MiPschool Obergurgl 2017

MiPschool Obergurgl 2017

Obergurgl AT, 2017 Jul 23-30. 10^th MiPschool 2017 MitoEAGLE and MitoEAGLE Workshop WG1-4.

Mitochondrial Physiology Society (2017-07-23) MitoGlobal

Abstract: 2017 Jul 23-30, Obergurgl, AT.

Labels:

2017, ORO, MitoFit, MitoEAGLE, MiP, TRACT, MitoGlobal

News

Joint terminology review: open for contributions and feedback

[|Building blocks of mitochondrial physiology]

Date, venue, organization

2017 July 23-30

2017 July 23-27 Training School jointly organized by the Mitochondrial Physiology Society and COST Action MitoEAGLE
2017 July 27-30 MitoEAGLE Workshop: WG1-4

University Centre Obergurgl, Tyrol, Austria

Minutes MitoAGLE Obergurgl 2017

- Minutes prepared by Zuzana Sumbalova.

Find the WG summaries in the Minutes and also here

Feedback

Congratulations on a very successful MiPschool in Obergurgl. The organization was excellent. I'm very happy that I could participate in this event. It has been an amazing time, full of great presentations and exciting discussions. I have learned a lot and I think it will bring benefits in my future work. So one more time, great thanks to you and your team. - Karolina Siewiera, Lodz, PL

It was really a pleasure to be a part of such a great group of people and it gave me a motivation in my work. I enjoyed all presentations which were very interesting and brought new insight into the problematics but especially like the small table sessions with experts. Next thing that I will remember for a long time was working with you and Chuck and Javier and everybody else who participated on writing the common review on mitochondrial terminology. I have never seen such a professionality and group spirit during the manuscript preparation and I like it a lot. Those moments were very fascinating and completely absorbing. - Ondrej Sobotka, Hradec Kralova, CZ

It was another enjoyable and productive meeting. I am delighted to be a part of this team. My new students have returned from MIPSchool energized and motivated to work on their projects. - Anthony Molina, Winston-Salem, North Carolina, US.
The 10th MiPschool and the MitoEAGLE workshop in Obergurgl were an amazingly enriching experience for me. Having just recently started working in mitochondrial physiology, these meetings provided critical insight of what are the state-of-the-art techniques and questions related to mitochondria. The program is balanced, although there is certainly space for improvement. And that is a positive thing. I would also like to emphasize that the sense of scientific community built on sharing knowledge and sheer friendship that allowed me to set new, hopefully long and fruitful collaborations. - Luís Crisóstomo, MSc, PhD Student, Porto, PT.

Thanks a lot, has been an amazing meeting. I have learnt a lot and I have enjoyed each minute spent in the beautiful Obergurgl. Also, working with you (Erich Gnaiger) and with Charles (Hoppel) has been an amazing opportunity to learn and grow as a scientist. - Javier Iglesias-González, PhD, Manchester, UK.

I just wanted to congratulate and thank you for the exciting and productive MitoEAGLE event. - Brian Irving, PhD, Baton Rouge, La, US

I would just like to say thank you for the effort and expertise that you brought in this MiP School. I have learned so much from your training that will assist me in my workplace. Thank you very much for your presentation in Oxygraph. For me, it stands out as one of the best training school I have been to. I have come away with much more knowledge and feel far more equipped to deal with related to mitochondrial research issues. It was lovely to meet you and all the other participants within such a great learning environment. Thank you again such an informative and entertaining days of learning. Now, I am able to walk with a new understanding of and strategies in, dealing in research. - Vipin Sharma, Ahemdabad, IN

Thank you once again for a wonderful meeting! Although I was a bit unwell during portions of the meeting, I enjoyed all the discussions and camaraderie. I have attached some pictures that Raj and I captured during the meeting. We also look forward to many photos/videos taken during the meeting as well. Hope to see you all soon. - Shilpa Iyer, Fayetteville , AR, US

