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News and Events | Working Groups | Short-Term Scientific Missions | Management Committee | Members |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Kucera Otto
MitoPedia topics: EAGLE
COST WG3: WG3
Name | Kucera Otto, Assoc. Prof., M.D., PhD. |
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Institution |
Faculty of Medicine in Hradec Králové, Charles University in Prague, CZ |
Address | Šimkova 870, 500 38 |
City | Hradec Kralove |
State/Province | |
Country | Czech Republic |
[email protected] | |
Weblink | |
O2k-Network Lab | CZ Hradec Kralove Cervinkova Z |
Labels:
Publications
Published | Reference | |
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Endlicher 2021 Physiol Res | 2021 | Endlicher R, Drahota Z, Kučera O, Červinková Z (2021) Age-dependent changes in the function of mitochondrial membrane permeability transition pore in rat liver mitochondria. Physiol Res 70:905-11. |
Stankova 2021 Int J Mol Sci | 2021 | Staňková P, Kučera O, Peterová E, Elkalaf M, Rychtrmoc D, Melek J, Podhola M, Zubáňová V, Červinková Z (2021) Western diet decreases the liver mitochondrial oxidative flux of succinate: insight from a murine NAFLD model. https://doi.org/10.3390/ijms22136908 |
Stankova 2020 Int J Mol Sci | 2020 | Staňková P, Kučera O, Peterová E, Lotková H, Maseko TE, Nožičková K, Červinková Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101. |
BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 |
Kucera 2016 Drug Chem Toxicol | 2016 | Kučera O, Endlicher R, Rychtrmoc D, Lotková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56. |
Sobotka 2016 J Bioenerg Biomembr | 2016 | Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73. |
Cahova 2016 Am J Physiol Gastrointest Liver Physiol | 2016 | Cahova M, Palenickova E, Dankova H, Sticova E, Burian M, Drahota Z, Cervinkova Z, Kucera O, Gladkova C, Stopka P, Krizova J, Papackova Z, Oliyarnyk O, Kazdova L (2016) Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. Am J Physiol Gastrointest Liver Physiol 309:G100-11. |
Mezera 2016 Oxid Med Cell Longev | 2016 | Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp. |
Kucera 2015 Oxid Med Cell Longev | 2015 | Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180. |
Sobotka 2015 Physiol Res | 2015 | Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15. |
Garnol 2014 Physiol Res | 2014 | Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4. |
Kucera 2014 Oxid Med Cell Longev | 2014 | Kučera O, Endlicher R, Roušar T, Lotková H, Garnol T, Drahota Z, Cervinková Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes in vitro. Oxid Med Cell Longev 2014:752506. |
Kucera 2012 J Gastroenterol Hepatol | 2012 | Kucera O, Rousar T, Stankova P, Hanackova L, Lotkova H, Podhola M, Cervinkova Z (2012) Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. J Gastroenterol Hepatol 27:323-30. |
Kucera 2011 Int J Exp Pathol | 2011 | Kučera O, Lotková H, Staňková P, Podhola M, Roušar T, Mezera V, Cervinková Z (2011) Is rat liver affected by non-alcoholic steatosis more susceptible to the acute toxic effect of thioacetamide?. Int J Exp Pathol 92:281-9. |
Lotkova 2011 Gen Physiol Biophys | 2011 | Lotková H, Staňková P, Roušar T, Kučera O, Kohoutek L, Mičuda S, Brčáková E, Kolouchová G, Cervinková Z (2011) Deteriorating effect of fluvastatin on the cholestatic liver injury induced by bile duct ligation in rats. Gen Physiol Biophys 30:66-74. |
Kucera 2011 Physiol Res | 2011 | Kučera O, Garnol T, Lotková H, Staňková P, Mazurová Y, Hroch M, Bolehovská R, Roušar T, Červinková Z (2011) The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats. Physiol Res 60:317-28. |
Stankova 2010 Toxicol In Vitro | 2010 | Staňková P, Kučera O, Lotková H, Roušar T, Endlicher R, Cervinková Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103. |
Cervinkova 2009 Arch Toxicol | 2009 | Cervinková Z, Kriváková P, Lábajová A, Rousar T, Lotková H, Kucera O, Endlicher R, Cervinka M, Drahota Z (2009) Mechanisms participating in oxidative damage of isolated rat hepatocytes. Arch Toxicol 83:363-72. |
Lotkova 2009 Acta Vet Brno | 2009 | Lotková H, Kučera O, Roušar T, Endlicher R, Křiváková P, Garnol T, Červinková Z (2009) Effect of S-adenosylmethionine on Acetaminophen-induced toxic injury of rat hepatocytes in vitro. Acta Vet Brno 78:603-13. |
Cervinkova 2007 Altern Lab Anim | 2007 | Cervinkova Z, Lotkova H, Krivaikova P, Rousar T, Kucera O, Tichy L, Cervinka M, Drahota Z (2007) Evaluation of mitochondrial function in isolated rat hepatocytes and mitochondria during oxidative stress. Altern Lab Anim 35:353-61. |
Drahota 2005 Physiol Res | 2005 | Drahota Z, Krivakova P, Cervinkova Z, Kmonickova E, Lotkova H, Kucera O, Houstek J (2005) Tert-butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes. Physiol Res 54:67-72. |
Abstracts
Published | Reference | |
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Rodriguez-Hernandez 2018 Free Radic Biol Med | 2018 | Rodriguez-Hernández A, Staňková P, González R, De la Rosa AJ, Álamo-Martinez JM, Marin-Gómez LM, Sobotka O, Kučera O, Padillo FJ, Červinková Z, Muntané J (2018) The alteration of mitochondrial function is associated with the induction of endoplasmic reticulum stress autophagy and apoptosis by Sorafenib in liver cancer cells. Free Radic Biol Med. |
Stankova 2018 MiP2018 | 2018 | Impact of western diet on energy metabolism in mouse liver. |
Kucera 2017 MiP2017 | 2017 | Commonly used models of non-alcoholic fatty liver disease (NAFLD). |
Stankova 2017 MiP2017 | 2017 | Isolation of rat liver mitochondria for bioenergetic studies. |
Nozickova 2017 MiP2017 | 2017 | The early adaptation of rat liver mitochondria to high fat diet. |
Sobotka 2017 Abstract MITOEAGLE Barcelona | 2017 | The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation |
Sobotka 2017 MiP2017 | 2017 | Metabolic changes in rat liver mitochondria during the development of liver steatosis. |
Endlicher 2017 MiP2017 | 2017 | Age-related changes in isolated mitochondria from rat liver. |
Kovalcikova 2017 MiP2017 | 2017 | Mitochondrial protein TMEM70: key role in the biogenesis of ATP synthase verified in a mouse knockout model. |
Sobotka 2016 Abstract IOC116 | 2016 | Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11 |
Rousarova 2015 Abstract MiPschool London 2015 | 2015 | Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite. |
Cervinkova 2012 Abstract Bioblast | 2012 | Cervinkova Z, Stankova P, Cervinka M, Kucera O, Drahota Z (2012) Evaluation of mitochondrial functions – an important tool for experimental hepatology. Mitochondr Physiol Network 17.12. |