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Difference between revisions of "Template:Current week ecosystem agenda"

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{{Template:Science for Ukraine}}
{{Template:Science for Ukraine}}
  2023 Week 45
  2024 Week 17


*'''Nov- 06 Mo'''
* '''Apr-22 Mo'''
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*'''Nov- 07 Tu'''
:{|
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
|'''How often should I re-assemble the O2k-chamber?'''<br>
|'''How can I evaluate the effect of one specific titration of a complex SUIT protocol?'''<br>
We recommend disassembling, cleaning and re-assembling the O2k-chamber at least every 1-2 years. It is also necessary to disassemble it when there is persistent biological or protein contamination, medium leakage from the chamber, an oxygen leak of the chamber, or an unstable or unexpectedly high or low oxygen signal.
Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.<br>
<br>
- »'''[[Flux control efficiency]]'''«, »'''[[Metabolic control variable]]'''«<br>
- »'''[https://wiki.oroboros.at/index.php/O2k-chamber#O2k-chamber_assembly_-_possible_problems O2k-chamber assembly - possible problems]'''« and »'''[https://www.youtube.com/watch?v=1MSsI1ePMu8&list=PLT4umseflf-m6O1sApyn9doi8vHNAKaIs&index=3 O2k-Videosupport: Insert O2k-chamber]'''«<br>
- communicated by »[[Cardoso Luiza]]« and »[[Baglivo Eleonora]]«  
- communicated by »[[Timon-Gomez Alba]]« and »[[Schmitt Sabine]]«
|}
|}
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*'''Nov- 08 We'''
* '''Apr-23 Tu'''  
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*'''Nov- 09 Th'''
* '''Apr-24 We'''  
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*'''Nov- 10 Fr'''
* '''Apr-25 Th'''
:{|
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
|''' When should I analyze my data as flux control ratios (''FCR''s)?'''<br>
|'''"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."''' <br>
''FCR''s enable the comparison of samples normalized with various mitochondrial content parameters or when sample concentration is unknown. This is achieved by internally normalizing O<sub><small>2</small></sub> fluxes in different respiratory states to the maximum flux in a common reference state. <br>
* Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. [[Meszaros_2024_Transpl_Int|»Bioblast link«]]
- »'''[[Flux control ratio]]'''« <br>
:from the O2k-Network »[[AT Innsbruck Schneeberger S]] and [[AT Innsbruck Oroboros]]«
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«  
|}  
|}
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* '''Apr-26 Fr'''
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'''<big>Next Week</big>'''
'''<big>Next Week</big>'''
2024 Week 18


2023 Week 46
* '''Apr-29 Mo'''
 
*'''Nov- 13 Mo'''
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*'''Nov- 14 Tu''' - World Diabetes Day
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|'''"Liver [mitochondria] (...) adapt to metabolic challenges by increasing FAO-derived mitochondrial respiration in OBES [obesity model] and NASH [non-alcoholic steatohepatitis model], but by increasing both FAO- and TCA-derived respiration in DIAB [diabetes model]."''' <br>
|'''How can I update DatLab 8 to the latest version?'''<br>
* Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. [[Dewidar 2023 EBioMedicine|»Bioblast link«]]
If your computer with DatLab 8 is connected to the internet, go to “Check for updates” in the Help menu of DatLab 8, and follow the simple installation instructions. <br>
:from the O2k-Network »[[DE Duesseldorf Roden M]]« and »[[DE Cologne Pesta D]]«
- »'''[[Updating - DatLab]]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ DatLab 8]'''«<br>
- communicated by »[[Leo Elettra]]« and »[[Baglivo Eleonora]]«
|}
|}
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*'''Nov- 15 We'''
* '''Apr-30 Tu'''  
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*'''Nov- 16 Th''' - World Pancreatic Cancer Day
* '''May-01 We'''   
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* '''May-02 Th'''  
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|'''"To the advantage of PDAC [pancreatic ductal adenocarcinoma] patients, innovative and more effective therapeutics will be possible with a greater understanding of how pancreatic cancer cells control mitochondrial metabolism."''' <br>
|''' "In respirometric studies on blood cells, the purity of cell preparation should always be emphasized and documented." '''<br>
* Padinharayil H, Rai V, George A (2023) Mitochondrial metabolism in pancreatic ductal adenocarcinoma: from mechanism-based perspectives to therapy. [[Padinharayil 2023 Cancers (Basel)|»Bioblast link«]]
- »'''[[MiPNet21.17 BloodCellsIsolation]]'''«<br>
- communicated by »[[Timon-Gomez Alba]]« and »[[Baglivo Eleonora]]«
|}
|}
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*'''Nov- 17 Fr'''
* '''May-03 Fr'''
---

Revision as of 08:23, 22 April 2024

Gentle Science
Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. -  »More details
A future for Ukraine is the future of its science
2024 Week 17
  • Apr-22 Mo
MitoPedia
How can I evaluate the effect of one specific titration of a complex SUIT protocol?

Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.
- »Flux control efficiency«, »Metabolic control variable«
- communicated by »Cardoso Luiza« and »Baglivo Eleonora« 


  • Apr-23 Tu

  • Apr-24 We

  • Apr-25 Th
O2k-Publications in the MiPMap "Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."
  • Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. »Bioblast link«
from the O2k-Network »AT Innsbruck Schneeberger S and AT Innsbruck Oroboros«

  • Apr-26 Fr

Next Week

2024 Week 18
  • Apr-29 Mo
O2k-Open SupportInfo: improve How can I update DatLab 8 to the latest version?

If your computer with DatLab 8 is connected to the internet, go to “Check for updates” in the Help menu of DatLab 8, and follow the simple installation instructions.
- »Updating - DatLab«, »DatLab 8«
- communicated by »Leo Elettra« and »Baglivo Eleonora«


  • Apr-30 Tu

  • May-01 We

  • May-02 Th
O2k-Open SupportInfo: improve "In respirometric studies on blood cells, the purity of cell preparation should always be emphasized and documented."

- »MiPNet21.17 BloodCellsIsolation«
- communicated by »Timon-Gomez Alba« and »Baglivo Eleonora«


  • May-03 Fr