I am very grateful for having an opportunity to be present at 10th MiPschool and the MitoEAGLE workshop in Obergurgl. For me as a beginner it was great chance to learn a lot about mitochondrial topic, especially those terminology sessions were very enriching. Last but not least, I have met a lot of wonderful people, who are inspiriting and I was my greatest pleasure to spend this time with them. Thank you very much. - Katerina Nozickova, Hradec Kralove, CZ

Programme MiPschool

The MiPschool will focus on basic concepts on mitochondrial respiratory states and applications of substrate-uncoupler-inhibitor titration (SUIT) protocols. - Last update: 2017-07-22

- - - 2017-07-23

Arrival MiPschool

16:00 Registration

18:30 Joint dinner

20:30 - 21:30 Welcome by the organizers Verena Laner - General Secretary MiPsociety and Erich Gnaiger - Chair COST Action MitoEAGLE

- - - 2017-07-24

Session A (morning) Coupling and pathway control in oxidative phosphorylation

08:30-09:10

Elemental steps towards understanding mitochondrial core energy metabolism: coupling control (Erich Gnaiger, Medical University of Innsbruck, AT).

09:10-09:40

Biochemical coupling efficiency and ATP/O₂ ratios (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).

09:40-10:00 Selected oral presentations A.1-2

10:00-10:30 Coffee/tea break - poster viewing

10:30-11:10

The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen (Anthony L Moore, University of Sussex, UK).

11:10-11:40

Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology (Gnaiger Erich, Medical University of Innsbruck, AT).

11:40-12:00 Selected oral presentations A.3-4

	Presentation	Session
Meszaros 2017 MiPschool Obergurgl	(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.	A1 Oral
Hellgren 2017 MiPschool Obergurgl	Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production.	A1 Oral
Sobotka 2017 MiPschool Obergurgl	Reference protocols for ROS production measurements.	A1 Oral
Komlodi 2017 MiPschool Obergurgl	Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H₂O₂ production.	A1 Oral
Gnaiger 2017 MiPschool A1	Elemental steps towards understanding mitochondrial core energy metabolism: coupling control.	A1 Review
Gnaiger 2017 MiPschool A4	Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology.	A1 Review
Moore 2017 MiPschool Obergurgl	The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen.	A1 Review
Hoppel 2017 MiPschool Obergurgl A	Biochemical coupling efficiency and ATP/O₂ ratios.	A1 Review

13:00-15:00 Walk&Talk, Run&Fun, Person-to-person poster talks or MIGHT!TM game time

Session B (afternoon) selected abstracts/posters

B1: ROS signaling, oxidative stress, cancer

15:00-15:20 Selected oral presentations B1.1-2

15:20-16:00 Poster session and general discussion

16:00-16:30 Coffee/tea - Poster session continued

	Presentation	Session
Gainutdinov 2017 MiPschool Obergurgl	Different ways of reactive oxygen species (ROS) formation by brain mitochondria.	B1 Poster
Silkuniene 2017 MiPschool Obergurgl	Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment.	B1 Oral
Gasparrini 2017 MiPschool Obergurgl	Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS.	B1 Poster
Giampieri 2017 MiPschool Obergurgl	Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality.	B1 Poster
Afrin 2017 MiPschool Obergurgl	Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism.	B1 Poster
Brown 2017 MiPschool Obergurgl	Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain.	B1 Oral
Iglesias-Gonzalez 2017 MiPschool Obergurgl	Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.	B1
Karavyraki 2017 MiPschool Obergurgl	Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.	B1
Hoel 2017 MiPschool Obergurgl	A study on mitochondrial stress responses due to OXPHOS inhibition.	B1

