, Suman OE, Porter C (2017) Skeletal muscle mitochondrial function is determined by burn severity, sex and sepsis, and is associated with glucose metabolism and functional capacity in burned children. Shock 50:141-48.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Mitroshina 2017 Mod Technol Med	2017	Mitroshina ЕV, Abogessimengane BZ, Urazov МD, Hamraoui I, Mishchenko ТА, Astrakhanova ТА, Shchelchkova NА, Lapshin RD, Shishkina ТV, Belousova II, Mukhina IV, Vedunova МV (2017) Adaptive role of glial cell line-derived neurotrophic factor in cerebral ischemia. Mod Technol Med 9:68-76.	OXPHOS LEAK	N S	Isolated mitochondria	Mouse	Nervous system
Schmidt 2017 J Vasc Surg	2017	Schmidt CA, Ryan TE, Lin CT, Inigo MM, Green TD, Brault JJ, Spangenburg EE, McClung JM (2017) Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia. J Vasc Surg 65:1504-1514.	OXPHOS ET LEAK	N S CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Ho 2017 Thesis	2017	Ho DH (2017) The role of MLQ protein in structure and function of mammalian ATP synthase. Master's Thesis p84.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells	Human	Kidney
Masson 2017 Sci Rep	2017	Masson SWC, Hedges CP, Devaux JBL, James CS, Hickey AJR (2017) Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis. Sci Rep 7:13107.	OXPHOS ET	N Gp NS	Permeabilized tissue	Hexapods	Skeletal muscle
Yeh 2017 Thesis	2017	Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells Permeabilized tissue	Human Fishes	Liver
Morrow 2017 Proc Natl Acad Sci U S A	2017	Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10.	ROUTINE OXPHOS LEAK	N NS ROX Other combinations	Permeabilized tissue		Skeletal muscle
Kenny 2017 Diabetologia	2017	Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ (2017) Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance. Diabetologia 60:1491-501.	LEAK OXPHOS ET	N S CIV NS F	Permeabilized tissue	Human	Skeletal muscle
Yeh 2017 Aquat Toxicol	2017	Yeh A, Marcinek DJ, Meador JP, Gallagher EP (2017) Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon. Aquat Toxicol 190:21-31.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Liver
Sivitz 2017 Neuromethods	2017	Sivitz WI (2017) Techniques to investigate bioenergetics of mitochondria. In: Strack S, Usachev Y (eds) Techniques to investigate mitochondrial function in neurons. Neuromethods 123:67-94. Humana Press, New York. https://doi.org/10.1007/978-1-4939-6890-9_4	LEAK OXPHOS ET	F N S	Isolated mitochondria Intact cells
Briston 2017 Sci Rep	2017	Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492.	OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Liver
Lopez 2017 PLOS ONE	2017	López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.	LEAK ROUTINE OXPHOS	N S NS	Isolated mitochondria	Mouse
Wang 2017 Mol Cell	2017	Wang X, Auwerx J (2017) Systems phytohormone responses to mitochondrial proteotoxic stress. Mol Cell 68:540-51.	OXPHOS	N NS	Isolated mitochondria	Plants
Knuppertz 2017 Aging Cell	2017	Knuppertz L, Osiewacz HD (2017) Autophagy compensates impaired energy metabolism in CLPXP-deficient Podospora anserina strains and extends healthspan. Aging Cell 16:704-15.	OXPHOS	N S CIV NS	Isolated mitochondria	Fungi
Kiprowska 2017 Biochim Biophys Acta	2017	Kiprowska MJ, Stepanova A, Todaro DR, Galkin A, Haas A, Wilson SM, Figueiredo-Pereira ME (2017) Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta 1863:1157-70.	OXPHOS	N NS	Isolated mitochondria	Rat	Nervous system
Abdurrachim 2017 Cardiovasc Res	2017	Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schäfers M, Nicolay K, Faber C, Hermann S, Prompers JJ (2017) Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 113:1148-60.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart
Krylova 2017 Biomed Khim	2017	Krylova TD, Tsygankova PG, Itkis YS, Sheremet NL, Nevinitsyna TA, Mikhaylova SV, Zakharova EY (2017) High resolution respirometry in diagnostic of mitochondrial disorders caused by mitochondrial complex I deficiency. Biomed Khim 63:327-33.	ET	N S NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Harisseh 2017 Basic Res Cardiol	2017	Harisseh R, Pillot B, Gharib A, Augeul L, Gallo-Bona N, Ferrera R, Loufouat J, Delale T, Allas S, Abribat T, Crola Da Silva C, Ovize M (2017) Unacylated ghrelin analog prevents myocardial reperfusion injury independently of permeability transition pore. Basic Res Cardiol 112:4.	OXPHOS ET	N S CIV ROX	Permeabilized cells	Mouse	Heart
Pfeiffer 2017 Free Radic Biol Med	2017	Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9.	LEAK ROUTINE OXPHOS ET	N NS ROX	Permeabilized cells	Mouse	Fibroblast
Sivertsson 2017 Am J Physiol Renal Physiol	2017	Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Kidney
Zhang 2017 J Am Heart Assoc	2017	Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945.	LEAK OXPHOS	N	Isolated mitochondria	Rabbit	Heart
Pecinova 2017 Oxid Med Cell Longev	2017	Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603.	LEAK OXPHOS ET	N S Gp NS	Isolated mitochondria	Rat	Fat
Scheede-Bergdahl 2017 Can J Physiol Pharmacol	2017	Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9.	LEAK OXPHOS	F N CIV NS ROX	Permeabilized tissue	Mouse	Endothelial;epithelial;mesothelial cell
Chung 2017 Sci Rep	2017	Chung DJ, Morrison PR, Bryant HJ, Jung E, Brauner CJ, Schulte PM (2017) Intraspecific variation and plasticity in mitochondrial oxygen binding affinity as a response to environmental temperature. Sci Rep 7:16238.	OXPHOS	F N NS	Isolated mitochondria	Fishes	Liver
Van Schaardenburgh 2017 J Vasc Surg	2017	Van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson E (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. J Vasc Surg 65:1473-82.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Van den Berg 2017 Am J Respir Crit Care Med	2017	van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC (2017) Diaphragm atrophy and weakness in the absence of mitochondrial dysfunction in the critically ill. Am J Respir Crit Care Med 196:1544-58.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Uppala 2017 Biochem Biophys Res Commun	2017	Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51.	OXPHOS LEAK ET	N NS	Permeabilized cells	Human Mouse	HEK Fibroblast
Napa 2017 Int J Dent	2017	Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT (2017) LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Ortega-Dominguez 2017 Food Chem Toxicol	2017	Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85.	LEAK ROUTINE OXPHOS	N NS	Isolated mitochondria
Bowen 2017 J Am Heart Assoc	2017	Bowen TS, Brauer D, Rolim NPL, Bækkerud FH, Kricke A, Ormbostad Berre AM, Fischer T, Linke A, da Silva GJ, Wisloff U, Adams V (2017) Exercise training reveals inflexibility of the diaphragm in an animal model of patients with obesity-driven heart failure with a preserved ejection fraction. J Am Heart Assoc 6. pii: e006416.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Skeletal muscle
