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Difference between revisions of "Template:Current week ecosystem agenda"

From Bioblast
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  2020 Week 34
 
  2020 Week 35
* '''Aug-17 Mo''' 
 
* '''Aug-18 Tu'''


* '''Aug-24 Mo'''
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]
|'''Mitochondrial respiration in PBMCs from patients with major depression'''<br>
|'''Can NADH be directly used as substrate to obtain the NADH electron transfer-pathway state in high-resolution respirometry (HRR)? '''<br>
:from the O2k-Network »[[DE Ulm Karabatsiakis A]]« and »[[DE Ulm Radermacher P]]«
No, you cannot use NADH as a [[NADH Electron transfer-pathway state|NADH-linked]] substrate for [[Mitochondrial_respiration |mitochondrial respiration]] since the [[mitochondrial inner membrane]], which should be intact for HRR experiments, is not permeable to NADH. <br>
*Karabatsiakis A, Boeck C, Salinas-Manrique J, Kolassa S, Calzia E, Dietrich DE, Kolassa IT (2014) Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Transl Psychiatry 4:e397. [[Karabatsiakis 2014 Transl Psychiatry |»Bioblast link«]]
- »[[Nicotinamide_adenine_dinucleotide|Nicotinamide adenine dinucleotide]]« and »[[MitoPedia:_Substrates_and_metabolites|Substrates and metabolites]]«
|}
|}
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* '''Aug-25 Tu'''


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* '''Aug-19 We'''
* '''Aug-26 We'''  


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* '''Aug-20 Th'''
:{|
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
| Would you like to simultaneously monitor O<sub>2</sub> flux and the [[Q redox state|redox state]] of the [[Q-junction]] in isolated mitochondria? Soon you will be able to with the new Q-Module being developed as a part of the [[NextGen-O2k|H2020 SME NextGen-O2k]] project: <br>
| '''Non-mitochondrial respiration or [[residual oxygen consumption]] (''Rox'')? — Concept-driven constructive terminology frames our perception.'''
<br>
After inhibition of electron-transfer (ET) pathways or in the absence of fuel substrates, both ''mitochondrial'' non-ET reactions and ''non-mitochondrial'' reactions contribute to ''residual oxygen consumption'' in mt-preparations and living cells.  <br>
- »'''[[Q-Module]]'''«  
- »'''[https://www.bioenergetics-communications.org/index.php/BEC_2020.1_doi10.26124bec2020-0001.v1 BEC: Mitochondrial physiology]'''« — Table 1: ''Rox'' induced by non-ET pathway oxidation reactions
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|}
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* '''Aug-27 Th'''
::::* Notification to oral and poster presenters - »[[MitoEAGLE Summit Obergurgl 2020]]« (2020 Nov 04-07) and »[[MiPschool Obergurgl 2020]]« (2020 Nov 09-11)
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* '''Aug-21 Fr'''
* '''Aug-28 Fr'''

Revision as of 08:21, 24 August 2020

2020 Week 35
  • Aug-24 Mo
O2k-Open SupportWarning: loss of data Can NADH be directly used as substrate to obtain the NADH electron transfer-pathway state in high-resolution respirometry (HRR)?

No, you cannot use NADH as a NADH-linked substrate for mitochondrial respiration since the mitochondrial inner membrane, which should be intact for HRR experiments, is not permeable to NADH.
- »Nicotinamide adenine dinucleotide« and »Substrates and metabolites« 


  • Aug-25 Tu

  • Aug-26 We
MitoPedia
Non-mitochondrial respiration or residual oxygen consumption (Rox)? — Concept-driven constructive terminology frames our perception.

After inhibition of electron-transfer (ET) pathways or in the absence of fuel substrates, both mitochondrial non-ET reactions and non-mitochondrial reactions contribute to residual oxygen consumption in mt-preparations and living cells.
- »BEC: Mitochondrial physiology« — Table 1: Rox induced by non-ET pathway oxidation reactions


  • Aug-27 Th

  • Aug-28 Fr