B2: Life style, degenerative and mitochondrial diseases

16:30-17:30 Selected oral presentations B2.1-6

17:30-18:30 Poster session and general discussion

	Presentation	Session
Amick 2017 MiPschool Obergurgl	Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.	Oral B2
Collins 2017 MiPschool Obergurgl	The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics.	B2 Oral
Ene 2017 MiPschool Obergurgl	Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo.	B2 Oral
Isola 2017 MiPschool Obergurgl	Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies?	B2 Oral
Sharma 2017 MiPschool Obergurgl	Role of ATP-sensitive potassium (K_ATP) and maxi potassium (BK_Ca) channels in beta₃-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis).	B2 Poster
Soares 2017 MiPschool Obergurgl	Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy.	B2 Oral
Distefano 2017 MiPschool Obergurgl	Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects.	B2 Oral
Krylova 2017 MiPschool Obergurgl	High-resolution respirometry in diagnostic of mitochondrial complex I deficiency.	B2 Poster
Crisostomo 2017 MiPschool Obergurgl	Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.	B2 Poster
Pavlovic 2017 MiPschool Obergurgl	Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.	B2

18:30 Dinner

After dinner interplay: Anthony L Moore and Erich Gnaiger discuss perspectives on the Q-junction, inviting interactions with the audience.

- - - 2017-07-25

Session C (morning) OXPHOS protocols and data reporting

08:30-09:10

Apparent Complex IV excess capacity and biochemical thresholds (Gnaiger Erich, Medical University of Innsbruck, AT).

09:10-09:40

Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles (Carolina Doerrier, Oroboros Instruments, AT).

09:40-10:00 Selected oral presentations C.1-2

10:00-10:30 Coffee/tea break - poster viewing

10:30-11:10

Respiratory control ratios and control factors (Gnaiger Erich, Medical University of Innsbruck, AT).

11:10-11:40

Discussion: Normalization of respiratory flux and flow.

11:40-11:50 Selected oral presentations C.3-4

	Presentation	Session
Nogueras 2017 MiPschool Obergurgl	Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients.	C1 Oral
Siewiera 2017 MiPschool Obergurgl	Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.	C1 Oral
Garcia-Souza 2017 MiPschool Obergurgl	Assessment of mitochondrial respiratory function in cryopreserved platelets.	C1 Oral
Keppner 2017 MiPschool Obergurgl	Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.	C1 Oral
Gnaiger 2017 MiPschool C1	Apparent Complex IV excess capacity and biochemical thresholds.	Review C1
Doerrier 2017 MiPschool C2	Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.	C1 Review
Gnaiger 2017 MiPschool C4	Respiratory control ratios and control factors	Review C1

13:00-15:00 Walk & Talks, Run & Fun, Person-to-person poster talks or MIGHT!TM game time

Session D (afternoon) Posters and selected abstracts

D1. Models and mt-preparations in mitochondrial physiology

15:00-16:00 Selected oral presentations D1.1-6

16:00-16:30 Coffee/tea - poster viewing

	Presentation	Session
Iyer 2017b MiPschool Obergurgl	Patient-specific stem cell models for mitochondrial diseases.	D1 Oral
Juhasz 2017 MiPschool Obergurgl	Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.	D1 Oral
McKenna 2017 MiPschool Obergurgl	A systematic review of the use of respirometry in critically ill patients.	D1 Oral
Markova 2017 MiPschool Obergurgl	Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase.	D1 Oral
Bento 2017 MiPschool Obergurgl	Isolation of human urine-derived stem cells for mitochondrial function profile assessment.	D1
Krajcova 2017 MiPschool Obergurgl	Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.	D1
Rao 2017 MiPSchool Obergurgl	Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl	D1
Petit 2017 MiPschool Obergurgl	Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence.	Oral D1
Holzknecht 2017 MiPschool Obergurgl	Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook.	Oral D1

D2. Pharmacological intervention, toxicology, and regulation

16:30-17:10 Selected oral presentations D2.1-4

17:10-18:00 Poster session and general discussion

18:00 Dinner

	Presentation	Session
Dias 2017 MiPschool Obergurgl	Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells.	D2 Oral
Bernardino 2017 MiPschool Obergurgl	Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition.	D2 Oral
Varela-Lopez 2017 MiPschool Obergurgl	Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats.	D2 Poster
Forbes-Hernandez 2017 MiPschool Obergurgl	The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect?	D2 Poster
Baraldo 2017 MiPschool Obergurgl	Fahd-1 links metabolism and neuronal activity in C. elegans.	D2 Oral
Reboredo-Rodriguez 2017 MiPschool Obergurgl	Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line.	D2 Poster
Liebscher 2017 MiPschool Obergurgl	The LAMTOR complex in regulation of fat metabolism.	D2 Oral
Ferreira 2017 MiPschool Obergurgl	Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.	D2