Nelskylae 2017 Resuscitation	2017	Nelskylä A, Nurmi J, Jousi M, Schramko A, Mervaala E, Ristagno G, Skrifvars MB (2017) The effect of 50% compared to 100% inspired oxygen fraction on brain oxygenation and post cardiac arrest mitochondrial function in experimental cardiac arrest. Resuscitation 116:1-7.	OXPHOS ET	F N S NS	Homogenate	Pig	Heart
Tegelberg 2017 Orphanet J Rare Dis	2017	Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73.	LEAK ROUTINE OXPHOS ET	N NS ROX S	Permeabilized cells	Human Mouse	Blood cells Platelet
Zhou 2017 Biochim Biophys Acta	2017	Zhou L, Wang W, Hoppel C, Liu J, Zhu X (2017) Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits. Biochim Biophys Acta 1863:2791-5.	OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Fibroblast
Goedecke 2017 JMIR Res Protoc	2017	Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T (2017) An exercise intervention to unravel the mechanisms underlying insulin resistance in a cohort of black South African women: Protocol for a randomized controlled trial. JMIR Res Protoc 03/10/2017:9098.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle Fat
McFarlane 2017 Am J Physiol Regul Integr Comp Physiol	2017	McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42.	LEAK ROUTINE OXPHOS	F N	Isolated mitochondria Intact cells	Other mammals	Fat
Svensson 2017 Acta Physiol (Oxf)	2017	Svensson K, LaBarge SA, Martins VF, Schenk S (2017) Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis. Acta Physiol (Oxf) 221:193-203.	OXPHOS ET LEAK	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Park 2017 Metab Brain Dis	2017	Park HS, Cho HS, Kim TW (2017) Physical exercise promotes memory capability by enhancing hippocampal mitochondrial functions and inhibiting apoptosis in obesity-induced insulin resistance by high fat diet. Metab Brain Dis 33:283-92.	OXPHOS LEAK	N NS	Permeabilized tissue	Mouse	Nervous system
Galambo 2017 Thesis	2017	Galambo D (2017) The effect of cardiolipin on vascular smooth muscle cell dedifferentiation, function, and mitochondrial respiration. Master's Thesis p.90.	LEAK OXPHOS	F N CIV NS ROX	Permeabilized tissue	Mouse	Endothelial;epithelial;mesothelial cell
Miller 2017 PLOS ONE	2017	Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874.	OXPHOS ET LEAK	F N S NS ROX	Permeabilized tissue	Dog	Skeletal muscle
Braz-Mota 2017 Thesis	2017	Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78.	LEAK OXPHOS ET	N NS ROX	Homogenate	Fishes	Lung;gill
Dixit 2017 Free Radic Biol Med	2017	Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Heart
Ramirez 2017 Cell Metab	2017	Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M (2017) Mitochondrial dynamics mediated by mitofusin 1 is required for POMC neuron glucose-sensing and insulin release control. Cell Metab 25:1390-9.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Nervous system
Cervoni 2017 J Exp Biol	2017	Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46.	LEAK ROUTINE OXPHOS ET	N ROX	Intact cells
De Velasco 2017 Br J Nutr	2017	de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Mouse	Liver
Krishnathas 2017 Med Chem Comm	2017	Krishnathas R, Bonke E, Dröse S, Zickermann V, Nasiri HR (2017) Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I. Med Chem Comm 8:657-61.	OXPHOS	N S	Isolated mitochondria	Rat	Heart
Jackson 2017 Cancer Res	2017	Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV (2017) Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation. Cancer Res 77:5795-807.	LEAK OXPHOS	N S NS	Intact cells	Mouse	Liver
Grassi 2017 J Appl Physiol (1985)	2017	Grassi B, Majerczak J, Bardi E, Buso A, Comelli M, Chlopicki S, Guzik M, Mavelli I, Nieckarz Z, Salvadego D, Tyrankiewicz U, Skórka T, Bottinelli R, Zoladz JA, Pellegrino MA (2017) Exercise training in Tgα_q*44 mice during the progression of chronic heart failure: cardiac vs. peripheral (soleus muscle) impairments to oxidative metabolism. J Appl Physiol (1985) 123:326-36.	LEAK OXPHOS ET	N NS S	Permeabilized tissue	Mouse	Skeletal muscle
Emmett 2017 Nature	2017	Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-8.	LEAK OXPHOS	F N S CIV ROX	Homogenate	Mouse	Fat
Xu 2017 Free Radic Biol Med	2017	Xu J, Bian X, Liu Y, Hong L, Teng T, Sun Y, Xu Z (2017) Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart. Free Radic Biol Med 106:208-18.	OXPHOS	N	Isolated mitochondria	Rat	Heart
Kudin 2017 Int J Mol Sci	2017	Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS (2017) Mitochondrial liver toxicity of valproic acid and its acid derivatives is related to inhibition of α-lipoamide dehydrogenase. Int J Mol Sci 18. pii: E1912.	OXPHOS	F N	Isolated mitochondria	Rat	Nervous system Liver
Darrell 2017 US Patent	2017	Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1.	LEAK OXPHOS	F N S ROX	Permeabilized tissue	Human Rat	Skeletal muscle
De Lourdes Jorge 2017 Transplant Proc	2017	de Lourdes Jorge G, Dos Reis Tártaro R, Fazzio Escanhoela CA, Boin IFSF (2017) Later evaluation of ischemia and reperfusion by the Pringle maneuver in Wistar rats, demonstrating that hepatic lesions can be reversible. Transplant Proc 49:898-901.	LEAK OXPHOS ET	N	Intact cells	Rat	Liver
Eckert 2017 Aging Dis	2017	Eckert SH, Gaca J, Kolesova N, Friedland K, Eckert GP, Muller WE (2017) Mitochondrial pharmacology of Dimebon (Latrepirdine) calls for a new look at its possible therapeutic potential in Alzheimer’s Disease. Aging Dis 10.14336/AD.2017.1014.	OXPHOS ET	N CIV NS		Human	Kidney HEK
Selwood 2017 US Patent	2017	Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Schoenfeld 2017 Neurochem Int	2017	Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77.	OXPHOS LEAK	F N	Isolated mitochondria	Rat	Nervous system Liver
Mahalingam 2017 J Physiol	2017	Mahalingam S, McClelland GB, Scott GR (2017) Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol 595:4785-801.	LEAK OXPHOS	N CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Hals 2017 Physiol Rep	2017	Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V (2017) Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiol Rep 5. pii: e13447.	LEAK OXPHOS ET	N	Permeabilized cells	Human Mouse	Islet cell;pancreas;thymus
Du 2017 Evolution	2017	Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52.	LEAK OXPHOS ET	N NS ROX S	Isolated mitochondria	Fishes	Liver
Djordjevic 2017 Neuroscience	2017	Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92.	ROUTINE OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Nervous system
Radenkovic 2017 Biochem Pharmacol	2017	Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Other cell lines
Victor 2017 Thesis	2017	Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells	Rat	Fibroblast
