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2020 Week 35
- Aug-24 Mo
Can NADH be directly used as substrate to obtain the NADH electron transfer-pathway state in high-resolution respirometry (HRR)?
No, you cannot use NADH as a NADH-linked substrate for mitochondrial respiration since the mitochondrial inner membrane, which should be intact for HRR experiments, is not permeable to NADH.
- »Nicotinamide adenine dinucleotide« and »Substrates and metabolites«
- Aug-25 Tu
- Aug-26 We
Non-mitochondrial respiration or residual oxygen consumption (Rox)? — Concept-driven constructive terminology frames our perception. After inhibition of electron-transfer (ET) pathways or in the absence of fuel substrates, both mitochondrial non-ET reactions and non-mitochondrial reactions contribute to residual oxygen consumption in mt-preparations and living cells.
- »BEC: Mitochondrial physiology« — Table 1: Rox induced by non-ET pathway oxidation reactions
- Aug-27 Th
- Aug-28 Fr