20:00-21:30

Session D3 MitoEAGLE Early Career Investigators forum (organized by Komlòdi Timea, Oroboros Instruments, Innsbruck, AT; and Garcia e Souza Luiz, University Innsbruck, AT): Meet the expert

- - - 2017-07-26

Session E1 (morning) Clinical mitochondrial physiology

08:30-09:00

The challenges of functional mitochondrial diagnosis (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).

09:00-09:30

Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).

09:30-10:00

Scope and limitations of functional mitochondrial diagnosis in blood cells. (Anthony Molina,Department of Internal Medicine, US).

10:00-10:30 Coffee/tea break

10:30-11:00

The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. (Beata Cizmarova, Pavol Jozef Šafárik University in Kosice, SK)

11:00-11:30

Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives (Anthony L Moore, University of Sussex, UK).

11:30-12:00

Pyruvate therapy for mitochondrial diseases (Masashi Tanaka, Tokyo Metropolitan Institute of Gerontology, JP).

	Presentation	Session
Tanaka 2017 MiPschool Obergurgl	Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation.	E1 Review
Garcia-Roves 2017 MiPschool Obergurgl	Mitochondrial fitness in skeletal muscle.	E1 Review
Hoppel 2017 MiPschool Obergurgl E1	The challenges of functional mitochondrial diagnosis.	E1 Review
Cizmarova 2017 MiPschool Obergurgl	The scope of cryopreservation in blood cells for functional mitochondrial diagnosis.	E1 Review
Molina 2017 MiPschool Obergurgl	Scope and limitations of functional mitochondrial diagnosis in blood cells.	E1
Moore 2017 MiPschool Obergurgl E1	Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives.	E1 Review

13:00-15:00 Walk&Talks, Run&Fun, Person-to-person poster talks, MIGHT!TM game time

Session E2 (afternoon) Mitochondrial physiology: biomedical applications

15:00-15:30

Mitochondrial function and dysfunction: ROS and Ca²⁺. (Werner Koopman, Radboud University Nijmegen Medical Centre, NL)

15:30-16:00

Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).

16:00-16:30 Coffee/tea

16:30-17:00

The metabolic syndrome - dysmitochondrial syndrome and mitochondrial disruptors (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).

17:00-17:30

Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).

	Presentation	Session
Jansen-Duerr 2017 MiPschool Obergurgl	Role of mitochondria in ageing and regeneration.	E2 Review
Koopman 2017 MiPschool Obergurgl	Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation	E2 Review
Lee 2017 MiPschool Obergurgl	The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation	E2 Review
Porter 2017 MiPschool Obergurgl	Mitochondrial function and dysfunction in cancer.	E2

18:30 Dinner

20:00 Conclusion and social programme with Raphael

- - - 2017-07-27

Departure MiPschool

Relaxing day for participants staying for the MitoEAGLE WG Workshop

Lecturers

Programme MitoEAGLE Working Groups Workshop

- - - 2017-07-27

Arrival MitoEAGLE workshop

- - - 2017-07-28 to 29

MitoEAGLE Workshop: WG1-4

WG1: Harmonization of nomenclature on mitochondrial respiratory states and control parameters: Status of the consensus paper on a consistent terminology on mitochondrial physiology and bioenergetics; recommendations for the use of a common terminology in mitochondrial physiological research as a milestone towards unification of concepts and nomenclature.

» The protonmotive force and respiratory control: Building blocks of mitochondrial physiology - Manuscript in preparation by the MitoEAGLE Terminology Group.

» Add critical discussion on 'ATP production' (not to be confused with a difference of respiratory fluxes), 'glycolytic flux' (not to be confused with extracellular proton flux), 'reserve capacity' (is the difference of ET capacity and ROUTINE respiratory activity a 'reserve'?), confusion of ET capacity ('State 3u') and OXPHOS capacity, ..