Mottahedin 2017 J Cereb Blood Flow Metab	2017	Mottahedin A, Svedin P, Nair S, Mohn CJ, Wang X, Hagberg H, Ek J, Mallard C (2017) Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain. J Cereb Blood Flow Metab 37:1192-8.	LEAK OXPHOS ET	N	Isolated mitochondria	Mouse	Nervous system
Herledan 2017 Thesis	2017	Herledan G (2017) Le role de SRF au cours de l'atrophie du muscle squelettique adulte & dans les cellules satellites. Diploma Thesis p166.	LEAK OXPHOS ET	N CIV NS		Mouse	Skeletal muscle
Pereira 2017 EMBO J	2017	Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED (2017) OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J 36:2126-45.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Westerlund 2017 Pediatr Res	2017	Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Platelet Blood cells
Dallon 2017 Biochem J	2017	Dallon BW, Parker BA, Hodson AE, Tippetts TS, Harrison ME, Appiah MMA, Witt JE, Gibbs JL, Gray HM, Sant TM, Bikman BT (2017) Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice. Biochem J 475:561-9.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle Fat
Ravasz 2017 Neurochem Int	2017	Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2017) Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int 109:41-53.	OXPHOS	N S NS	Isolated mitochondria	Mouse	Nervous system Liver
Mueller 2017 Orphanet J Rare Dis	2017	Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Herbst 2017 Appl Physiol Nutr Metab	2017	Herbst EAF, George MAJ, Brebner K, Holloway GP, Kane DA (2017) Lactate is oxidized outside of the mitochondrial matrix in rodent brain. Appl Physiol Nutr Metab 43:467-74.	OXPHOS	N	Permeabilized tissue	Mouse Rat	Nervous system
Joergensen 2017 Physiol Rep	2017	Jørgensen W, Rud KA, Mortensen OH, Frandsen L, Grunnet N, Quistorff B (2017) Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle. Physiol Rep 5. pii: e13207.	LEAK OXPHOS	F N NS	Isolated mitochondria	Rat	Skeletal muscle
Crouch 2017 PLOS ONE	2017	Crouch ML, Knowels G, Stuppard R, Ericson NG, Bielas JH, Marcinek DJ, Syrjala KL (2017) Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects. PLOS ONE 12:e0181086.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Min 2017 Skelet Muscle	2017	Min K, Lawan A, Bennett AM (2017) Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis. Skelet Muscle 7:21.	LEAK OXPHOS	N	Permeabilized tissue	Mouse	Skeletal muscle
Mathers 2017 J Comp Physiol B	2017	Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34.	LEAK OXPHOS	N S CIV ROX DQ	Intact cells Isolated mitochondria	Other mammals	Liver
Xiong 2017 J Am Heart Assoc	2017	Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell
Friederich 2017 Hum Mol Genet	2017	Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16.	ROUTINE OXPHOS ET LEAK	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Khalifa 2017 Physiol Rep	2017	Khalifa AR, Abdel-Rahman EA, Mahmoud AM, Ali MH, Noureldin M, Saber SH, Mohsen M, Ali SS (2017) Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep 5. pii: e13125.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Heart Nervous system
Fisar 2017 Indian J Biochem Biophys	2017	Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Pig	Nervous system
Ladd 2017 Brain Res	2017	Ladd AC, Brohawn DG, Thomas RR, Keeney PM, Berr SS, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Bennett JP (2017) RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency. Brain Res 1667:74-83.	LEAK OXPHOS	N CIV S	Homogenate	Rat	Nervous system
Rodrigues-Silva 2017 J Neurooncol	2017	Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Isolated mitochondria Intact cells	Rat	Nervous system
Lou 2017 Physiol Rep	2017	Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M (2017) Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol Rep 5 pii: e13388.	LEAK OXPHOS	F N CIV NS		Rat	Heart
Valis 2017 Oncotarget	2017	Vališ K, Grobárová V, Hernychová L, Bugáňová M4, Kavan D, Kalous M, Černý J, Stodůlková E, Kuzma M, Flieger M, Černý J, Novák P (2017) Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. Oncotarget 8:103137-53.	OXPHOS	N CIV NS	Isolated mitochondria	Rat	Liver
Greggio 2017 Cell Metab	2017	Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, Cantó C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Neckar 2017 Clin Sci (Lond)	2017	Neckar J, Svatonova A, Weissova R, Drahota Z, Zajickova P, Brabcova I, Kolar D, Alanova P, Vasinova J, Silhavy J, Hlavackova M, Tauchmannova K, Milerova M, Ostadal B, Cervenka L, Zurmanova J, Kalous M, Novakova O, Novotny J, Pravenec M, Kolar F (2017) Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats. Clin Sci (Lond) 131:865-81.	LEAK OXPHOS	N CIV NS	Homogenate Isolated mitochondria	Rat	Heart
Xhani 2017 Thesis	2017	Xhani M (2017) Cellular redox homeostasis and environmental toxicity. Dissertation p110.	OXPHOS	N S CIV ROX	Permeabilized cells	Human	Liver Other cell lines
Derungs 2017 Mol Psychiatry	2017	Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66^Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14.	LEAK OXPHOS ET	N	Isolated mitochondria	Mouse	Nervous system
Krycer 2017 Biochem Biophys Res Commun	2017	Krycer JR, Fisher-Wellman KH, Fazakerley DJ, Muoio DM, James DE (2017) Bicarbonate alters cellular responses in respiration assays. Biochem Biophys Res Commun 489:399-403.	LEAK OXPHOS	N NS	Permeabilized cells Intact cells	Mouse	Liver Fat
Sobotka 2017 Thesis	2017	Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127.	LEAK OXPHOS ET	F N NS	Homogenate Isolated mitochondria Intact cells	Mouse Rat	Liver
Nabeebaccus 2017 JCI Insight	2017	Nabeebaccus AA, Zoccarato A, Hafstad AD, Santos CX, Aasum E, Brewer AC, Zhang M, Beretta M, Yin X, West JA, Schröder K, Griffin JL, Eykyn TR, Abel ED, Mayr M, Shah AM (2017) Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. JCI Insight 2:96184.	LEAK ET	F N	Isolated mitochondria	Mouse	Heart
Buck 2017 PLOS ONE	2017	Buck E, Zügel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Human Mouse	Heart Skeletal muscle Nervous system Liver
Rowley 2017 J Nutr Biochem	2017	Rowley TJ, Bitner BF, Ray JD, Lathen DR, Smithson AT, Dallon BW, Plowman CJ, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O'Keefe SF, Neilson AP, Tessem JS (2017) Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. J Nutr Biochem 49:30-41.	OXPHOS ET	N S NS ROX	Permeabilized cells	Rat	Islet cell;pancreas;thymus
Fourcade 2017 Aging Cell	2017	Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A (2017) Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-13.	LEAK OXPHOS	N S NS ROX		Mouse
MacMillan 2017 Front Physiol	2017	MacMillan NJ, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe RT, Baril J, Carver TE, Andersen RE, Richard R, Perrault H, Bourbeau J, Hepple RT, Taivassalo T (2017) Eccentric ergometer training promotes locomotor muscle strength but not mitochondrial adaptation in patients with severe chronic obstructive pulmonary disease. Front Physiol 8:114.	OXPHOS	N CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Qi 2017 Ann Allergy Asthma Immunol	2017	Qi S, Cindy Barnig C, Charles AL, Poirot A, Meyer A, Clere-Jehl R, de Blay F, Geny B (2017) Nasal allergen challenge in allergic rhinitis induces mitochondrial dysfunction of peripheral blood mononuclear cells. Ann Allergy Asthma Immunol 118:367-9.	OXPHOS LEAK	N S CIV	Permeabilized cells	Human	Blood cells Lymphocyte
Zhang 2017 J Biol Chem	2017	Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES (2017) Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain. J Biol Chem 292:10239-49.	OXPHOS ET	N S	Permeabilized cells Homogenate	Human	Liver HEK
Rekuviene 2017 Neurosci Lett	2017	Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains. Neurosci Lett 653:45-50.		N S NS	Isolated mitochondria	Rat	Nervous system
Magnifico 2017 Oxid Med Cell Longev	2017	Magnifico MC, Oberkersch RE, Mollo A, Giambelli L, Grooten Y, Sarti P, Calabrese GC, Arese M (2017) VLDL induced modulation of nitric oxide signalling and cell redox homeostasis in HUVEC. Oxid Med Cell Longev 2017:2697364.	OXPHOS	N S CIV	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Yan 2017 BMC Genomics	2017	Yan X, Eynon N, Papadimitriou ID, Kuang J, Munson F, Tirosh O, O’Keefe L, Griffiths LR, Ashton KJ, Byrne N, Pitsiladis YP, Bishop DJ (2017) The gene SMART study: method, study design, and preliminary findings. BMC Genomics 18:821.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Edgett 2017 Thesis	2017	Edgett B (2017) Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in response to energetic stress in human skeletal muscle. Doctoral Dissertation p145.	LEAK OXPHOS	F N NS S	Permeabilized tissue	Human	Skeletal muscle
Dolezal 2017 J Biol Chem	2017	Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV (2017) Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem 292:10068-86.	LEAK OXPHOS	N S NS	Intact cells	Mouse	Liver
Buso 2017 Thesis	2017	Buso A (2017) Mitochondrial oxidative phosphorylation plasticity/adaptation triggered by disturbances and stresses and targeted by therapies. PhD Thesis p110.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Luethi 2017 Toxicology	2017	Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.	OXPHOS ET	NS N S DQ CIV ROX	Permeabilized cells	Human	Liver
Takahashi 2017 Exp Gerontol	2017	Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2017) Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria. Exp Gerontol 98:217-223.	OXPHOS	N	Isolated mitochondria	Mouse	Nervous system
Lalia 2017 Aging (Albany NY)	2017	Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129.	OXPHOS LEAK ET	F N NS ROX S	Isolated mitochondria	Human	Skeletal muscle
Djafarzadeh 2017b J Vis Exp	2017	Djafarzadeh S, Jakob SM (2017) Isolation of intact mitochondria from skeletal muscle by differential centrifugation for High-Resolution Respirometry measurements. J Vis Exp doi: 10.3791/55251.	LEAK OXPHOS	N S CIV NS	Isolated mitochondria		Skeletal muscle
Dent 2017 Mol Metab	2017	Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Vienne 2017 Anal Biochem	2017	Vienne JC, Cimetta C, Dubois M, Duburcq T, Favory R, Dessein AF, Fontaine M, Joncquel-Chevalier Curt M, Cuisset JM, Douillard C, Mention-Mulliez K, Dobbelaere D, Vamecq J (2017) A fast method for high resolution oxymetry study of skeletal muscle mitochondrial respiratory chain complexes. Anal Biochem 528:57-62.	LEAK OXPHOS ET	N CIV ROX S	Homogenate Permeabilized tissue	Pig	Skeletal muscle
Thomsen 2017 Neurobiol Aging	2017	Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M (2017) Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24.	LEAK OXPHOS	N NS ROX		Mouse	Nervous system
Gerber 2017 Brain	2017	Gerber S, Charif M, Chevrollier A, Chaumette T, Angebault C, Kane MS, Paris A, Alban J, Quiles M, Delettre C, Bonneau D, Procaccio V, Amati-Bonneau P, Reynier P, Leruez S, Calmon R, Boddaert N, Funalot B, Rio M, Bouccara D, Meunier I, Sesaki H, Kaplan J, Hamel CP, Rozet JM, Lenaers G (2017) Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effects on mitochondrial fusion and fission. Brain 140:2586-96.	LEAK OXPHOS ET	N S NS	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Haegler 2017 PLOS ONE	2017	Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026.	LEAK OXPHOS ET	N S CIV ROX DQ	Homogenate	Mouse	Liver
Jelenik 2017 Diabetes	2017	Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle Liver
Categories of SUIT protocols	2017	Gnaiger E (2017) Categories of SUIT protocols and ETS pathway control states. MiPNet 2017-03-12; original 2016-03-20; edited 2016-08-21.		F N S Gp CIV NS Other combinations ROX
Holland 2017 Placenta	2017	Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12.	LEAK ROUTINE OXPHOS	F N CIV NS ROX	Permeabilized cells Intact cells		Genital
Dechandt 2017 J Bioenerg Biomembr	2017	Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411.	LEAK ROUTINE ET	F N ROX	Permeabilized cells Intact cells	Rat	Liver
Chavanelle 2017 Sci Rep	2017	Chavanelle V, Boisseau N, Otero YF, Combaret L, Dardevet D, Montaurier C, Delcros G, Peltier SL, Sirvent P (2017) Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Sci Rep 7:204.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Zholobenko 2017 PLOS ONE	2017	Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691.	LEAK OXPHOS ET ROUTINE	F N S NS ROX	Permeabilized cells Intact cells	Rat	Heart
Dahlke 2017 Glob Chang Biol	2017	Dahlke FT, Leo E, Mark FC, Pörtner HO, Bickmeyer U, Frickenhaus S, Storch D (2017) Effects of ocean acidification increase embryonic sensitivity to thermal extremes in Atlantic cod, Gadus morhua. Glob Chang Biol 23(4):1499-1510.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Fishes
Wang 2017 J Am Heart Assoc	2017	Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Endothelial;epithelial;mesothelial cell
Shen 2017 Thesis	2017	Shen NY (2017) Characterizing protein arginine methyltransferase expression, localization, and function during myogenesis. Master's Thesis p106.	LEAK OXPHOS	N NS	Permeabilized cells	Mouse	Skeletal muscle
Chin 2017 US Patent	2017	Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1.	LEAK OXPHOS ET	N CIV ROX	Homogenate	Mouse	Heart
Trewin 2017 PLOS ONE	2017	Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H₂O₂ emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Geoghegan 2017 Oncol Lett	2017	Geoghegan F, Chadderton N, Farrar GJ, Zisterer DM1, Porter RK (2017) Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells. Oncol Lett 14:6298-306.		N NS ROX	Permeabilized cells	Human	Nervous system