WG1: Respirometric reference protocols:

Standard format for presenting substrate-uncoupler-inhibitor titration (SUIT) protocols for a ‘library of protocols’ applied in mitochondrial respiratory physiology.
Criteria for selecting and recommending reference protocols.
Documentation of the state-of-the-art standards in designing, conducting, reporting, interpreting, and validating SUIT protocols.
Compare: Maelstrom Research program- data repository and harmonization.

WG2-4: Data repositories

Summary of WG2: steps towards database: Summary from Obergurgl, 2017.
Summary of WG4 cell lines: WG4 Cell Lines Obergurgl, 2017.
Summary of WG4 blood cells:WG4 Blood cells Obergurgl, 2017

- - - 2017-07-30

Departure MitoEAGLE

	Presentation	MiP areas	Mammals;models	Tissues;cells	Stress conditions	Pathological states	Session
Krajcova 2017 MITOEAGLE Obergurgl	Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.	Respiration Pharmacology;toxicology	Human			Cardiovascular	A1 Oral
Chabi 2017 MITOEAGLE Obergurgl	Optimization of permeabilized fibers preparation for mitochondrial respiration measurements using Design of Experiments methodology.	Respiration	Mouse	Skeletal muscle			A1 Poster
Pavlovic 2017 MITOEAGLE Obergurgl	Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.	Respiration mt-Medicine mt-Awareness	Mouse	Skeletal muscle		Diabetes	A1 Oral
Gainutdinov 2017 MITOEAGLE Obergurgl	Different ways of reactive oxygen species (ROS) formation by brain mitochondria.	Respiration	Mouse Rat	Nervous system	Oxidative stress;RONS		A1 Oral
Ukropec 2017 MITOEAGLE Obergurgl	Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment?	Respiration Exercise physiology;nutrition;life style		Skeletal muscle		Aging;senescence Diabetes Neurodegenerative	A1 Oral
Bento 2017 MITOEAGLE Obergurgl	Isolation of human urine-derived stem cells for mitochondrial function profile assessment.	Respiration	Human	Stem cells			A1 Oral
Ferreira 2017 MITOEAGLE Obergurgl	Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.	Pharmacology;toxicology Respiration	Mouse	Heart Stem cells			A1 Oral
Waldauf 2017 MITOEAGLE Obergurgl	Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates.	Respiration Pharmacology;toxicology	Human	Skeletal muscle			A1 Oral
Garcia-Roves 2017 MITOEAGLE Obergurgl	MitoEAGLE data repository on muscle tissues - current status.						A1 Oral
Muntane 2017 MITOEAGLE Obergurgl	Integration of oxidative and nitrosative stress in the overall cell death signaling induced by Sorafenib in hepatoma cells.	Pharmacology;toxicology	Human	Liver	Cell death Oxidative stress;RONS	Cancer	A1 Oral
Dubouchaud 2017 MITOEAGLE Obergurgl	Effects of a single bout of exercise on the production of reactive oxygen species in muscle and liver isolated mitochondria.	Exercise physiology;nutrition;life style Respiration	Rat	Skeletal muscle Liver	Oxidative stress;RONS		A1 Oral
Crisostomo 2017 MITOEAGLE Obergurgl	Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.		Human	Genital			A1 Oral Poster
Iglesias-Gonzalez 2017 MITOEAGLE Obergurgl	Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.	Respiration mt-Medicine			Oxidative stress;RONS		A1 Oral
Scatena 2017 MITOEAGLE Obergurgl	Cancer stem cell differentiation induced by PPAR ligands. Which role for an inhibition of mitochondrial respiratory chain?	Pharmacology;toxicology	Human	Liver		Cancer	A1 Poster

Participants - alphabetical order

(Attendance list)