Gruenig 2017 Toxicol In Vitro	2017	Grünig D, Felser A, Bouitbir J, Krähenbühl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria Permeabilized cells	Human Mouse	Liver Other cell lines
Ounpuu 2017 Biochim Biophys Acta	2017	Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54.	LEAK ROUTINE OXPHOS ET	N S NS ROX CIV	Permeabilized cells Intact cells	Human	Stem cells
Stepanova 2017 J Cereb Blood Flow Metab	2017	Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58.	OXPHOS ET LEAK	N NS ROX	Isolated mitochondria	Mouse	Nervous system
Klosterhoff 2017 Int J Biol Macromol	2017	Klosterhoff RR, Kanazawa LKS, Furlanetto ALDM, Peixoto JVC, Corso CR, Adami ER, Iacomini M, Fogaça RTH, Acco A, Cadena SMSC, Andreatini R, Cordeiro LMC (2017) Anti-fatigue activity of an arabinan-rich pectin from acerola (Malpighia emarginata). Int J Biol Macromol 109:1147-53.	OXPHOS	N ROX	Permeabilized tissue	Mouse	Skeletal muscle
Ljones 2017 PLOS ONE	2017	Ljones K, Ness HO, Solvang-Garten K, Gaustad SE, Andre Høydal M (2017) Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats. PLOS ONE 12:e0173449.	OXPHOS ET LEAK	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Zeidler 2017 J Biol Chem	2017	Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87.	LEAK ROUTINE ET	F N ROX	Intact cells	Mouse
Lemieux 2017 Sci Rep	2017	Lemieux H, Blier PU, Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Rep 7:2840. doi:10.1038/s41598-017-02789-8	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Mouse	Heart
Rekuviene 2017 Data Brief	2017	Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Data on effects of rotenone on calcium retention capacity, respiration and activities of respiratory chain complexes I and II in isolated rat brain mitochondria. Data Brief 13:707-12.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Nervous system
Krischek 2017 Animal	2017	Krischek C, Wimmers K, Janisch S, Wicke M, Sharifi AR (2017) Temperature alterations during embryogenesis have a sex-dependent influence on growth properties and muscle metabolism of day-old chicks and 35-day-old broilers. Animal 12:1224-31.	OXPHOS	N S		Birds	Skeletal muscle
Pravenec 2017 Physiol Res	2017	Pravenec M1, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Trnovská J, Škop V, Marková I, Malínská H, Hüttl M, Kazdová L, Bardová K, Tauchmannová K, Vrbacký M, Nůsková H, Mráček T, Kopecký J, Houštěk J (2017) Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity. Physiol Res 66:917-24.	OXPHOS	N NS	Isolated mitochondria	Rat	Endothelial;epithelial;mesothelial cell Fibroblast
Busanello 2017 Front Pharmacol	2017	Busanello ENB, Marques AC, Lander N, de Oliveira DN, Catharino RR, Oliveira HCF, Vercesi AE (2017) Pravastatin chronic treatment sensitizes hypercholesterolemic mice muscle to mitochondrial permeability transition: protection by creatine or coenzyme Q10. Front Pharmacol 8:185.	LEAK OXPHOS ET	N	Permeabilized tissue	Mouse	Skeletal muscle
Huang 2017 Sci Rep	2017	Huang L, Zhang K, Guo Y, Huang F, Yang K, Chen L, Huang K, Zhang F, Long Q, Yang Q (2017) Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts. Sci Rep 7:11989.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Carraro 2017 Mol Cell Endocrinol	2017	Carraro RS, Souza GF, Solon C, Razolli DS, Chausse B, Barbizan R, Victorio SC, Velloso LA (2017) Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol 460:238-45.	LEAK OXPHOS	N ROX	Permeabilized tissue	Mouse	Nervous system
Schreiber 2017 Cell Metab	2017	Schreiber R, Diwoky C, Schoiswohl G, Feiler U, Wongsiriroj N, Abdellatif M, Kolb D, Hoeks J, Kershaw EE, Sedej S, Schrauwen P, Haemmerle G, Zechner R (2017) Cold-induced thermogenesis depends on ATGL-mediated lipolysis in cardiac muscle, but not brown adipose tissue. Cell Metab 26:753-63.	LEAK	N Gp	Homogenate	Mouse	Fat
Jespersen 2017 J Physiol	2017	Jespersen NR, Yokota T, Støttrup NB, Bergdahl A, Paelestik KB, Povlsen JA, Dela F, Bøtker HE (2017) Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. J Physiol 595:3765-80.	LEAK OXPHOS	F N NS ROX S	Permeabilized tissue	Rat	Heart
Fink 2017 Am J Physiol Cell Physiol	2017	Fink BD, Bai F, Yu L, Sivitz WI (2017) Regulation of ATP production: dependence on calcium concentration and respiratory state. Am J Physiol Cell Physiol 313:C146-53.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Skeletal muscle
Perks 2017 Sci Adv	2017	Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A (2017) Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Heart Liver
Lau 2017 Dissertation	2017	Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Fishes	Nervous system
Porras 2017 Stem Cells	2017	Porras DP, Abbaszadeh M, Bhattacharya D, D'Souza NC, Edjiu NR, Perry CG, Scimè A (2017) p107 determines a metabolic checkpoint required for adipocyte lineage fates. Stem Cells 35:1378-91.	OXPHOS LEAK	F N	Intact cells	Mouse	Fat Fibroblast
Thaher 2017 Neurochem Int	2017	Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73.	LEAK ROUTINE OXPHOS ET	N NS ROX	Intact cells Permeabilized cells	Mouse	Fibroblast
Sharaf 2017 Biochim Biophys Acta	2017	Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse Fishes	Heart Liver
Lopez 2017 Sci Rep	2017	Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA (2017) Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. Sci Rep 7:9835.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells	Human
Cardinale 2017 Front Physiol	2017	Cardinale DA, Lilja M, Mandić M, Gustafsson T, Larsen FJ, Lundberg TR (2017) Resistance training with co-ingestion of anti-inflammatory drugs attenuates mitochondrial function. Front Physiol 8:1074.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Jeong 2017 Exp Mol Med	2017	Jeong JH, Cheol Kang Y, Piao Y, Kang S, Pak YK (2017) miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway. Exp Mol Med 49:e313.	OXPHOS	N S Gp CIV ROX	Permeabilized cells	Human	Liver
Asping 2017 Eur J Clin Pharmacol	2017	Asping M, Stride N, Søgaard D, Dohlmann TL, Helge JW, Dela F, Larsen S (2017) The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study. Eur J Clin Pharmacol 73:679-87.	LEAK ET	F N S CIV NS ROX	Permeabilized tissue	Human
Warren 2017 Metabolism	2017	Warren JL, Bulur S, Ovalle F, Windham ST, Gower BA, Fisher G (2017) Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women. Metabolism 77:1-12.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Kyhl 2017 Peptides	2017	Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12.	OXPHOS LEAK	F N S NS ROX	Permeabilized tissue	Rat	Heart
Wu 2017 Sci Rep	2017	Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191.	LEAK OXPHOS ET ROUTINE	N NS ROX CIV	Permeabilized cells Intact cells	Human	Blood cells Platelet
Cavalcanti-de-Albuquerque 2017 Mol Neurobiol	2017	Cavalcanti-de-Albuquerque JP, de Souza Ferreira E, de Carvalho DP, Galina A (2017) Mitochondria-bound hexokinase (mt-HK) activity differ in cortical and hypothalamic synaptosomes: differential role of mt-HK in H₂O₂ depuration. Mol Neurobiol 55:5889-5900.	LEAK OXPHOS	N S Gp ROX	Intact cells	Rat	Nervous system
Yang 2017 Cell Death Dis	2017	Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Saccharomyces cerevisiae Human	Lymphocyte
Jahandiez 2017 Basic Res Cardiol	2017	Jahandiez V, Cour M, Bochaton T, Abrial M, Loufouat J, Gharib A, Varennes A, Ovize M, Argaud L (2017) Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition. Basic Res Cardiol 112:35.	LEAK OXPHOS	N	Isolated mitochondria	Rabbit	Heart Nervous system
Merz 2017 Intensive Care Med Exp	2017	Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Mouse	Liver
Da Silva 2017 Neurotox Res	2017	Da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M (2017) α-Ketoadipic acid and α-aminoadipic acid cause disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90.	LEAK OXPHOS ET	N	Isolated mitochondria Homogenate	Rat	Nervous system
Da Silva 2017 Thesis	2017	da Silva LA (2017) Efeito do tratamento com N-acetilcisteína sobre dinâmica mitocondrial em modelo animal de isquemia crônica de membros inferiores. Dissertation p54.	OXPHOS	F N NS		Rat	Skeletal muscle
Tepp 2017 Mol Cell Biochem	2017	Tepp K, Puurand M, Timohhina N, Adamson J, Klepinin A, Truu L, Shevchuk I, Chekulayev V, Kaambre T (2017) Changes in the mitochondrial function and in the efficiency of energy transfer pathways during cardiomyocyte aging. Mol Cell Biochem 432:141-58.	OXPHOS LEAK	N S CIV ROX	Permeabilized cells	Rat	Heart
Kanaan 2017 Redox Biol	2017	Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME (2017) Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol 14:509-21.	LEAK OXPHOS	N CIV NS ROX	Permeabilized tissue	Mouse	Heart
Djafarzadeh 2017 J Vis Exp	2017	Djafarzadeh S, Jakob SM (2017) High-resolution respirometry to assess mitochondrial function in permeabilized and intact cells. J Vis Exp 8.doi: 10.3791/54985..	OXPHOS ET	N S CIV	Isolated mitochondria
Duicu 2017 Can J Physiol Pharmacol	2017	Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Heart
Cunha-de 2017 Thesis	2017	Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160.	LEAK ROUTINE OXPHOS ET	N NS ROX	Intact cells Permeabilized cells	Human	Liver Other cell lines
Wetzel 2017 Thesis	2017	Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125.	LEAK OXPHOS	F N NS ROX	Intact cells	Human	Fibroblast
Bal 2017 J Biol Chem	2017	Bal NC, Singh S, Reis FCG, Maurya SK, Pani S, Rowland LA, Periasamy M (2017) Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice. J Biol Chem 292:16616-25.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle Fat
Calcutt 2017 J Clin Invest	2017	Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22.	LEAK OXPHOS ET	N CIV ROX	Isolated mitochondria	Rat	Nervous system
Newsom 2017 Am J Physiol Endocrinol Metab	2017	Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Vigueira 2017 Exp Physiol	2017	Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN (2017) The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol 102:985-99.	OXPHOS LEAK	N	Permeabilized cells	Human	Kidney HEK
Tueller 2017 Biochem Biophys Res Commun	2017	Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72.	LEAK ROUTINE OXPHOS	F N NS ROX	Permeabilized cells Intact cells		Skeletal muscle
Cecatto 2017 Neurochem Int	2017	Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Nervous system Liver
Thomas 2017 Thesis	2017	Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells Intact cells	Rat	Liver
Koning 2017 J Cereb Blood Flow Metab	2017	Koning G, Leverin AL, Nair S, Schwendimann L, Ek J, Carlsson Y, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H (2017) Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection. J Cereb Blood Flow Metab 39:1038-55.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Rat
Liu 2017 Physiol Rep	2017	Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC (2017) Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiol Rep 5:e13157.	OXPHOS LEAK	F N	Isolated mitochondria	Rat	Heart
Testoni 2017 Cell Metab	2017	Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA6, Slebe F, Vilaseca M, Muñoz-Cánoves P, Guinovart JJ (2017) Lack of glycogenin causes glycogen accumulation and muscle function impairment. Cell Metab 26:256-66.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Warren 2017 J Nutr Metab	2017	Warren JL, Gower BA, Hunter GR, Windham ST, Moellering DR, Fisher G (2017) Associations of mitochondrial fatty acid oxidation with body fat in premenopausal women. J Nutr Metab 2017:7832057.	LEAK OXPHOS	F N	Permeabilized tissue	Human	Skeletal muscle
Asseburg 2017 Thesis	2017	Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse Rat	Nervous system Other cell lines
De Moura 2017 Neurotox Res	2017	de Moura Alvorcem L, da Rosa MS, Glänzel NM, Parmeggiani B, Grings M, Schmitz F, Wyse ATS, Wajner M, Leipnitz G (2017) Disruption of energy transfer and redox status by sulfite in hippocampus, striatum, and cerebellum of developing rats. Neurotox Res 32:264-75.	LEAK OXPHOS ET	N S NS	Homogenate	Rat	Nervous system
Ereminas 2017 Biomed Pharmacother	2017	Ereminas G, Majiene D, Sidlauskas K, Jakstas V, Ivanauskas L, Vaitiekaitis G, Liobikas J (2017) Neuroprotective properties of anthocyanidin glycosides against H₂O₂-induced glial cell death are modulated by their different stability and antioxidant activity in vitro. Biomed Pharmacother 94:188-96.	OXPHOS	N	Permeabilized cells	Rat	Nervous system
Cockova 2017 Thesis	2017	Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria	Human	Nervous system
De Carvalho 2017 Toxicol Research	2017	de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 .	LEAK OXPHOS ET	F N NS ROX S	Isolated mitochondria	Drosophila
Kake 2017 J Therm Biol	2017	Kake Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31.	LEAK OXPHOS	N CIV NS S ROX	Permeabilized tissue	Crustaceans
Keilhoff 2017 Brain Res	2017	Keilhoff G, Esser T, Titze M, Ebmeyer U, Schild L (2017) High-potential defense mechanisms of neocortex in a rat model of transient asphyxia induced cardiac arrest. Brain Res 1674:42-54.		N		Rat
Makrecka-Kuka 2017 Toxicol Lett	2017	Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Heart
Sharaf 2017 Aquat Toxicol	2017	Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83.	LEAK OXPHOS ET	ROX N	Isolated mitochondria	Fishes	Liver
Nan 2017 Circ Res	2017	Nan J, Hu H, Sun Y, Zhu L, Wang Y, Zhong Z, Zhao J, Zhang N, Wang Y, Wang Y, Ye J, Zhang L, Hu X, Zhu W, Wang J (2017) TNFR2 stimulation promotes mitochondrial fusion via Stat3- and NF-kB-dependent activation of OPA1 expression. Circ Res 121:392-410.	OXPHOS ET	N S NS ROX	Intact cells	Mouse	Heart