	Presentation	Session
Afrin 2017 MiPschool Obergurgl	Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism.	B1 Poster
Amick 2017 MiPschool Obergurgl	Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.	Oral B2
Ashcroft 2017 MiPschool Obergurgl	No abstract.
Baraldo 2017 MiPschool Obergurgl	Fahd-1 links metabolism and neuronal activity in C. elegans.	D2 Oral
Bekebrede 2017 MiPschool Obergurgl	No abstract.
Bento 2017 MiPschool Obergurgl	Isolation of human urine-derived stem cells for mitochondrial function profile assessment.	D1
Bernardino 2017 MiPschool Obergurgl	Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition.	D2 Oral
Bezuidenhout 2017 MiPschool Obergurgl	No abstract.
Brown 2017 MiPschool Obergurgl	Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain.	B1 Oral
Cizmarova 2017 MiPschool Obergurgl	The scope of cryopreservation in blood cells for functional mitochondrial diagnosis.	E1 Review
Collins 2017 MiPschool Obergurgl	The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics.	B2 Oral
Crisostomo 2017 MiPschool Obergurgl	Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.	B2 Poster
Di Nolfo 2017 MiPschool Obergurgl	Middle cerebral artery modification in mouse model of Marfan Syndrom and potential role of Nox4.
Dias 2017 MiPschool Obergurgl	Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells.	D2 Oral
Distefano 2017 MiPschool Obergurgl	Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects.	B2 Oral
Doerrier 2017 MiPschool C2	Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.	C1 Review
Ene 2017 MiPschool Obergurgl	Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo.	B2 Oral
Ferreira 2017 MiPschool Obergurgl	Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.	D2
Forbes-Hernandez 2017 MiPschool Obergurgl	The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect?	D2 Poster
Gainutdinov 2017 MiPschool Obergurgl	Different ways of reactive oxygen species (ROS) formation by brain mitochondria.	B1 Poster
Garcia-Roves 2017 MiPschool Obergurgl	Mitochondrial fitness in skeletal muscle.	E1 Review
Garcia-Souza 2017 MiPschool Obergurgl	Assessment of mitochondrial respiratory function in cryopreserved platelets.	C1 Oral
Gasparrini 2017 MiPschool Obergurgl	Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS.	B1 Poster
Gerna 2017 MiPschool Obergurgl	No abstract.
Ghanim 2017 MiPschool Obergurgl	HAMLET derivatives as a pre-operative therapy in oesophageal cancer.
Giampieri 2017 MiPschool Obergurgl	Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality.	B1 Poster
Gnaiger 2017 MiPschool A1	Elemental steps towards understanding mitochondrial core energy metabolism: coupling control.	A1 Review
Gnaiger 2017 MiPschool A4	Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology.	A1 Review
Gnaiger 2017 MiPschool C1	Apparent Complex IV excess capacity and biochemical thresholds.	Review C1
Gnaiger 2017 MiPschool C4	Respiratory control ratios and control factors	Review C1
Hellgren 2017 MiPschool Obergurgl	Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production.	A1 Oral
Hoel 2017 MiPschool Obergurgl	A study on mitochondrial stress responses due to OXPHOS inhibition.	B1
Holzknecht 2017 MiPschool Obergurgl	Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook.	Oral D1
Hoppel 2017 MiPschool Obergurgl A	Biochemical coupling efficiency and ATP/O₂ ratios.	A1 Review
Hoppel 2017 MiPschool Obergurgl E1	The challenges of functional mitochondrial diagnosis.	E1 Review
Iglesias-Gonzalez 2017 MiPschool Obergurgl	Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.	B1
Irving 2017 MiPSchool Obergurgl	No abstract.
Isola 2017 MiPschool Obergurgl	Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies?	B2 Oral
Iyer 2017a MiPschool Obergurgl	A science-based strategy game for understanding mitochondrial bioenergetics.
Iyer 2017b MiPschool Obergurgl	Patient-specific stem cell models for mitochondrial diseases.	D1 Oral
Jansen-Duerr 2017 MiPschool Obergurgl	Role of mitochondria in ageing and regeneration.	E2 Review
Juhasz 2017 MiPschool Obergurgl	Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.	D1 Oral