White 2017 Sci Rep	2017	White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Pamenter 2017 J Exp Biol	2017	Pamenter ME, Lau GY, Richards JG, Milsom WK (2017) Naked mole rat brain mitochondria electron transport system flux and H⁺ leak are reduced during acute hypoxia. J Exp Biol 221.	LEAK OXPHOS ET	N S CIV	Permeabilized cells	Other mammals	Nervous system
Anderson 2017 Cell Metab	2017	Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55.	OXPHOS LEAK	F N NS Other combinations	Isolated mitochondria	Mouse	Heart Liver
Parajuli 2017 PLOS ONE	2017	Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur JM, MacMillan-Crow LA (2017) Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLOS ONE 12:e0185542.	OXPHOS	N S ROX	Permeabilized tissue	Rat	Kidney
Schatton 2017 J Cell Biol	2017	Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017) CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-93.	LEAK OXPHOS ET	N NS	Intact cells Isolated mitochondria	Mouse	Liver
Varga 2017 Inflammopharmacology	2017	Varga G, Ugocsai M, Hartmann P, Lajkó N, Molnár R, Szűcs S, Jász DK, Érces D, Ghyczy M, Tóth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71.	OXPHOS LEAK	N S CIV NS ROX	Isolated mitochondria	Rat	Liver
Boudoures 2017 Thesis	2017	Boudoures AL (2017) Mitochondrial damage accumulation in oocytes – a potential link between maternal obesity and increased cardiometabolic disease risk in offspring. PhD Thesis p179.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Heart
Rowley 2017 Thesis	2017	Rowley TJ (2017) The effect of cocoa flavanols on β-cell mass and function. Master's Thesis p131.	OXPHOS ET	N NS ROX	Permeabilized cells	Rat	Islet cell;pancreas;thymus
Nabben 2017 Am J Physiol Regul Integr Comp Physiol	2017	Nabben M, Schmitz JP, Ciapaite J, Le Clercq CM, van Riel NA, Haak HR, Nicolay K, de Coo IF, Smeets HJ, Praet SF, van Loon LJ, Prompers JJ (2017) Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in mitochondrial myopathy patients. Am J Physiol Regul Integr Comp Physiol 312:689-701.	LEAK OXPHOS ET	F N S	Permeabilized tissue	Human	Skeletal muscle
Correa 2017 Crit Care	2017	Corrêa TD, Pereira AJ, Brandt S, Vuda M, Djafarzadeh S, Takala J, Jakob SM (2017) Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Crit Care 21:105.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Pig	Nervous system
Cardoso 2017 Biochim Biophys Acta	2017	Cardoso GMF, Pletsch JT, Parmeggiani B, Grings M, Glanzel NM, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2017) Bioenergetics dysfunction, mitochondrial permeability transition pore opening and lipid peroxidation induced by hydrogen sulfide as relevant pathomechanisms underlying the neurological dysfunction characteristic of ethylmalonic encephalopathy. Biochim Biophys Acta 1863:2192-2201.	LEAK OXPHOS ET	N S NS	Homogenate	Rat	Nervous system
Konopka 2017 J Appl Physiol (1985)	2017	Konopka AR, Castor WM, Wolff CA, Musci RV, Reid JJ, Laurin JL, Valenti ZJ, Hamilton KL, Miller BF (2017) Case studies in physiology: Skeletal muscle mitochondrial protein synthesis and respiration in response to the energetic stress of an ultra-endurance race. https://doi.org/10.1152/japplphysiol.00457.2017	OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Komlodi 2017 Neuropharmacology	2017	Komlódi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98.	LEAK OXPHOS ET	N S	Isolated mitochondria	Guinea pig	Nervous system
Volani 2017 Metallomics	2017	Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Liver
Wollenman 2017 PLOS ONE	2017	Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523.	LEAK OXPHOS ET	F N S NS	Isolated mitochondria	Guinea pig	Heart Liver
Balcaitis 2017 Thesis	2017	Balcaitis D (2017) The investigation of derivates of the 1,4-naphthoquinone effects to mitochondrial oxygen consumption in glioblastoma cells. Diploma Thesis p43.	OXPHOS	N NS		Rat	Nervous system Other cell lines
Boutant 2017 EMBO J	2017	Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58.	ROUTINE LEAK OXPHOS ET	ROX N S NS	Intact cells Homogenate Isolated mitochondria	Mouse	Fat Fibroblast
Bohanon 2017 Shock	2017	Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73.	LEAK OXPHOS ET	F N ROX	Intact cells	Mouse	Liver
Gusdon 2017 Exp Gerontol	2017	Gusdon AM, Callio J, Distefano G, O'Doherty RM, Goodpaster BH, Coen PM, Chu CT (2017) Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice. Exp Gerontol 90:1-13.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Nervous system
Linden 2016 Am J Physiol Gastrointest Liver Physiol	2017	Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95.	OXPHOS ET LEAK	N NS	Isolated mitochondria	Rat	Liver
Permer 2017 Bachelor Thesis	2017	Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Permeabilized cells Intact cells	Human	Other cell lines HEK
Xu 2017 Diabetes	2017	Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L (2017) RNA binding protein Ybx2 regulates RNA stability during cold-induced brown fat activation. Diabetes 66:2987-3000.	LEAK OXPHOS ET	N ROX		Mouse	Skeletal muscle
Rana 2017 Nat Commun	2017	Rana A, Oliveira MP, Khamoui AV, Aparicio R, Rera M, Rossiter HB, Walker DW (2017) Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster. https://doi.org/10.1038/s41467-017-00525-4	OXPHOS	N Gp NS		Drosophila
Mantilla 2017 PLOS Pathog	2017	Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158.	LEAK OXPHOS ET ROUTINE	S ROX N	Permeabilized cells Intact cells	Protists
Van Schaardenburgh 2017 J Transl Med	2017	van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Litt 2017 Thesis	2017	Litt MJ (2017) Identification and characterization of a cardiomyopathy syndrome resulting from loss of the melanocortin 4 receptor. Dissertation p172.	OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Heart
Ducker 2017 Cell Metab	2017	Ducker GS, Rabinowitz JD (2017) One-carbon metabolism in health and disease. Cell Metab 25:27-42.		N
Honrath 2017 Cell Death Differ	2017	Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM (2017) SK2 channels regulate mitochondrial respiration and mitochondrial Ca²⁺ uptake. Cell Death Differ 24:761-73.	LEAK OXPHOS ET	N	Isolated mitochondria	Mouse	Nervous system Other cell lines
MiPNet21.14 Reference sample HRR	2016-10-19	Development of a reference sample for HRR.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS Other combinations ROX	Intact cells Permeabilized cells	Human	HEK
MiPNet21.13 Comparison mt-preparations	2016-10-18	O2k-Protocols: Mitochondrial preparations for HRR.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Isolated mitochondria	Mouse	Heart
MiPNet21.12 Comparison mt respiration media	2016-10-18	O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	HEK
MiPNet21.07 MitoFit DatLab PT	2016-07-20	MitoFit DatLab proficiency test.	LEAK OXPHOS ET	F N S Gp CIV Other combinations ROX	Permeabilized cells	Human
Newell 2016 Physiol Entomol	2016	Newell C, Kane CL, Kane DC (2016) Mitochondrial substrate specificity in beetle flight muscle: assessing respiratory oxygen flux in small samples from Dermestes maculatus and Tenebrio molitor. Physiol Entomol p7.	OXPHOS	F N Gp Other combinations	Permeabilized tissue	Hexapods	Skeletal muscle
Bratic 2016 PLoS Genet	2016	Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A (2016) Mitochondrial polyadenylation is a one-step process required for mRNA integrity and tRNA maturation. PLoS Genet 12:e1006028.	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue	Drosophila
Porter 2016 Cell Metab	2016	Porter C, Herndon DN, Chondronikola M, Chao T, Annamalai P, Bhattarai N, Saraf MK, Capek KD, Reidy PT, Daquinag AC, Kolonin MG, Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS (2016) Human and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab 24:246-55.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human Mouse	Skeletal muscle Fat
Speijer 2016 Biochem J	2016	Speijer D (2016) Being right on Q: shaping eukaryotic evolution. Biochem J 473:4103-27.		F N ROX
Lark 2016 Am J Physiol Cell Physiol	2016	Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45.	LEAK OXPHOS ET	N Gp NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Farsijani 2016 J Clin Invest	2016	Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37.	LEAK OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Wuest 2016 Cardiovasc Res	2016	Wüst RC, de Vries HJ, Wintjes LT, Rodenburg RJ, Niessen HW, Stienen GJ (2016) Mitochondrial complex I dysfunction and altered NAD(P)H kinetics in rat myocardium in cardiac right ventricular hypertrophy and failure. Cardiovasc Res 111:362-72.	LEAK OXPHOS	N S	Intact cells Permeabilized tissue	Rat	Heart
Abdel-Rahman 2016 Oxid Med Cell Longev	2016	Abdel-Rahman EA, Mokhtar A, Aaliya A, Radwan Y, Yasseen B, Al-Okda A, Atwa A, Elhanafy E, Habashy M, Ali SS (2016) Resolving contributions of oxygen-consuming and ROS-generating enzymes at the synapse. Oxid Med Cell Longev p19.	LEAK OXPHOS	N NS ROX	Permeabilized cells	Mouse	Nervous system
Pesta 2016 FASEB J	2016	Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Bonifacio 2016 Arch Toxicol	2016	Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4	LEAK OXPHOS ET	N S DQ CIV NS	Permeabilized cells Permeabilized tissue Intact cells	Rat	Heart
Wang 2016 J Biol Chem	2016	Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51.	OXPHOS LEAK	N S NS	Homogenate	Mouse	Liver
Radovic 2016 Diabetologia	2016	Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016) Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia 59:1743-52.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Mouse	Liver
Kilbaugh 2016 Mitochondrion	2016	Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Witt 2016 Metab Brain Dis	2016	Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Vinnakota 2016a Biophys J	2016	Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA (2016) Feedback regulation and time hierarchy of oxidative phosphorylation in cardiac mitochondria. Biophys J 110:972-80.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Amaral 2016 Biochim Biophys Acta	2016	Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca²⁺ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Nervous system Liver
Chen 2016 Nat Chem Biol	2016	Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ (2016) Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol 12:937-43.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Human	HeLa
Gorbacheva 2016 International Symposium Mitochondrial Motility	2016	Gorbacheva OS, Strutynskyi RB, Khmil NV, Belosludtseva NV, Murzaeva SV, Korobeynikova MO, Alilova GA, Lezhnev EI, Mironova GD (2016) Study of the influence of flocalin on the energy and ion exchanges in rat liver mitochondria. International Symposium Mitochondrial Motility 73-7.	LEAK	F N S		Rat	Liver
Salin 2016 J Exp Biol	2016	Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62.	LEAK OXPHOS	N S CIV NS Other combinations ROX	Permeabilized tissue	Fishes	Skeletal muscle Liver
Gregg 2016 Diabetes	2016	Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced K_ATP channel activity. Diabetes 65:2700-10.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human Mouse	Islet cell;pancreas;thymus Other cell lines
Melenovsky 2016 Eur J Heart Fail	2016	Melenovsky V, Petrak J, Mracek T, Benes J, Borlaug BA, Nuskova H, Pluhacek T, Spatenka J, Kovalcikova J, Drahota Z, Kautzner J, Pirk J, Houstek J (2016) Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. Eur J Heart Fail 19:522-30.		N S	Homogenate	Human	Heart
Yamada 2016 J Physiol	2016	Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95.	LEAK OXPHOS	N S CIV Other combinations ROX		Mouse	Skeletal muscle Other cell lines
Karlsson 2016 Mitochondrion	2016	Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62.	ET	N ROX	Intact cells	Pig	Skeletal muscle Platelet
Scialo 2016 Cell Metab	2016	Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A (2016) Mitochondrial ROS produced via reverse electron transport extend animal lifespan. Cell Metab 23:725-34.	LEAK OXPHOS	N Gp CIV Other combinations ROX	Homogenate	Drosophila
Schoenenberger 2016 Cancer Res	2016	Schönenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36.	OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Nervous system
Gifford 2016 J Physiol	2016	Gifford JR, Garten RS, Nelson AD, Trinity JD, Layec G, Witman MA, Weavil JC, Mangum T, Hart C, Etheredge C, Jessop J, Bledsoe A, Morgan DE, Wray DW, Richardson RS (2016) Symmorphosis and skeletal muscle V_O₂max: in vivo and in vitro measures reveal differing constraints in the exercise-trained and untrained human. https://doi.org/10.1113/JP271229	OXPHOS	N NS	Permeabilized cells	Human	Skeletal muscle
Strifler 2016 Magyar Sebeszet	2016	Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8.	OXPHOS LEAK	N S CIV NS ROX Other combinations	Homogenate	Rat	Liver
Wolff 2016 J Evol Biol	2016	Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47.	LEAK OXPHOS ET	N Gp CIV Other combinations ROX	Permeabilized tissue	Drosophila	Skeletal muscle
Yavari 2016 Cell Metab	2016	Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of γ2 AMPK induces obesity and reduces β cell function. Cell Metab 23:821-36.	LEAK OXPHOS ET	N NS ROX	Homogenate	Mouse	Nervous system
Li 2016 Sci Rep	2016	Li N, Guenancia C, Rigal E, Hachet O, Chollet P, Desmoulins L, Leloup C, Rochette L, Vergely C (2016) Short-term moderate diet restriction in adulthood can reverse oxidative, cardiovascular and metabolic alterations induced by postnatal overfeeding in mice. Sci Rep 6:30817	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Heart
Briston 2016 Sci Rep	2016	Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Rat	Liver

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