Kamel 2017 MiPschool Obergurgl	No abstract.
Karavyraki 2017 MiPschool Obergurgl	Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.	B1
Keppner 2017 MiPschool Obergurgl	Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.	C1 Oral
Komlodi 2017 MiPschool Obergurgl	Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H₂O₂ production.	A1 Oral
Koopman 2017 MiPschool Obergurgl	Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation	E2 Review
Krajcova 2017 MiPschool Obergurgl	Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.	D1
Krylova 2017 MiPschool Obergurgl	High-resolution respirometry in diagnostic of mitochondrial complex I deficiency.	B2 Poster
Lee 2017 MiPschool Obergurgl	The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation	E2 Review
Liebscher 2017 MiPschool Obergurgl	The LAMTOR complex in regulation of fat metabolism.	D2 Oral
Markova 2017 MiPschool Obergurgl	Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase.	D1 Oral
McKenna 2017 MiPschool Obergurgl	A systematic review of the use of respirometry in critically ill patients.	D1 Oral
Meszaros 2017 MiPschool Obergurgl	(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.	A1 Oral
Molina 2017 MiPschool Obergurgl	Scope and limitations of functional mitochondrial diagnosis in blood cells.	E1
Moore 2017 MiPschool Obergurgl	The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen.	A1 Review
Moore 2017 MiPschool Obergurgl E1	Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives.	E1 Review
Nogueras 2017 MiPschool Obergurgl	Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients.	C1 Oral
Nozickova 2017 MiPschool Obergurgl	Sulfite oxidase.
Pavlovic 2017 MiPschool Obergurgl	Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.	B2
Petit 2017 MiPschool Obergurgl	Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence.	Oral D1
Porter 2017 MiPschool Obergurgl	Mitochondrial function and dysfunction in cancer.	E2
Pranger 2017 MiPschool Obergurgl	No abstract.
Rao 2017 MiPSchool Obergurgl	Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl	D1
Reboredo-Rodriguez 2017 MiPschool Obergurgl	Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line.	D2 Poster
Salti 2017 MiPschool Obergurgl	No abstract.
Schartner 2017 MiPschool Obergurgl	No abstract.
Schoepp 2017 MiPschool Obergurgl	Generation and characterization of human cardiomyocytes obtained from iPSCs derived from patients with Friedreich’s ataxia.
Sharma 2017 MiPschool Obergurgl	Role of ATP-sensitive potassium (K_ATP) and maxi potassium (BK_Ca) channels in beta₃-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis).	B2 Poster
Shi 2017 MiPschool Obergurgl	No abstract.
Siewiera 2017 MiPschool Obergurgl	Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.	C1 Oral
Silkuniene 2017 MiPschool Obergurgl	Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment.	B1 Oral
Soares 2017 MiPschool Obergurgl	Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy.	B2 Oral
Sobotka 2017 MiPschool Obergurgl	Reference protocols for ROS production measurements.	A1 Oral
Stevens 2017 MiPschool Obergurgl	No abstract.
Tanaka 2017 MiPschool Obergurgl	Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation.	E1 Review
Varela-Lopez 2017 MiPschool Obergurgl	Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats.	D2 Poster
Venz 2017 MiPschool Obergurgl	No abstract.
Waldauf 2017 MiPschool Obergurgl	Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates.	Oral
Yuan 2017 MiPschool Obergurgl	Participant MiPschool Obergurgl 2017.

Impressions from MiPschool Obergurgl 2017

Organizers

Georg Kandolf - Abstracts

Verena Laner MiPsociety General Secretary - General conference organization

Marija Beno, MitoEAGLE Administrative Representative - General conference organization

Erich Gnaiger, Chair COST Action MitoEAGLE and Chair MiPsociety - Main organizer

10 years ago

» MiPschool Schroecken AT 2007

Support

This project has received funding from the European Union's Horizon 2020 research and innovation programme supported by COST (European Cooperation in Science and Technology) under grant agreement No OC-2015-2-19984.

Listed under MitoGlobal Events.